Gene description for WRNIP1
Gene name Werner helicase interacting protein 1
Gene symbol WRNIP1
Other names/aliases WHIP
bA420G6.2
Species Homo sapiens
 Database cross references - WRNIP1
ExoCarta ExoCarta_56897
Entrez Gene 56897
HGNC 20876
MIM 608196
UniProt Q96S55  
 WRNIP1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for WRNIP1
Molecular Function
    ATPase activity GO:0016887 IMP
    DNA binding GO:0003677 IEA
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
    ATP binding GO:0005524 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    DNA replication GO:0006260 IEA
    DNA synthesis involved in DNA repair GO:0000731 IDA
    regulation of DNA-dependent DNA replication initiation GO:0030174 IDA
Subcellular Localization
    nucleus GO:0005634 ISS
    membrane GO:0016020 IDA
    perinuclear region of cytoplasm GO:0048471 IDA
 Experiment description of studies that identified WRNIP1 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for WRNIP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 WRN  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which WRNIP1 is involved
No pathways found





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