Gene description for BRD1
Gene name bromodomain containing 1
Gene symbol BRD1
Other names/aliases BRL
BRPF1
BRPF2
Species Homo sapiens
 Database cross references - BRD1
ExoCarta ExoCarta_23774
Vesiclepedia VP_23774
Entrez Gene 23774
HGNC 1102
MIM 604589
 BRD1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for BRD1
Molecular Function
    histone binding GO:0042393 IDA
    zinc ion binding GO:0008270 IEA
Biological Process
    histone H3 acetylation GO:0043966 IDA
Subcellular Localization
    nucleus GO:0005634 TAS
    MOZ/MORF histone acetyltransferase complex GO:0070776 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified BRD1 in exosomes
1
Experiment ID 235
MISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Enriched markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for BRD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 VIM 7431
Two-hybrid Homo sapiens
2 KIAA1377  
Two-hybrid Homo sapiens
3 TAL1  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which BRD1 is involved
No pathways found





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