Gene description for TMPRSS11B
Gene name transmembrane protease, serine 11B
Gene symbol TMPRSS11B
Other names/aliases -
Species Homo sapiens
 Database cross references - TMPRSS11B
ExoCarta ExoCarta_132724
Entrez Gene 132724
HGNC 25398
UniProt Q86T26  
 TMPRSS11B identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for TMPRSS11B
Molecular Function
    serine-type peptidase activity GO:0008236 IDA
    serine-type endopeptidase activity GO:0004252 IEA
Biological Process
    biological_process GO:0008150 ND
    proteolysis GO:0006508 IEA
Subcellular Localization
    plasma membrane GO:0005886 IDA
    integral component of plasma membrane GO:0005887 IEA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified TMPRSS11B in exosomes
1
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for TMPRSS11B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TMPRSS11B is involved
No pathways found





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