Gene description for RNF167
Gene name ring finger protein 167
Gene symbol RNF167
Other names/aliases 5730408C10Rik
LP2254
RING105
Species Homo sapiens
 Database cross references - RNF167
ExoCarta ExoCarta_26001
Entrez Gene 26001
HGNC 24544
MIM 610431
UniProt Q9H6Y7  
 RNF167 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for RNF167
Molecular Function
    ligase activity GO:0016874 IEA
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 IEA
    ubiquitin-protein transferase activity GO:0004842 IDA
Biological Process
    negative regulation of cell cycle GO:0045786 IMP
    protein polyubiquitination GO:0000209 IDA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    endomembrane system GO:0012505 IEA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified RNF167 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for RNF167
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HSPC128  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which RNF167 is involved
No pathways found





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