Experiment description of studies that identified MAP3K4 in sEVs

1 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

Protein-protein interactions for MAP3K4

Protein Interactor ExoCarta ID Identification method PubMed Species 1 MAP2K7 5609 Reconstituted Complex Homo sapiens 2 BAG3 9531 Affinity Capture-MS Homo sapiens 3 RIPK2   Affinity Capture-Western Homo sapiens 4 HNRNPD 3184 Affinity Capture-MS Homo sapiens 5 USF1   Affinity Capture-MS Homo sapiens 6 SIGLECL1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 7 MAP2K6 5608 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Co-localization Homo sapiens Biochemical Activity Homo sapiens Biochemical Activity Homo sapiens Biochemical Activity Homo sapiens Biochemical Activity Homo sapiens 8 POLR2F   Affinity Capture-MS Homo sapiens 9 SIRT6   Affinity Capture-MS Homo sapiens 10 AP4E1   Affinity Capture-MS Homo sapiens 11 ZFP36   Affinity Capture-Western Homo sapiens 12 ACTBL2 345651 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 13 GPR17 2840 Affinity Capture-MS Homo sapiens 14 GSK3B 2932 Biochemical Activity Homo sapiens 15 MAP2K4 6416 Reconstituted Complex Homo sapiens Biochemical Activity Homo sapiens 16 BAG6 7917 Affinity Capture-MS Homo sapiens 17 TRAF4 9618 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 18 YWHAZ 7534 Two-hybrid Homo sapiens 19 TPR 7175 Two-hybrid Homo sapiens 20 GADD45G   Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 21 GADD45A   Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 22 ACTA2 59 Affinity Capture-MS Homo sapiens 23 MAPK13 5603 Co-localization Homo sapiens 24 GOLT1B 51026 Affinity Capture-MS Homo sapiens 25 VWA9   Affinity Capture-MS Homo sapiens 26 SRPR 6734 Affinity Capture-MS Homo sapiens 27 GADD45B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 28 TOP1 7150 Synthetic Lethality Homo sapiens 29 BPNT1 10380 Affinity Capture-MS Homo sapiens 30 TOP3A   Synthetic Lethality Homo sapiens 31 KIF7 374654 Affinity Capture-MS Homo sapiens 32 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 33 SPATA1   Affinity Capture-MS Homo sapiens 34 MAP2K1 5604 Biochemical Activity Homo sapiens 35 CCT8L2   Affinity Capture-MS Homo sapiens 36 TOP2A 7153 Synthetic Lethality Homo sapiens 37 CDC42 998 Reconstituted Complex Homo sapiens Co-localization Homo sapiens 38 CNTRL   Two-hybrid Homo sapiens 39 SGTB   Affinity Capture-MS Homo sapiens 40 MAP2K3 5606 Reconstituted Complex Homo sapiens Co-localization Homo sapiens Biochemical Activity Homo sapiens Reconstituted Complex Homo sapiens 41 RAP1B 5908 Affinity Capture-MS Homo sapiens 42 MIB1 57534 Affinity Capture-Western Homo sapiens 43 CNTROB   Affinity Capture-MS Homo sapiens 44 NEDD1 121441 Affinity Capture-MS Homo sapiens 45 KIF23 9493 Affinity Capture-MS Homo sapiens 46 SORT1 6272 Affinity Capture-MS Homo sapiens 47 MAP3K4 4216 Biochemical Activity Homo sapiens Biochemical Activity Homo sapiens 48 SYNCRIP 10492 Affinity Capture-MS Homo sapiens 49 KIF21A 55605 Affinity Capture-MS Homo sapiens 50 PRC1 9055 Affinity Capture-MS Homo sapiens 51 S100B 6285 Affinity Capture-MS Homo sapiens 52 ACTB 60 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 53 SH3KBP1 30011 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 54 BTK 695 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 55 RAC1 5879 Reconstituted Complex Homo sapiens 56 Fign   Affinity Capture-MS Mus musculus 57 AXIN1   Affinity Capture-Western Homo sapiens 58 CIT 11113 Affinity Capture-MS Homo sapiens 59 MAPK8 5599 Affinity Capture-MS Homo sapiens Biochemical Activity Homo sapiens 60 CHUK 1147 Biochemical Activity Homo sapiens 61 ACTG1 71 Affinity Capture-MS Homo sapiens 62 ALK 238 Affinity Capture-MS Homo sapiens 63 Magoh   Affinity Capture-MS Mus musculus 64 DNAJC13 23317 Affinity Capture-MS Homo sapiens 65 AIFM1 9131 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens View the network

Pathways in which MAP3K4 is involved

No pathways found