Gene description for GP5
Gene name glycoprotein V (platelet)
Gene symbol GP5
Other names/aliases CD42d
GPV
Species Homo sapiens
 Database cross references - GP5
ExoCarta ExoCarta_2814
Vesiclepedia VP_2814
Entrez Gene 2814
HGNC 4443
MIM 173511
UniProt P40197  
 GP5 identified in exosomes derived from the following tissue/cell type
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
 Gene ontology annotations for GP5
Molecular Function
    collagen binding GO:0005518 IEA
Biological Process
    platelet activation GO:0030168 TAS
    cell-matrix adhesion GO:0007160 IEA
    blood coagulation GO:0007596 TAS
    cell adhesion GO:0007155 NAS
    negative regulation of platelet activation GO:0010544 IEA
    blood coagulation, intrinsic pathway GO:0007597 TAS
Subcellular Localization
    plasma membrane GO:0005886 TAS
    extracellular exosome GO:0070062 IDA
    integral component of plasma membrane GO:0005887 TAS
 Experiment description of studies that identified GP5 in exosomes
1
Experiment ID 231
MISEV standards
EV Biophysical techniques
Alix|CD63|CD9
EV Enriched markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 232
MISEV standards
EV Biophysical techniques
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 233
MISEV standards
EV Biophysical techniques
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GP5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GP1BA 2811
Invivo Homo sapiens
View the network image/svg+xml



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