Gene description for TELO2
Gene name telomere maintenance 2
Gene symbol TELO2
Other names/aliases CLK2
TEL2
Species Homo sapiens
 Database cross references - TELO2
ExoCarta ExoCarta_9894
Vesiclepedia VP_9894
Entrez Gene 9894
HGNC 29099
MIM 611140
UniProt Q9Y4R8  
 TELO2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
Thymus 23844026    
 Gene ontology annotations for TELO2
Molecular Function
    protein binding GO:0005515 IPI
    protein complex binding GO:0032403 IDA
    protein complex scaffold GO:0032947 IEA
Biological Process
    regulation of TOR signaling GO:0032006 IMP
Subcellular Localization
    TORC2 complex GO:0031932 IDA
    TORC1 complex GO:0031931 IDA
    cytoplasm GO:0005737 IDA
    nucleus GO:0005634 IDA
    chromosome, telomeric region GO:0000781 IEA
    intracellular GO:0005622 IDA
    membrane GO:0016020 IEA
 Experiment description of studies that identified TELO2 in exosomes
1
Experiment ID 488
MISEV standards
EM
EV Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
CANX
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 217
MISEV standards
EM
EV Biophysical techniques
TSG101|CD81|CD9|CD63
EV Enriched markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TELO2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MAGED1 9500
Affinity Capture-MS Homo sapiens
2 PSMD6 9861
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TELO2 is involved
No pathways found





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