Gene description for IMMT
Gene name inner membrane protein, mitochondrial
Gene symbol IMMT
Other names/aliases HMP
MINOS2
P87
P87/89
P89
PIG4
PIG52
Species Homo sapiens
 Database cross references - IMMT
ExoCarta ExoCarta_10989
Entrez Gene 10989
HGNC 6047
MIM 600378
UniProt Q16891  
 IMMT identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for IMMT
Molecular Function
    protein binding GO:0005515 IPI
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    mitochondrial calcium ion homeostasis GO:0051560 IEA
    response to cold GO:0009409 IEA
    biological_process GO:0008150 ND
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrion GO:0005739 IDA
    membrane GO:0016020 IDA
 Experiment description of studies that identified IMMT in exosomes
1
Experiment ID 191
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD81|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IMMT
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SDHAF2 54949
Two-hybrid Homo sapiens
2 NIPSNAP3A  
Two-hybrid Homo sapiens
3 MRPL44  
Two-hybrid Homo sapiens
4 PRRC2A 7916
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
5 STX5A  
Two-hybrid Homo sapiens
6 PPOX  
Two-hybrid Homo sapiens
7 CHD3  
Two-hybrid Homo sapiens
8 ASCC2  
Two-hybrid Homo sapiens
9 TXNDC9  
Two-hybrid Homo sapiens
10 PFDN1  
Two-hybrid Homo sapiens
11 STMN4  
Two-hybrid Homo sapiens
12 SNAPAP  
Two-hybrid Homo sapiens
13 FTS  
Two-hybrid Homo sapiens
14 CSTF2  
Two-hybrid Homo sapiens
15 DKFZp762E1312  
Two-hybrid Homo sapiens
16 C16orf24  
Two-hybrid Homo sapiens
17 CCT5 22948
Two-hybrid Homo sapiens
18 LYPLA3  
Two-hybrid Homo sapiens
19 SRRT 51593
Two-hybrid Homo sapiens
20 NDUFB9  
Two-hybrid Homo sapiens
21 C10orf88  
Two-hybrid Homo sapiens
22 KDM1A 23028
Two-hybrid Homo sapiens
23 FUBP1 8880
Invitro Homo sapiens
24 BAG6 7917
Two-hybrid Homo sapiens
25 KIF22  
Two-hybrid Homo sapiens
26 BMI1  
Two-hybrid Homo sapiens
27 ARMCX3 51566
Two-hybrid Homo sapiens
28 RER1 11079
Two-hybrid Homo sapiens
29 HSPC065  
Two-hybrid Homo sapiens
30 ECSIT 51295
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which IMMT is involved
No pathways found





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