Gene description for RPS6KA5
Gene name	ribosomal protein S6 kinase, 90kDa, polypeptide 5
Gene symbol	RPS6KA5
Other names/aliases	MSK1 MSPK1 RLPK
Species	Homo sapiens
Database cross references - RPS6KA5
ExoCarta	ExoCarta_9252
Vesiclepedia	VP_9252
Entrez Gene	9252
HGNC	10434
MIM	603607
UniProt	O75582
RPS6KA5 identified in sEVs derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for RPS6KA5

Molecular Function     magnesium ion binding GO:0000287 IEA     protein serine/threonine kinase activity GO:0004674 IBA     protein serine/threonine kinase activity GO:0004674 IDA     protein serine/threonine kinase activity GO:0004674 TAS     3-phosphoinositide-dependent protein kinase activity GO:0004676 IEA     DNA-dependent protein kinase activity GO:0004677 IEA     AMP-activated protein kinase activity GO:0004679 IEA     eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 IEA     ribosomal protein S6 kinase activity GO:0004711 IEA     protein tyrosine kinase activity GO:0004713 IDA     protein binding GO:0005515 IPI     ATP binding GO:0005524 IDA     histone H3S10 kinase activity GO:0035175 IMP     histone H3T11 kinase activity GO:0035402 IEA     histone H3T6 kinase activity GO:0035403 IEA     histone H2AXS139 kinase activity GO:0035979 IEA     histone H3S28 kinase activity GO:0044022 IMP     histone H4S1 kinase activity GO:0044023 IEA     histone H2AS1 kinase activity GO:0044024 IDA     histone H2BS14 kinase activity GO:0044025 IEA     histone H3T3 kinase activity GO:0072354 IEA     histone H2AS121 kinase activity GO:0072371 IEA     Rho-dependent protein serine/threonine kinase activity GO:0072518 IEA     protein serine kinase activity GO:0106310 IEA     histone H2BS36 kinase activity GO:0140823 IEA     histone H3S57 kinase activity GO:0140855 IEA     histone H3T45 kinase activity GO:0140857 IEA     histone H2AT120 kinase activity GO:1990244 IEA Biological Process     negative regulation of cytokine production GO:0001818 TAS     chromatin remodeling GO:0006338 IEA     regulation of DNA-templated transcription GO:0006355 IBA     regulation of DNA-templated transcription GO:0006355 IDA     regulation of DNA-templated transcription GO:0006355 IMP     protein phosphorylation GO:0006468 IDA     inflammatory response GO:0006954 IEA     axon guidance GO:0007411 TAS     positive regulation of CREB transcription factor activity GO:0032793 TAS     intracellular signal transduction GO:0035556 IDA     TORC1 signaling GO:0038202 IBA     post-translational protein modification GO:0043687 IDA     post-translational protein modification GO:0043687 IMP     negative regulation of DNA-templated transcription GO:0045892 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IMP     positive regulation of NF-kappaB transcription factor activity GO:0051092 IMP     interleukin-1-mediated signaling pathway GO:0070498 IMP     regulation of postsynapse organization GO:0099175 IEA Subcellular Localization     nucleus GO:0005634 IDA     nucleus GO:0005634 IMP     nucleoplasm GO:0005654 IBA     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 TAS     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 IDA