Gene description for UBE2D3
Gene name ubiquitin-conjugating enzyme E2D 3
Gene symbol UBE2D3
Other names/aliases E2(17)KB3
UBC4/5
UBCH5C
Species Homo sapiens
 Database cross references - UBE2D3
ExoCarta ExoCarta_7323
Vesiclepedia VP_7323
Entrez Gene 7323
HGNC 12476
MIM 602963
UniProt P61077  
 UBE2D3 identified in exosomes derived from the following tissue/cell type
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Neuroblastoma cells 25944692    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Prostate cancer cells 25844599    
 Gene ontology annotations for UBE2D3
Molecular Function
    ubiquitin-protein transferase activity GO:0004842 IDA
    ubiquitin-protein transferase activity GO:0004842 TAS
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    ubiquitin protein ligase activity GO:0061630 IDA
    ubiquitin conjugating enzyme activity GO:0061631 IBA
    ubiquitin conjugating enzyme activity GO:0061631 IDA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 TAS
    protein polyubiquitination GO:0000209 IDA
    DNA repair GO:0006281 IEA
    ubiquitin-dependent protein catabolic process GO:0006511 IBA
    protein monoubiquitination GO:0006513 IDA
    apoptotic process GO:0006915 IEA
    protein ubiquitination GO:0016567 IDA
    negative regulation of BMP signaling pathway GO:0030514 TAS
    protein modification process GO:0036211 TAS
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IDA
    protein autoubiquitination GO:0051865 IDA
    protein K48-linked ubiquitination GO:0070936 IBA
    protein K48-linked ubiquitination GO:0070936 IDA
    protein K11-linked ubiquitination GO:0070979 IBA
    protein K11-linked ubiquitination GO:0070979 IDA
    protein K6-linked ubiquitination GO:0085020 IDA
    positive regulation of protein targeting to mitochondrion GO:1903955 HMP
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 TAS
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IEA
    endosome membrane GO:0010008 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified UBE2D3 in exosomes
1
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
4
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
5
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
6
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
7
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
 Protein-protein interactions for UBE2D3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SIAH1  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
2 TRAIP  
Reconstituted Complex Homo sapiens
3 Mdm2  
Reconstituted Complex Mus musculus
4 CDC34 997
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
5 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
6 ISG15 9636
Affinity Capture-Western Homo sapiens
7 PCGF5  
Reconstituted Complex Homo sapiens
8 XIAP  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
9 RNF122  
Reconstituted Complex Homo sapiens
10 FBXO7 25793
Reconstituted Complex Homo sapiens
11 SIAH2 6478
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
12 RNF167 26001
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
13 WWP1 11059
Reconstituted Complex Homo sapiens
14 MARCH7  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
15 TRIM35 23087
Two-hybrid Homo sapiens
16 TRIM2  
Two-hybrid Homo sapiens
17 RNF25 64320
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
18 MKRN3  
Two-hybrid Homo sapiens
19 SH3RF1  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
20 UBA1 7317
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
21 BRCA1 672
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
22 EPS15 2060
Biochemical Activity Homo sapiens
23 TRIM33 51592
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
24 UBC 7316
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
25 Rbx1  
Reconstituted Complex Mus musculus
26 VHL  
Reconstituted Complex Homo sapiens
27 TRIM55  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
28 MARCH3 115123
Two-hybrid Homo sapiens
29 MID1 4281
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
30 PSMD4 5710
Cross-Linking-MS (XL-MS) Homo sapiens
31 SYVN1 84447
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
32 HSPA1A 3303
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
33 RNF216  
Reconstituted Complex Homo sapiens
34 RFFL 117584
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
35 PCGF2 7703
Reconstituted Complex Homo sapiens
36 RCHY1  
Reconstituted Complex Homo sapiens
37 Aurkb  
Reconstituted Complex Mus musculus
38 PJA1  
Reconstituted Complex Homo sapiens
39 TRIM28 10155
Reconstituted Complex Homo sapiens
40 DTX3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
41 RNF5  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
42 MCM2 4171
Affinity Capture-MS Homo sapiens
43 POLL  
Biochemical Activity Homo sapiens
44 MYLIP  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
45 RNF8  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
46 FZR1  
Reconstituted Complex Homo sapiens
47 TRIM50  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
48 TRIM54  
Reconstituted Complex Homo sapiens
49 FBXW8 26259
Reconstituted Complex Homo sapiens
50 MARCH5  
Reconstituted Complex Homo sapiens
51 DDX58 23586
Biochemical Activity Homo sapiens
52 ANAPC11  
Reconstituted Complex Homo sapiens
53 MID2 11043
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
54 LRSAM1 90678
Two-hybrid Homo sapiens
55 HERC2 8924
Reconstituted Complex Homo sapiens
56 TRIM26 7726
Two-hybrid Homo sapiens
57 BIRC3 330
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
58 MSL2  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
59 TERT  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
60 POLM  
Biochemical Activity Homo sapiens
61 Ube4b  
Reconstituted Complex Mus musculus
62 TRIM25 7706
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
63 RNF126  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
64 BTRC 8945
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
65 ARIH2 10425
Two-hybrid Homo sapiens
66 ATXN3 4287
Biochemical Activity Homo sapiens
67 USP7 7874
Biochemical Activity Homo sapiens
68 NEDD8 4738
Co-fractionation Homo sapiens
69 NEDD4 4734
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
70 BFAR  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
71 RNF11 26994
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
72 RNF115  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
73 TRIM8  
Two-hybrid Homo sapiens
74 RNF181  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
75 HSP90AB1 3326
Biochemical Activity Homo sapiens
76 RABGEF1 27342
Reconstituted Complex Homo sapiens
77 STAM2 10254
Biochemical Activity Homo sapiens
78 RNF41  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
79 RNF165  
Two-hybrid Homo sapiens
80 MIB1 57534
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
81 UBE4B 10277
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
82 RNF4 6047
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
83 TRIM7  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
84 TRIM58 25893
Reconstituted Complex Homo sapiens
85 RBX1 9978
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
86 KLHL3  
Reconstituted Complex Homo sapiens
87 CUL4B 8450
Reconstituted Complex Homo sapiens
88 PARK2  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
89 UBE2D4  
Affinity Capture-MS Homo sapiens
90 CADPS2  
Two-hybrid Homo sapiens
91 AMFR 267
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
92 HIST1H2AG 8969
Cross-Linking-MS (XL-MS) Homo sapiens
93 DTX1  
Two-hybrid Homo sapiens
94 TUBA1A 7846
Two-hybrid Homo sapiens
95 STAU1 6780
Two-hybrid Homo sapiens
96 CBL 867
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
97 CNOT4 4850
Two-hybrid Homo sapiens
98 RNF146  
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
99 RNF213 57674
Reconstituted Complex Homo sapiens
100 ZNRF2 223082
Two-hybrid Homo sapiens
101 TBC1D32 221322
Proximity Label-MS Homo sapiens
102 UBASH3B 84959
Biochemical Activity Homo sapiens
103 UBR5 51366
Reconstituted Complex Homo sapiens
104 PDCD5 9141
Two-hybrid Homo sapiens
105 SLC25A5 292
Cross-Linking-MS (XL-MS) Homo sapiens
106 BIRC8  
Two-hybrid Homo sapiens
107 BARD1 580
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
108 RNF168  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
109 RNF166  
Two-hybrid Homo sapiens
110 FBXW10  
Biochemical Activity Homo sapiens
111 DTX2 113878
Two-hybrid Homo sapiens
112 F12  
Reconstituted Complex Homo sapiens
113 TRIM32 22954
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
114 TRIM11  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
115 NFKBIA  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
116 RPLP1 6176
Two-hybrid Homo sapiens