Gene description for DNAJC11
Gene name DnaJ (Hsp40) homolog, subfamily C, member 11
Gene symbol DNAJC11
Other names/aliases dJ126A5.1
Species Homo sapiens
 Database cross references - DNAJC11
ExoCarta ExoCarta_55735
Entrez Gene 55735
HGNC 25570
MIM 614827
UniProt Q9NVH1  
 DNAJC11 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for DNAJC11
Molecular Function
    protein binding GO:0005515 IPI
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    mitochondrial inner membrane GO:0005743 IEA
 Experiment description of studies that identified DNAJC11 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for DNAJC11
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DNAJC11 is involved
No pathways found





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