Gene description for UFC1
Gene name ubiquitin-fold modifier conjugating enzyme 1
Gene symbol UFC1
Other names/aliases HSPC155
Species Homo sapiens
 Database cross references - UFC1
ExoCarta ExoCarta_51506
Entrez Gene 51506
HGNC 26941
MIM 610554
UniProt Q9Y3C8  
 UFC1 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for UFC1
Molecular Function
    protein binding GO:0005515 IPI
    UFM1 transferase activity GO:0071568 IDA
Biological Process
    response to endoplasmic reticulum stress GO:0034976 IDA
    protein K69-linked ufmylation GO:1990592 IDA
    protein ufmylation GO:0071569 IMP
Subcellular Localization
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified UFC1 in exosomes
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for UFC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CDK5RAP3  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which UFC1 is involved
No pathways found

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