Gene description for AIFM1
Gene name apoptosis-inducing factor, mitochondrion-associated, 1
Gene symbol AIFM1
Other names/aliases AIF
CMT2D
CMTX4
COWCK
COXPD6
NADMR
NAMSD
PDCD8
Species Homo sapiens
 Database cross references - AIFM1
ExoCarta ExoCarta_9131
Vesiclepedia VP_9131
Entrez Gene 9131
HGNC 8768
MIM 300169
UniProt O95831  
 AIFM1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for AIFM1
Molecular Function
    DNA binding GO:0003677 IDA
    NADH dehydrogenase activity GO:0003954 IEA
    protein binding GO:0005515 IPI
    NAD(P)H oxidase H2O2-forming activity GO:0016174 IBA
    NAD(P)H oxidase H2O2-forming activity GO:0016174 IDA
    NAD(P)H oxidase H2O2-forming activity GO:0016174 TAS
    oxidoreductase activity, acting on NAD(P)H GO:0016651 IDA
    protein dimerization activity GO:0046983 IEA
    FAD binding GO:0071949 IBA
    FAD binding GO:0071949 IDA
    poly-ADP-D-ribose binding GO:0072572 ISS
Biological Process
    response to ischemia GO:0002931 IEA
    apoptotic process GO:0006915 IBA
    apoptotic process GO:0006915 IMP
    response to toxic substance GO:0009636 IEA
    neuron differentiation GO:0030182 IDA
    chromosome condensation GO:0030261 TAS
    mitochondrial respiratory chain complex I assembly GO:0032981 IMP
    mitochondrial respiratory chain complex assembly GO:0033108 IBA
    mitochondrial respiratory chain complex assembly GO:0033108 IMP
    positive regulation of apoptotic process GO:0043065 TAS
    positive regulation of neuron apoptotic process GO:0043525 IEA
    protein import into mitochondrial intermembrane space GO:0045041 IMP
    neuron apoptotic process GO:0051402 IEA
    positive regulation of necroptotic process GO:0060545 ISS
    intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 ISS
    cellular response to hydrogen peroxide GO:0070301 IEA
    cellular response to estradiol stimulus GO:0071392 IEA
    cellular response to hypoxia GO:0071456 IEA
    cellular response to nitric oxide GO:0071732 IEA
    response to L-glutamate GO:1902065 IEA
    regulation of apoptotic DNA fragmentation GO:1902510 IEA
    cellular response to aldosterone GO:1904045 IEA
    positive regulation of cysteine-type endopeptidase activity GO:2001056 IDA
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISS
    cytoplasm GO:0005737 IBA
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial intermembrane space GO:0005758 IDA
    mitochondrial intermembrane space GO:0005758 IMP
    cytosol GO:0005829 ISS
    perinuclear region of cytoplasm GO:0048471 IEA
 Experiment description of studies that identified AIFM1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
10
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for AIFM1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SLC25A13 10165
Proximity Label-MS Homo sapiens
2 ARHGAP1 392
Co-fractionation Homo sapiens
3 Cdk1 12534
Affinity Capture-MS Mus musculus
4 DNAJC11 55735
Proximity Label-MS Homo sapiens
5 SHC1 6464
Affinity Capture-MS Homo sapiens
6 TRIAP1  
Proximity Label-MS Homo sapiens
7 RIN3  
Affinity Capture-MS Homo sapiens
8 TUBB8 347688
Affinity Capture-MS Homo sapiens
9 SOX2  
Affinity Capture-MS Homo sapiens
10 OXCT1 5019
Co-fractionation Homo sapiens
11 CKB 1152
Proximity Label-MS Homo sapiens
12 WDR76  
Affinity Capture-MS Homo sapiens
13 IARS2 55699
Proximity Label-MS Homo sapiens
14 ARMCX4  
Proximity Label-MS Homo sapiens
15 TIMM23 100287932
Proximity Label-MS Homo sapiens
16 KIAA1191  
Proximity Label-MS Homo sapiens
17 ETFA 2108
Proximity Label-MS Homo sapiens
18 PPEF1  
Affinity Capture-MS Homo sapiens
19 VPS13D 55187
Proximity Label-MS Homo sapiens
20 DYNLL1 8655
Co-fractionation Homo sapiens
21 PSMG1 8624
Co-fractionation Homo sapiens
22 BRF2  
Affinity Capture-MS Homo sapiens
23 SLC30A9 10463
Affinity Capture-MS Homo sapiens
24 BCS1L 617
Co-fractionation Homo sapiens
25 VWA8 23078
Proximity Label-MS Homo sapiens
26 P4HTM  
Affinity Capture-MS Homo sapiens
27 SLC25A3 5250
Affinity Capture-MS Homo sapiens
28 KIF14 9928
Affinity Capture-MS Homo sapiens
29 RBMX 27316
Co-fractionation Homo sapiens
30 KLF16  
Affinity Capture-MS Homo sapiens
31 MTMR11  
Affinity Capture-MS Homo sapiens
32 PGAM5 192111
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
33 VPS51 738
Affinity Capture-MS Homo sapiens
34 PSME1 5720
Co-fractionation Homo sapiens
35 SLC25A30 253512
Affinity Capture-MS Homo sapiens
36 MICU2 221154
Proximity Label-MS Homo sapiens
37 TUFM 7284
Affinity Capture-MS Homo sapiens
38 FAM162A 26355
Proximity Label-MS Homo sapiens
39 PTP4A3  
Affinity Capture-MS Homo sapiens
40 LHX1  
Affinity Capture-MS Homo sapiens
41 TDRP  
Proximity Label-MS Homo sapiens
42 NUDC 10726
Proximity Label-MS Homo sapiens
43 TRIM21 6737
Affinity Capture-MS Homo sapiens
44 NOS2  
Affinity Capture-MS Homo sapiens
45 HIST1H1C 3006
Co-fractionation Homo sapiens
46 DBT 1629
Proximity Label-MS Homo sapiens
47 CUL2 8453
Affinity Capture-MS Homo sapiens
48 AHCTF1 25909
Affinity Capture-MS Homo sapiens
49 MICU1 10367
Proximity Label-MS Homo sapiens
50 SLC25A5 292
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
51 SUOX  
Proximity Label-MS Homo sapiens
52 ANLN 54443
Affinity Capture-MS Homo sapiens
53 CISD1 55847
Proximity Label-MS Homo sapiens
54 EARS2  
Proximity Label-MS Homo sapiens
55 HADHA 3030
Proximity Label-MS Homo sapiens
56 HBS1L 10767
Affinity Capture-MS Homo sapiens
57 MTIF2 4528
Proximity Label-MS Homo sapiens
58 BAG1 573
Affinity Capture-MS Homo sapiens
59 CDCA3 83461
Proximity Label-MS Homo sapiens
60 CD274 29126
Affinity Capture-MS Homo sapiens
61 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 GPD2 2820
Proximity Label-MS Homo sapiens
63 FKBP8 23770
Proximity Label-MS Homo sapiens
64 TST 7263
Co-fractionation Homo sapiens
65 VARS2  
Proximity Label-MS Homo sapiens
66 SLC25A23  
Affinity Capture-MS Homo sapiens
67 TUBA4A 7277
Affinity Capture-MS Homo sapiens
68 ARMC6 93436
Affinity Capture-MS Homo sapiens
69 SOAT1 6646
Affinity Capture-MS Homo sapiens
70 RPA3 6119
Proximity Label-MS Homo sapiens
71 TIMM8B 26521
Proximity Label-MS Homo sapiens
72 DHRS7B 25979
Affinity Capture-MS Homo sapiens
73 HSPA1A 3303
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
74 GXYLT1 283464
Affinity Capture-MS Homo sapiens
75 SPATA5 166378
Affinity Capture-MS Homo sapiens
76 CRYBG3  
Proximity Label-MS Homo sapiens
77 ILK 3611
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 PARL  
Proximity Label-MS Homo sapiens
79 COX2 4513
Proximity Label-MS Homo sapiens
80 PEX3 8504
Affinity Capture-MS Homo sapiens
81 NFATC2  
Affinity Capture-MS Homo sapiens
82 CHCHD6 84303
Proximity Label-MS Homo sapiens
83 MRPL18 29074
Affinity Capture-MS Homo sapiens
84 HSPE1 3336
Cross-Linking-MS (XL-MS) Homo sapiens
85 GLS 2744
Proximity Label-MS Homo sapiens
86 CCDC58 131076
Proximity Label-MS Homo sapiens
87 Tubg1 103733
Affinity Capture-MS Mus musculus
88 CLPX 10845
Proximity Label-MS Homo sapiens
89 Tubb5 22154
Affinity Capture-MS Mus musculus
90 PLEC 5339
Co-fractionation Homo sapiens
91 SLC39A3  
Affinity Capture-MS Homo sapiens
92 RUVBL2 10856
Affinity Capture-MS Homo sapiens
93 ZEB1  
Affinity Capture-MS Homo sapiens
94 SUCLG2 8801
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
95 NUDT19 390916
Proximity Label-MS Homo sapiens
96 OAT 4942
Proximity Label-MS Homo sapiens
97 ATAD3A 55210
Proximity Label-MS Homo sapiens
98 HOXB1  
Affinity Capture-MS Homo sapiens
99 NCL 4691
Co-fractionation Homo sapiens
100 GM2A 2760
Affinity Capture-MS Homo sapiens
101 SNRNP70 6625
Cross-Linking-MS (XL-MS) Homo sapiens
102 ACOT1 641371
Proximity Label-MS Homo sapiens
103 SLC25A51  
Proximity Label-MS Homo sapiens
104 RDX 5962
Co-fractionation Homo sapiens
105 CAMTA1 23261
Affinity Capture-MS Homo sapiens
106 ADRM1 11047
Co-fractionation Homo sapiens
107 BLNK  
Affinity Capture-MS Homo sapiens
108 ANXA2 302
Co-fractionation Homo sapiens
109 NDUFS6  
Proximity Label-MS Homo sapiens
110 COX4I1 1327
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
111 AFG3L2 10939
Proximity Label-MS Homo sapiens
112 SPRTN  
Affinity Capture-MS Homo sapiens
113 MAGEA3  
Affinity Capture-MS Homo sapiens
114 GART 2618
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
115 PIDD1  
Affinity Capture-MS Homo sapiens
116 KCTD10 83892
Affinity Capture-MS Homo sapiens
117 ADRB2  
Affinity Capture-MS Homo sapiens
118 UCHL1 7345
Co-fractionation Homo sapiens
119 HSPA12B 116835
Affinity Capture-MS Homo sapiens
120 NDUFB5 4711
Proximity Label-MS Homo sapiens
121 FAM21A 387680
Cross-Linking-MS (XL-MS) Homo sapiens
122 FDXR 2232
Co-fractionation Homo sapiens
123 CAND1 55832
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
124 UNC93B1 81622
Affinity Capture-MS Homo sapiens
125 ASXL1  
Affinity Capture-MS Homo sapiens
126 SETDB1  
Two-hybrid Homo sapiens
127 GFRA1 2674
Co-fractionation Homo sapiens
128 HCCS 3052
Proximity Label-MS Homo sapiens
129 PPTC7 160760
Affinity Capture-MS Homo sapiens
130 Aurkb  
Affinity Capture-MS Mus musculus
131 B3GNT2 10678
Affinity Capture-MS Homo sapiens
132 OGDH 4967
Co-fractionation Homo sapiens
133 TUBB 203068
Affinity Capture-MS Homo sapiens
134 NR2F2  
Affinity Capture-MS Homo sapiens
135 ZFYVE1 53349
Affinity Capture-MS Homo sapiens
136 HADH 3033
Co-fractionation Homo sapiens
137 STIP1 10963
Co-fractionation Homo sapiens
138 C12orf73  
Proximity Label-MS Homo sapiens
139 LACTB 114294
Proximity Label-MS Homo sapiens
140 PHB 5245
Proximity Label-MS Homo sapiens
141 TOMM40 10452
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
142 NDUFV3 4731
Proximity Label-MS Homo sapiens
143 CUL1 8454
Affinity Capture-MS Homo sapiens
144 TIMM50 92609
Proximity Label-MS Homo sapiens
145 TACO1  
Proximity Label-MS Homo sapiens
146 FASTKD2  
Proximity Label-MS Homo sapiens
147 PDPR 55066
Proximity Label-MS Homo sapiens
148 TDRKH  
Proximity Label-MS Homo sapiens
149 FASTKD1  
Affinity Capture-MS Homo sapiens
150 AMBRA1  
Affinity Capture-MS Homo sapiens
151 DNAJB8 165721
Affinity Capture-MS Homo sapiens
152 USP10 9100
Affinity Capture-MS Homo sapiens
153 CORO7-PAM16 100529144
Proximity Label-MS Homo sapiens
154 AMFR 267
Affinity Capture-MS Homo sapiens
155 DRG1 4733
Proximity Label-MS Homo sapiens
156 NDUFA8 4702
Proximity Label-MS Homo sapiens
157 ATPAF1  
Proximity Label-MS Homo sapiens
158 BAG6 7917
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
159 SLC20A2 6575
Affinity Capture-MS Homo sapiens
160 TUBB2B 347733
Affinity Capture-MS Homo sapiens
161 TUBA1C 84790
Affinity Capture-MS Homo sapiens
162 GK  
Proximity Label-MS Homo sapiens
163 GET4 51608
Co-fractionation Homo sapiens
164 Ksr1  
Affinity Capture-MS Mus musculus
165 CYLD  
Affinity Capture-MS Homo sapiens
166 CARS 833
Co-fractionation Homo sapiens
167 ABCB7 22
Proximity Label-MS Homo sapiens
168 FBXL4 26235
Proximity Label-MS Homo sapiens
169 SGPL1 8879
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 SERPINA3 12
Affinity Capture-MS Homo sapiens
171 ICAM1 3383
Co-fractionation Homo sapiens
172 RC3H2  
Affinity Capture-MS Homo sapiens
173 PRKAR2A 5576
Proximity Label-MS Homo sapiens
174 KANK2 25959
Affinity Capture-MS Homo sapiens
175 RMND1 55005
Proximity Label-MS Homo sapiens
176 EGFR 1956
Affinity Capture-MS Homo sapiens
177 HSD17B10 3028
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
178 OMA1  
Proximity Label-MS Homo sapiens
179 MTFR1  
Proximity Label-MS Homo sapiens
180 MTFR2  
Proximity Label-MS Homo sapiens
181 RIPK4  
Affinity Capture-MS Homo sapiens
182 TOMM70A 9868
Proximity Label-MS Homo sapiens
183 FLNC 2318
Co-fractionation Homo sapiens
184 CNR2  
Affinity Capture-MS Homo sapiens
185 UBASH3A 53347
Affinity Capture-Western Homo sapiens
186 FAM91A1 157769
Affinity Capture-MS Homo sapiens
187 SCO1  
Proximity Label-MS Homo sapiens
188 ETV3  
Affinity Capture-MS Homo sapiens
189 DDB1 1642
Co-fractionation Homo sapiens
190 DDRGK1 65992
Affinity Capture-MS Homo sapiens
191 BMI1  
Affinity Capture-MS Homo sapiens
192 STX17 55014
Affinity Capture-MS Homo sapiens
193 HUWE1 10075
Affinity Capture-MS Homo sapiens
194 PHGDH 26227
Affinity Capture-MS Homo sapiens
195 PPIF 10105
Proximity Label-MS Homo sapiens
196 GSR 2936
Co-fractionation Homo sapiens
197 CLPP 8192
Proximity Label-MS Homo sapiens
198 C17orf80 55028
Proximity Label-MS Homo sapiens
199 GOT2 2806
Co-fractionation Homo sapiens
200 MYL6 4637
Proximity Label-MS Homo sapiens
201 HDGF 3068
Co-fractionation Homo sapiens
202 TP53 7157
Affinity Capture-MS Homo sapiens
203 RYK 6259
Affinity Capture-MS Homo sapiens
204 OXSR1 9943
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
205 MLH1 4292
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
206 OTUB1 55611
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
207 SHMT2 6472
Proximity Label-MS Homo sapiens
208 TOR1AIP1 26092
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
209 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
210 ME2 4200
Proximity Label-MS Homo sapiens
211 IDH2 3418
Co-fractionation Homo sapiens
212 BCL2L13 23786
Proximity Label-MS Homo sapiens
213 GFM1 85476
Proximity Label-MS Homo sapiens
214 PSMD1 5707
Affinity Capture-MS Homo sapiens
215 HNRNPA2B1 3181
Co-fractionation Homo sapiens
216 PRMT1 3276
Affinity Capture-MS Homo sapiens
217 TIMM13 26517
Proximity Label-MS Homo sapiens
218 DARS2 55157
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
219 ATAD1 84896
Proximity Label-MS Homo sapiens
220 GLRX5 51218
Co-fractionation Homo sapiens
221 SERPINB4 6318
Affinity Capture-MS Homo sapiens
222 RAB1A 5861
Co-fractionation Homo sapiens
223 MTX1 4580
Proximity Label-MS Homo sapiens
224 IRAK1  
Affinity Capture-MS Homo sapiens
225 PSMD10 5716
Co-fractionation Homo sapiens
226 PTPN1 5770
Proximity Label-MS Homo sapiens
227 RPS6KB2  
Affinity Capture-MS Homo sapiens
228 RTN4 57142
Affinity Capture-MS Homo sapiens
229 PELO 53918
Affinity Capture-MS Homo sapiens
230 Tubb4b 227613
Affinity Capture-MS Mus musculus
231 CUL4B 8450
Co-fractionation Homo sapiens
232 LRPPRC 10128
Proximity Label-MS Homo sapiens
233 RUVBL1 8607
Affinity Capture-MS Homo sapiens
234 HEATR3 55027
Affinity Capture-MS Homo sapiens
235 PTPN12 5782
Affinity Capture-MS Homo sapiens
236 TIMMDC1  
Proximity Label-MS Homo sapiens
237 TELO2 9894
Affinity Capture-MS Homo sapiens
238 SLC31A1 1317
Co-fractionation Homo sapiens
239 PSMC2 5701
Affinity Capture-MS Homo sapiens
240 SFXN4  
Affinity Capture-MS Homo sapiens
241 FAM136A 84908
Proximity Label-MS Homo sapiens
242 C20orf24  
Affinity Capture-MS Homo sapiens
243 UQCC3  
Proximity Label-MS Homo sapiens
244 MAVS 57506
Proximity Label-MS Homo sapiens
245 TFCP2 7024
Affinity Capture-MS Homo sapiens
246 ATP13A3 79572
Affinity Capture-MS Homo sapiens
247 NDUFS5 4725
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
248 CMC4  
Proximity Label-MS Homo sapiens
249 MDH2 4191
Proximity Label-MS Homo sapiens
250 ATAD3B 83858
Proximity Label-MS Homo sapiens
251 NSUN2 54888
Co-fractionation Homo sapiens
252 DLD 1738
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
253 SUCLG1 8802
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
254 CDC23 8697
Proximity Label-MS Homo sapiens
255 C17orf75 64149
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
256 EXOG 9941
Proximity Label-MS Homo sapiens
257 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
258 CHCHD3 54927
Proximity Label-MS Homo sapiens
259 MEX3C 51320
Affinity Capture-MS Homo sapiens
260 TUBA1A 7846
Affinity Capture-MS Homo sapiens
261 PANK4 55229
Affinity Capture-MS Homo sapiens
262 DIABLO 56616
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
263 ACACA 31
Positive Genetic Homo sapiens
264 TTC19  
Proximity Label-MS Homo sapiens
265 NTRK1 4914
Affinity Capture-MS Homo sapiens
266 IGHG4 3503
Affinity Capture-MS Homo sapiens
267 TPI1 7167
Co-fractionation Homo sapiens
268 FLNB 2317
Co-fractionation Homo sapiens
269 ACTB 60
Co-fractionation Homo sapiens
270 COA7  
Proximity Label-MS Homo sapiens
271 EIF3H 8667
Affinity Capture-MS Homo sapiens
272 LYPLA1 10434
Affinity Capture-MS Homo sapiens
273 YAP1 10413
Affinity Capture-MS Homo sapiens
274 MTHFD1L 25902
Proximity Label-MS Homo sapiens
275 MFF 56947
Proximity Label-MS Homo sapiens
276 TNFAIP2 7127
Affinity Capture-MS Homo sapiens
277 ENDOG  
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
278 HEATR6  
Affinity Capture-MS Homo sapiens
279 TONSL  
Affinity Capture-MS Homo sapiens
280 ACAT1 38
Co-fractionation Homo sapiens
281 SMCR8 140775
Proximity Label-MS Homo sapiens
282 AK2 204
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
283 SLC25A12 8604
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
284 TRMT10C 54931
Proximity Label-MS Homo sapiens
285 ECT2 1894
Affinity Capture-MS Homo sapiens
286 ARFGEF1 10565
Co-fractionation Homo sapiens
287 S100A7 6278
Affinity Capture-MS Homo sapiens
288 FBXO6 26270
Affinity Capture-MS Homo sapiens
289 DHX30 22907
Proximity Label-MS Homo sapiens
290 OCIAD1 54940
Proximity Label-MS Homo sapiens
291 CECR5 27440
Affinity Capture-MS Homo sapiens
292 PSMB10 5699
Affinity Capture-MS Homo sapiens
293 MED10  
Proximity Label-MS Homo sapiens
294 AMZ1  
Affinity Capture-MS Homo sapiens
295 RNF2  
Affinity Capture-MS Homo sapiens
296 CLPB 81570
Proximity Label-MS Homo sapiens
297 HAX1  
Proximity Label-MS Homo sapiens
298 HSPA9 3313
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
299 ARAF 369
Affinity Capture-MS Homo sapiens
300 MARC2 54996
Proximity Label-MS Homo sapiens
301 AKAP1 8165
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
302 C1orf112  
Affinity Capture-MS Homo sapiens
303 HIF1A 3091
Affinity Capture-MS Homo sapiens
304 ATP6V1H 51606
Affinity Capture-MS Homo sapiens
305 IMMT 10989
Proximity Label-MS Homo sapiens
306 HECTD1 25831
Affinity Capture-MS Homo sapiens
307 SUGT1 10910
Proximity Label-MS Homo sapiens
308 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
309 PHB2 11331
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
310 ALDH3A2 224
Proximity Label-MS Homo sapiens
311 CCT8 10694
Co-fractionation Homo sapiens
312 FBXL6  
Affinity Capture-MS Homo sapiens
313 NDUFAF2  
Proximity Label-MS Homo sapiens
314 SERAC1 84947
Proximity Label-MS Homo sapiens
315 PDHA1 5160
Affinity Capture-MS Homo sapiens
316 TUBB3 10381
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
317 MLF2 8079
Affinity Capture-MS Homo sapiens
318 GRPEL1 80273
Co-fractionation Homo sapiens
319 S100A9 6280
Affinity Capture-MS Homo sapiens
320 UFL1 23376
Affinity Capture-MS Homo sapiens
321 ETV7  
Affinity Capture-MS Homo sapiens
322 SMIM12  
Proximity Label-MS Homo sapiens
323 FLNA 2316
Co-fractionation Homo sapiens
324 DPF3  
Affinity Capture-MS Homo sapiens
325 CIT 11113
Affinity Capture-MS Homo sapiens
326 HNRNPF 3185
Co-fractionation Homo sapiens
327 SPG20 23111
Affinity Capture-MS Homo sapiens
328 Cdc6 23834
Affinity Capture-MS Mus musculus
329 SERBP1 26135
Affinity Capture-MS Homo sapiens
330 STC2 8614
Two-hybrid Homo sapiens
331 RC3H1 149041
Affinity Capture-MS Homo sapiens
332 ATXN3 4287
Affinity Capture-MS Homo sapiens
333 TIMM44 10469
Proximity Label-MS Homo sapiens
334 EP300 2033
Affinity Capture-MS Homo sapiens
335 SCO2  
Proximity Label-MS Homo sapiens
336 HLA-C 3107
Affinity Capture-MS Homo sapiens
337 UBE2H 7328
Affinity Capture-MS Homo sapiens
338 XIAP  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
339 CPOX 1371
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
340 TUBB4B 10383
Affinity Capture-MS Homo sapiens
341 KARS 3735
Co-fractionation Homo sapiens
342 HSD17B12 51144
Affinity Capture-MS Homo sapiens
343 DCAF11  
Affinity Capture-MS Homo sapiens
344 TOMM22 56993
Proximity Label-MS Homo sapiens
345 USP36  
Affinity Capture-MS Homo sapiens
346 KIAA1429 25962
Affinity Capture-MS Homo sapiens
347 CHCHD4  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
348 PSMD2 5708
Affinity Capture-MS Homo sapiens
349 TSC22D4 81628
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
350 KLF8  
Affinity Capture-MS Homo sapiens
351 CKMT1A 548596
Proximity Label-MS Homo sapiens
352 COPS5 10987
Affinity Capture-MS Homo sapiens
353 FBXW7  
Affinity Capture-MS Homo sapiens
354 IMPDH2 3615
Co-fractionation Homo sapiens
355 MRPS24 64951
Proximity Label-MS Homo sapiens
356 PSMC6 5706
Affinity Capture-MS Homo sapiens
357 ABCE1 6059
Affinity Capture-MS Homo sapiens
358 FANCI 55215
Affinity Capture-MS Homo sapiens
359 EXD2  
Proximity Label-MS Homo sapiens
360 NFXL1 152518
Affinity Capture-MS Homo sapiens
361 SLC25A25  
Proximity Label-MS Homo sapiens
362 PMS2  
Affinity Capture-MS Homo sapiens
363 FAF2 23197
Proximity Label-MS Homo sapiens
364 CTU1 90353
Affinity Capture-MS Homo sapiens
365 TMEM63B 55362
Affinity Capture-MS Homo sapiens
366 APOO 79135
Proximity Label-MS Homo sapiens
367 POLD1 5424
Affinity Capture-MS Homo sapiens
368 PRDX5 25824
Co-fractionation Homo sapiens
369 COX15 1355
Proximity Label-MS Homo sapiens
370 PCK2 5106
Proximity Label-MS Homo sapiens
371 NAA50 80218
Proximity Label-MS Homo sapiens
372 PSMD4 5710
Affinity Capture-MS Homo sapiens
373 ERBB3 2065
Affinity Capture-MS Homo sapiens
374 TXN 7295
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
375 ACOT2 10965
Proximity Label-MS Homo sapiens
376 GBF1 8729
Affinity Capture-MS Homo sapiens
377 STAU1 6780
Affinity Capture-MS Homo sapiens
378 SERPINH1 871
Co-fractionation Homo sapiens
379 OPA1 4976
Proximity Label-MS Homo sapiens
380 TARS2 80222
Proximity Label-MS Homo sapiens
381 FH 2271
Co-fractionation Homo sapiens
382 ERAL1  
Proximity Label-MS Homo sapiens
383 CDK9 1025
Affinity Capture-MS Homo sapiens
384 RHOT2 89941
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
385 ATP5B 506
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
386 DNAJB11 51726
Co-fractionation Homo sapiens
387 SNAP29 9342
Proximity Label-MS Homo sapiens
388 BAG3 9531
Affinity Capture-MS Homo sapiens
389 STK10 6793
Co-fractionation Homo sapiens
390 SLC25A24 29957
Proximity Label-MS Homo sapiens
391 CYB5B 80777
Proximity Label-MS Homo sapiens
392 SERPINB3 6317
Affinity Capture-MS Homo sapiens
393 GFER  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
394 C19orf52  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
395 NDUFB10 4716
Proximity Label-MS Homo sapiens
396 OTUD1 220213
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
397 ACAD10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
398 LETM1 3954
Proximity Label-MS Homo sapiens
399 HCFC1 3054
Co-fractionation Homo sapiens
400 NFS1 9054
Proximity Label-MS Homo sapiens
401 SLC35E1 79939
Affinity Capture-MS Homo sapiens
402 ELAC2 60528
Proximity Label-MS Homo sapiens
403 SUZ12  
Affinity Capture-MS Homo sapiens
404 NXF1 10482
Affinity Capture-RNA Homo sapiens
405 AURKB 9212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
406 ASB12  
Affinity Capture-MS Homo sapiens
407 HIGD2A  
Proximity Label-MS Homo sapiens
408 PRKACA 5566
Affinity Capture-MS Homo sapiens
409 YME1L1 10730
Proximity Label-MS Homo sapiens
410 APOOL 139322
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
411 COX6B1 1340
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
412 MAP3K4 4216
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
413 HK1 3098
Proximity Label-MS Homo sapiens
414 VDAC1 7416
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
415 BDH1 622
Affinity Capture-MS Homo sapiens
416 FSCN1 6624
Co-fractionation Homo sapiens
417 CCDC8  
Affinity Capture-MS Homo sapiens
418 H2AFX 3014
Affinity Capture-MS Homo sapiens
419 GLUD1 2746
Proximity Label-MS Homo sapiens
420 SLC25A11 8402
Affinity Capture-MS Homo sapiens
421 SIRT6  
Affinity Capture-MS Homo sapiens
422 BKRF1  
Affinity Capture-MS
423 UBXN4 23190
Proximity Label-MS Homo sapiens
424 DNAJA2 10294
Proximity Label-MS Homo sapiens
425 ZNF746  
Affinity Capture-MS Homo sapiens
426 MRPS31  
Proximity Label-MS Homo sapiens
427 COX16  
Proximity Label-MS Homo sapiens
428 CUL5 8065
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
429 UBA52 7311
Co-fractionation Homo sapiens
430 GPD1L 23171
Affinity Capture-MS Homo sapiens
431 OPA3 80207
Proximity Label-MS Homo sapiens
432 TUBB4A 10382
Affinity Capture-MS Homo sapiens
433 SFXN1 94081
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
434 IDE 3416
Co-fractionation Homo sapiens
435 USP30  
Proximity Label-MS Homo sapiens
436 THAP4 51078
Affinity Capture-MS Homo sapiens
437 TRIM31  
Affinity Capture-MS Homo sapiens
438 PINK1  
Affinity Capture-MS Homo sapiens
439 NDUFAF4 29078
Proximity Label-MS Homo sapiens
440 C9orf72  
Affinity Capture-MS Homo sapiens
441 KBTBD4  
Affinity Capture-MS Homo sapiens
442 HSPA12A 259217
Affinity Capture-MS Homo sapiens
443 PTPN18 26469
Affinity Capture-MS Homo sapiens
444 TUBA3E 112714
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which AIFM1 is involved
No pathways found





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