Gene description for C16orf72
Gene name chromosome 16 open reading frame 72
Gene symbol C16orf72
Other names/aliases PRO0149
Species Homo sapiens
 Database cross references - C16orf72
ExoCarta ExoCarta_29035
Vesiclepedia VP_29035
Entrez Gene 29035
HGNC 30103
UniProt Q14CZ0  
 C16orf72 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for C16orf72
Molecular Function
    protein binding GO:0005515 IPI
    ubiquitin protein ligase binding GO:0031625 IPI
Biological Process
    regulation of cellular response to stress GO:0080135 IDA
    negative regulation of signal transduction by p53 class mediator GO:1901797 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified C16orf72 in exosomes
1
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for C16orf72
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
2 RALY 22913
Affinity Capture-MS Homo sapiens
3 HACD3 51495
Affinity Capture-MS Homo sapiens
4 MCM7 4176
Affinity Capture-MS Homo sapiens
5 SSR4 6748
Affinity Capture-MS Homo sapiens
6 SLIT2 9353
Affinity Capture-MS Homo sapiens
7 ABLIM1 3983
Affinity Capture-MS Homo sapiens
8 BIRC6 57448
Affinity Capture-MS Homo sapiens
9 GSTP1 2950
Affinity Capture-MS Homo sapiens
10 KPNA3 3839
Affinity Capture-MS Homo sapiens
11 UBL4A 8266
Affinity Capture-MS Homo sapiens
12 DBNL 28988
Affinity Capture-MS Homo sapiens
13 ADCK3  
Affinity Capture-MS Homo sapiens
14 KPNA1 3836
Affinity Capture-MS Homo sapiens
15 TBC1D4  
Affinity Capture-MS Homo sapiens
16 TTC4  
Affinity Capture-MS Homo sapiens
17 IPO7 10527
Affinity Capture-MS Homo sapiens
18 TNPO1 3842
Affinity Capture-MS Homo sapiens
19 LDHA 3939
Affinity Capture-MS Homo sapiens
20 RRS1 23212
Affinity Capture-MS Homo sapiens
21 NCDN 23154
Affinity Capture-MS Homo sapiens
22 BZW2 28969
Affinity Capture-MS Homo sapiens
23 HLA-B 3106
Affinity Capture-MS Homo sapiens
24 CDC34 997
Affinity Capture-MS Homo sapiens
25 KPNB1 3837
Affinity Capture-MS Homo sapiens
26 FAM9B  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
27 PBK  
Affinity Capture-MS Homo sapiens
28 VPS35 55737
Affinity Capture-MS Homo sapiens
29 EMD 2010
Affinity Capture-MS Homo sapiens
30 COPB2 9276
Affinity Capture-MS Homo sapiens
31 USP9X 8239
Affinity Capture-MS Homo sapiens
32 C1QBP 708
Affinity Capture-MS Homo sapiens
33 ARCN1 372
Affinity Capture-MS Homo sapiens
34 RIOK3 8780
Affinity Capture-MS Homo sapiens
35 CAND1 55832
Affinity Capture-MS Homo sapiens
36 LRRC59 55379
Affinity Capture-MS Homo sapiens
37 SRP72 6731
Affinity Capture-MS Homo sapiens
38 GCN1L1 10985
Affinity Capture-MS Homo sapiens
39 PELO 53918
Affinity Capture-MS Homo sapiens
40 CEP97 79598
Affinity Capture-MS Homo sapiens
41 PI4KA 5297
Affinity Capture-MS Homo sapiens
42 WDTC1 23038
Affinity Capture-MS Homo sapiens
43 HSPA4 3308
Affinity Capture-MS Homo sapiens
44 RNH1 6050
Affinity Capture-MS Homo sapiens
45 HPRT1 3251
Affinity Capture-MS Homo sapiens
46 DDB1 1642
Affinity Capture-MS Homo sapiens
47 MARK2 2011
Affinity Capture-MS Homo sapiens
48 NDUFS3 4722
Affinity Capture-MS Homo sapiens
49 DPM1 8813
Affinity Capture-MS Homo sapiens
50 RFC3 5983
Affinity Capture-MS Homo sapiens
51 HEATR1 55127
Affinity Capture-MS Homo sapiens
52 HIST3H2A 92815
Affinity Capture-MS Homo sapiens
53 VPS51 738
Affinity Capture-MS Homo sapiens
54 VARS 7407
Affinity Capture-MS Homo sapiens
55 MPP5 64398
Affinity Capture-MS Homo sapiens
56 NME7 29922
Affinity Capture-MS Homo sapiens
57 COPS6 10980
Affinity Capture-MS Homo sapiens
58 VIMP 55829
Affinity Capture-MS Homo sapiens
59 NUP153 9972
Affinity Capture-MS Homo sapiens
60 KIF5B 3799
Affinity Capture-MS Homo sapiens
61 RRP12 23223
Affinity Capture-MS Homo sapiens
62 ANP32B 10541
Affinity Capture-MS Homo sapiens
63 COPS5 10987
Affinity Capture-MS Homo sapiens
64 NFE2L2 4780
Affinity Capture-MS Homo sapiens
65 IMPDH2 3615
Affinity Capture-MS Homo sapiens
66 SCRIB 23513
Affinity Capture-MS Homo sapiens
67 STT3A 3703
Affinity Capture-MS Homo sapiens
68 MCTS1 28985
Affinity Capture-MS Homo sapiens
69 HSPH1 10808
Affinity Capture-MS Homo sapiens
70 PPP6R1 22870
Affinity Capture-MS Homo sapiens
71 INTS12  
Two-hybrid Homo sapiens
72 ATP2A2 488
Affinity Capture-MS Homo sapiens
73 DDOST 1650
Affinity Capture-MS Homo sapiens
74 SFXN4  
Affinity Capture-MS Homo sapiens
75 ARF4 378
Affinity Capture-MS Homo sapiens
76 NME1-NME2 654364
Affinity Capture-MS Homo sapiens
77 CLPB 81570
Affinity Capture-MS Homo sapiens
78 FANCD2  
Affinity Capture-MS Homo sapiens
79 GRWD1 83743
Affinity Capture-MS Homo sapiens
80 SRP68 6730
Affinity Capture-MS Homo sapiens
81 UFC1 51506
Affinity Capture-MS Homo sapiens
82 ANAPC7 51434
Affinity Capture-MS Homo sapiens
83 AASDHPPT 60496
Affinity Capture-MS Homo sapiens
84 PRDX4 10549
Affinity Capture-MS Homo sapiens
85 INADL 10207
Affinity Capture-MS Homo sapiens
86 NME2 4831
Affinity Capture-MS Homo sapiens
87 PFN2 5217
Affinity Capture-MS Homo sapiens
88 CTPS1 1503
Affinity Capture-MS Homo sapiens
89 RNF126  
Affinity Capture-MS Homo sapiens
90 TIMM50 92609
Affinity Capture-MS Homo sapiens
91 GPX8 493869
Affinity Capture-MS Homo sapiens
92 GPS1 2873
Affinity Capture-MS Homo sapiens
93 SDCBP 6386
Affinity Capture-MS Homo sapiens
94 USP7 7874
Affinity Capture-MS Homo sapiens
95 FAF2 23197
Affinity Capture-MS Homo sapiens
96 CPOX 1371
Affinity Capture-MS Homo sapiens
97 GNPAT 8443
Affinity Capture-MS Homo sapiens
98 HSD17B10 3028
Affinity Capture-MS Homo sapiens
99 CPNE3 8895
Affinity Capture-MS Homo sapiens
100 AHCYL1 10768
Affinity Capture-MS Homo sapiens
101 PRPS2 5634
Affinity Capture-MS Homo sapiens
102 NUP133 55746
Affinity Capture-MS Homo sapiens
103 ADSL 158
Affinity Capture-MS Homo sapiens
104 ECD  
Affinity Capture-MS Homo sapiens
105 PSME3 10197
Affinity Capture-MS Homo sapiens
106 NUP155 9631
Affinity Capture-MS Homo sapiens
107 UNK  
Affinity Capture-RNA Homo sapiens
108 GARS 2617
Affinity Capture-MS Homo sapiens
109 URB1 9875
Affinity Capture-MS Homo sapiens
110 PRDX2 7001
Affinity Capture-MS Homo sapiens
111 SDHA 6389
Affinity Capture-MS Homo sapiens
112 TUBA1B 10376
Affinity Capture-MS Homo sapiens
113 SLC1A5 6510
Affinity Capture-MS Homo sapiens
114 GMDS 2762
Affinity Capture-MS Homo sapiens
115 NUP188 23511
Affinity Capture-MS Homo sapiens
116 TRIM26 7726
Affinity Capture-MS Homo sapiens
117 CDC23 8697
Affinity Capture-MS Homo sapiens
118 SRP14 6727
Affinity Capture-MS Homo sapiens
119 HMGCS1 3157
Affinity Capture-MS Homo sapiens
120 WDR73  
Affinity Capture-MS Homo sapiens
121 MRPS34 65993
Affinity Capture-MS Homo sapiens
122 MAP1B 4131
Affinity Capture-MS Homo sapiens
123 COPE 11316
Affinity Capture-MS Homo sapiens
124 ALDH18A1 5832
Affinity Capture-MS Homo sapiens
125 COPG1 22820
Affinity Capture-MS Homo sapiens
126 MARS 4141
Affinity Capture-MS Homo sapiens
127 PRICKLE3  
Affinity Capture-MS Homo sapiens
128 BAG6 7917
Affinity Capture-MS Homo sapiens
129 ATP5O 539
Affinity Capture-MS Homo sapiens
130 COPB1 1315
Affinity Capture-MS Homo sapiens
131 KPNA4 3840
Affinity Capture-MS Homo sapiens
132 XPOT 11260
Affinity Capture-MS Homo sapiens
133 CPVL 54504
Affinity Capture-MS Homo sapiens
134 UCHL5 51377
Affinity Capture-MS Homo sapiens
135 UBR5 51366
Affinity Capture-MS Homo sapiens
136 CARM1 10498
Affinity Capture-MS Homo sapiens
137 ANKHD1 54882
Affinity Capture-MS Homo sapiens
138 SREBF2 6721
Negative Genetic Homo sapiens
139 NUDC 10726
Affinity Capture-MS Homo sapiens
140 LAS1L 81887
Affinity Capture-MS Homo sapiens
141 DCP1A 55802
Affinity Capture-MS Homo sapiens
142 CHEK1  
Affinity Capture-MS Homo sapiens
143 ANAPC5 51433
Affinity Capture-MS Homo sapiens
144 KLHL11  
Affinity Capture-MS Homo sapiens
145 PYCRL 65263
Affinity Capture-MS Homo sapiens
146 DCTPP1 79077
Affinity Capture-MS Homo sapiens
147 CYC1 1537
Affinity Capture-MS Homo sapiens
148 MTMR1 8776
Affinity Capture-MS Homo sapiens
149 TUBA1C 84790
Affinity Capture-MS Homo sapiens
150 COPS3 8533
Affinity Capture-MS Homo sapiens
151 PRKDC 5591
Affinity Capture-MS Homo sapiens
152 UBE2D3 7323
Affinity Capture-MS Homo sapiens
153 ANXA1 301
Affinity Capture-MS Homo sapiens
154 PKM 5315
Affinity Capture-MS Homo sapiens
155 ATP5H 10476
Affinity Capture-MS Homo sapiens
156 MTHFD1 4522
Affinity Capture-MS Homo sapiens
157 VCPIP1 80124
Affinity Capture-MS Homo sapiens
158 GET4 51608
Affinity Capture-MS Homo sapiens
159 PPM1G 5496
Affinity Capture-MS Homo sapiens
160 PAICS 10606
Affinity Capture-MS Homo sapiens
161 VARS2  
Affinity Capture-MS Homo sapiens
162 CACYBP 27101
Affinity Capture-MS Homo sapiens
163 ITM2B 9445
Affinity Capture-MS Homo sapiens
164 CDIPT 10423
Affinity Capture-MS Homo sapiens
165 FAM127B  
Affinity Capture-MS Homo sapiens
166 CAD 790
Affinity Capture-MS Homo sapiens
167 PHB 5245
Affinity Capture-MS Homo sapiens
168 SEC63 11231
Affinity Capture-MS Homo sapiens
169 CNOT3 4849
Affinity Capture-MS Homo sapiens
170 HSPA5 3309
Affinity Capture-MS Homo sapiens
171 PLAA 9373
Affinity Capture-MS Homo sapiens
172 OLA1 29789
Affinity Capture-MS Homo sapiens
173 TUBB 203068
Affinity Capture-MS Homo sapiens
174 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
175 USP4 7375
Affinity Capture-MS Homo sapiens
176 AHSA1 10598
Affinity Capture-MS Homo sapiens
177 RPN2 6185
Affinity Capture-MS Homo sapiens
178 HBS1L 10767
Affinity Capture-MS Homo sapiens
179 SMARCAD1  
Affinity Capture-MS Homo sapiens
180 MSH2 4436
Affinity Capture-MS Homo sapiens
181 TIPRL 261726
Affinity Capture-MS Homo sapiens
182 XPO1 7514
Affinity Capture-MS Homo sapiens
183 USP15 9958
Affinity Capture-MS Homo sapiens
184 WRNIP1 56897
Affinity Capture-MS Homo sapiens
185 PPP2CB 5516
Affinity Capture-MS Homo sapiens
186 HIST2H2BF 440689
Affinity Capture-MS Homo sapiens
187 PPA1 5464
Affinity Capture-MS Homo sapiens
188 EEF2 1938
Affinity Capture-MS Homo sapiens
189 GTF3C1  
Affinity Capture-MS Homo sapiens
190 RFC2 5982
Affinity Capture-MS Homo sapiens
191 ATP5F1 515
Affinity Capture-MS Homo sapiens
192 TUBB4B 10383
Affinity Capture-MS Homo sapiens
193 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
194 FKBP8 23770
Affinity Capture-MS Homo sapiens
195 PPP2R2A 5520
Affinity Capture-MS Homo sapiens
196 RPP30 10556
Affinity Capture-MS Homo sapiens
197 ATP1B3 483
Affinity Capture-MS Homo sapiens
198 BAP1 8314
Negative Genetic Homo sapiens
199 EPRS 2058
Affinity Capture-MS Homo sapiens
200 PPP6R3 55291
Affinity Capture-MS Homo sapiens
201 ELP2 55250
Affinity Capture-MS Homo sapiens
202 SDHB 6390
Affinity Capture-MS Homo sapiens
203 DNAJA1 3301
Affinity Capture-MS Homo sapiens
204 ARL1 400
Affinity Capture-MS Homo sapiens
205 RNF138  
Affinity Capture-MS Homo sapiens
206 DCAF8 50717
Affinity Capture-MS Homo sapiens
207 TELO2 9894
Affinity Capture-MS Homo sapiens
208 SLC25A11 8402
Affinity Capture-MS Homo sapiens
209 FARSB 10056
Affinity Capture-MS Homo sapiens
210 POLE3  
Affinity Capture-MS Homo sapiens
211 MOGS 7841
Affinity Capture-MS Homo sapiens
212 GANAB 23193
Affinity Capture-MS Homo sapiens
213 CMSS1  
Affinity Capture-MS Homo sapiens
214 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
215 RPA3 6119
Affinity Capture-MS Homo sapiens
216 CDK4 1019
Affinity Capture-MS Homo sapiens
217 SET 6418
Affinity Capture-MS Homo sapiens
218 DIS3 22894
Affinity Capture-MS Homo sapiens
219 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
220 DHPS 1725
Affinity Capture-MS Homo sapiens
221 KIAA1524 57650
Affinity Capture-MS Homo sapiens
222 HSPA1A 3303
Affinity Capture-MS Homo sapiens
223 EXOSC5 56915
Affinity Capture-MS Homo sapiens
224 CDC45  
Affinity Capture-MS Homo sapiens
225 SLC25A18  
Affinity Capture-MS Homo sapiens
226 TCEB2 6923
Affinity Capture-MS Homo sapiens
227 PPP6C 5537
Affinity Capture-MS Homo sapiens
228 NOB1  
Affinity Capture-MS Homo sapiens
229 PLS3 5358
Affinity Capture-MS Homo sapiens
230 SGTA 6449
Affinity Capture-MS Homo sapiens
231 ARID1A 8289
Negative Genetic Homo sapiens
232 HSPA4L 22824
Affinity Capture-MS Homo sapiens
233 HAX1  
Affinity Capture-MS Homo sapiens
234 CSDE1 7812
Affinity Capture-MS Homo sapiens
235 AARS 16
Affinity Capture-MS Homo sapiens
236 MPDZ  
Affinity Capture-MS Homo sapiens
237 LANCL2 55915
Affinity Capture-MS Homo sapiens
238 RPTOR 57521
Affinity Capture-MS Homo sapiens
239 SLC25A13 10165
Affinity Capture-MS Homo sapiens
240 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
241 NCAPG 64151
Affinity Capture-MS Homo sapiens
242 TCF25 22980
Affinity Capture-MS Homo sapiens
243 IQGAP1 8826
Affinity Capture-MS Homo sapiens
244 CSE1L 1434
Affinity Capture-MS Homo sapiens
245 TUBB2A 7280
Affinity Capture-MS Homo sapiens
246 UCK2 7371
Affinity Capture-MS Homo sapiens
247 THOC1 9984
Affinity Capture-MS Homo sapiens
248 RHOBTB3 22836
Affinity Capture-MS Homo sapiens
249 PPP4C 5531
Affinity Capture-MS Homo sapiens
250 PPP2R5E 5529
Affinity Capture-MS Homo sapiens
251 RPS3 6188
Affinity Capture-MS Homo sapiens
252 GRB2 2885
Affinity Capture-MS Homo sapiens
253 ANKHD1-EIF4EBP3  
Affinity Capture-MS Homo sapiens
254 C11orf58  
Affinity Capture-MS Homo sapiens
255 THUMPD3 25917
Affinity Capture-MS Homo sapiens
256 PGRMC1 10857
Affinity Capture-MS Homo sapiens
257 THOC3  
Affinity Capture-MS Homo sapiens
258 PDCD2L 84306
Affinity Capture-MS Homo sapiens
259 HECTD3 79654
Affinity Capture-MS Homo sapiens
260 ASPSCR1 79058
Affinity Capture-MS Homo sapiens
261 MCL1 4170
Affinity Capture-MS Homo sapiens
262 GMPS 8833
Affinity Capture-MS Homo sapiens
263 KEAP1 9817
Affinity Capture-MS Homo sapiens
264 PHGDH 26227
Affinity Capture-MS Homo sapiens
265 BOP1 23246
Affinity Capture-MS Homo sapiens
266 KPNA6 23633
Affinity Capture-MS Homo sapiens
267 ARL8A 127829
Affinity Capture-MS Homo sapiens
268 TRIM65 201292
Affinity Capture-MS Homo sapiens
269 ATP6V1A 523
Affinity Capture-MS Homo sapiens
270 RPS15 6209
Affinity Capture-MS Homo sapiens
271 ANAPC1 64682
Affinity Capture-MS Homo sapiens
272 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
273 CCT2 10576
Affinity Capture-MS Homo sapiens
274 MAPK1 5594
Affinity Capture-MS Homo sapiens
275 SIRT1