Gene description for RPS6KA5
Gene name	ribosomal protein S6 kinase, 90kDa, polypeptide 5
Gene symbol	RPS6KA5
Other names/aliases	MSK1 MSPK1 RLPK
Species	Homo sapiens
Database cross references - RPS6KA5
ExoCarta	ExoCarta_9252
Entrez Gene	9252
HGNC	10434
MIM	603607
UniProt	O75582
RPS6KA5 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for RPS6KA5

Molecular Function     protein serine/threonine kinase activity GO:0004674 IMP     protein kinase activity GO:0004672 IDA     magnesium ion binding GO:0000287 IEA     protein binding GO:0005515 IPI     ATP binding GO:0005524 IDA Biological Process     intracellular signal transduction GO:0035556 IDA     protein phosphorylation GO:0006468 IDA     positive regulation of histone phosphorylation GO:0033129 IMP     positive regulation of CREB transcription factor activity GO:0032793 TAS     axon guidance GO:0007411 TAS     toll-like receptor 4 signaling pathway GO:0034142 TAS     positive regulation of histone acetylation GO:0035066 IMP     negative regulation of transcription, DNA-templated GO:0045892 IDA     toll-like receptor 3 signaling pathway GO:0034138 TAS     inflammatory response GO:0006954 IEA     innate immune response GO:0045087 TAS     stimulatory C-type lectin receptor signaling pathway GO:0002223 TAS     negative regulation of cytokine production GO:0001818 TAS     MyD88-dependent toll-like receptor signaling pathway GO:0002755 TAS     histone H3-S28 phosphorylation GO:0043988 IMP     toll-like receptor 10 signaling pathway GO:0034166 TAS     regulation of transcription, DNA-templated GO:0006355 IMP     toll-like receptor signaling pathway GO:0002224 TAS     MyD88-independent toll-like receptor signaling pathway GO:0002756 TAS     epidermal growth factor receptor signaling pathway GO:0007173 TAS     toll-like receptor 2 signaling pathway GO:0034134 TAS     toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 TAS     toll-like receptor 9 signaling pathway GO:0034162 TAS     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IMP     interleukin-1-mediated signaling pathway GO:0070498 IMP     toll-like receptor 5 signaling pathway GO:0034146 TAS     histone H2A-S1 phosphorylation GO:0043990 IDA     stress-activated MAPK cascade GO:0051403 TAS     TRIF-dependent toll-like receptor signaling pathway GO:0035666 TAS     histone phosphorylation GO:0016572 TAS     histone H3-S10 phosphorylation GO:0043987 IMP     toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 TAS     positive regulation of NF-kappaB transcription factor activity GO:0051092 IMP     neurotrophin TRK receptor signaling pathway GO:0048011 TAS Subcellular Localization     nucleoplasm GO:0005654 TAS     cytoplasm GO:0005737 IDA     nucleus GO:0005634 IMP