Gene description for LMF1
Gene name lipase maturation factor 1
Gene symbol LMF1
Other names/aliases C16orf26
HMFN1876
JFP11
TMEM112
TMEM112A
Species Homo sapiens
 Database cross references - LMF1
ExoCarta ExoCarta_64788
Vesiclepedia VP_64788
Entrez Gene 64788
HGNC 14154
MIM 611761
UniProt Q96S06  
 LMF1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for LMF1
Biological Process
    triglyceride metabolic process GO:0006641 IMP
    protein maturation GO:0051604 IBA
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 TAS
 Experiment description of studies that identified LMF1 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for LMF1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 BRINP2  
Affinity Capture-MS Homo sapiens
2 TOR3A 64222
Affinity Capture-MS Homo sapiens
3 LAT 27040
Affinity Capture-MS Homo sapiens
4 TMEM30A 55754
Affinity Capture-MS Homo sapiens
5 NUDT9 53343
Affinity Capture-MS Homo sapiens
6 KLK8 11202
Affinity Capture-MS Homo sapiens
7 CD3D 915
Affinity Capture-MS Homo sapiens
8 GP9 2815
Affinity Capture-MS Homo sapiens
9 TMPRSS11B 132724
Affinity Capture-MS Homo sapiens
10 TAZ  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 ENPP6 133121
Affinity Capture-MS Homo sapiens
12 HTR3C  
Affinity Capture-MS Homo sapiens
13 WNT4  
Affinity Capture-MS Homo sapiens
14 HS2ST1 9653
Affinity Capture-MS Homo sapiens
15 ATP1B4  
Affinity Capture-MS Homo sapiens
16 ITGB8 3696
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 SERPINB11  
Affinity Capture-MS Homo sapiens
18 GCNT2 2651
Affinity Capture-MS Homo sapiens
19 A4GNT  
Affinity Capture-MS Homo sapiens
20 LYZL6  
Affinity Capture-MS Homo sapiens
21 SFTPC  
Affinity Capture-MS Homo sapiens
22 SEZ6  
Affinity Capture-MS Homo sapiens
23 OGFOD3 79701
Affinity Capture-MS Homo sapiens
24 CHRNB2  
Affinity Capture-MS Homo sapiens
25 C12orf49  
Affinity Capture-MS Homo sapiens
26 GP5 2814
Affinity Capture-MS Homo sapiens
27 CHRNB4  
Affinity Capture-MS Homo sapiens
28 CSN1S1 1446
Affinity Capture-MS Homo sapiens
29 CHST8 64377
Affinity Capture-MS Homo sapiens
30 UGT1A7 54577
Affinity Capture-MS Homo sapiens
31 DCT 1638
Affinity Capture-MS Homo sapiens
32 WNT5A 7474
Affinity Capture-MS Homo sapiens
33 CLEC2B  
Affinity Capture-MS Homo sapiens
34 HLA-G 3135
Affinity Capture-MS Homo sapiens
35 TRAV20  
Affinity Capture-MS Homo sapiens
36 LYPD6  
Affinity Capture-MS Homo sapiens
37 NDST3  
Affinity Capture-MS Homo sapiens
38 FUT9  
Affinity Capture-MS Homo sapiens
39 NXPH3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 B4GALT3 8703
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 ADAM18  
Affinity Capture-MS Homo sapiens
42 SPINT2 10653
Affinity Capture-MS Homo sapiens
43 CLEC4E  
Affinity Capture-MS Homo sapiens
44 SLC22A9  
Affinity Capture-MS Homo sapiens
45 NXPE2  
Affinity Capture-MS Homo sapiens
46 HLA-C 3107
Affinity Capture-MS Homo sapiens
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