Gene description for SLC25A1
Gene name
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
Gene symbol
SLC25A1
Other names/aliases
CTP D2L2AD SEA SLC20A3
Species
Homo sapiens
Database cross references - SLC25A1
ExoCarta
ExoCarta_6576
Entrez Gene
6576
HGNC
10979
MIM
190315
UniProt
P53007
SLC25A1 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells
20124223
Urine
19056867
Gene ontology annotations for SLC25A1
Experiment description of studies that identified SLC25A1 in exosomes
1
Experiment ID
191
ISEV standards
✘
EV Biophysical techniques
✔
Alix
EV Cytosolic markers
✔
CD81|CD9
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20124223
Organism
Homo sapiens
Experiment description
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors
Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name
Mol Cell Proteomics
Publication year
2010
Sample
Squamous carcinoma cells
Sample name
Squamous carcinoma cell (A431)
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
63
ISEV standards
✘
EV Biophysical techniques
✘
EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19056867
Organism
Homo sapiens
Experiment description
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name
JASN
Publication year
2009
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
Protein-protein interactions for SLC25A1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
VCL
7414
Affinity Capture-MS
Homo sapiens
2
MAGED1
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which SLC25A1 is involved