Gene description for PELO
Gene name pelota homolog (Drosophila)
Gene symbol PELO
Other names/aliases CGI-17
Species Homo sapiens
 Database cross references - PELO
ExoCarta ExoCarta_53918
Entrez Gene 53918
HGNC 8829
MIM 605757
UniProt Q9BRX2  
 PELO identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for PELO
Molecular Function
    metal ion binding GO:0046872 IEA
    endonuclease activity GO:0004519 IEA
    protein binding GO:0005515 IPI
Biological Process
    cell proliferation GO:0008283 IEA
    cell cycle GO:0007049 IEA
    nuclear-transcribed mRNA catabolic process, no-go decay GO:0070966 IEA
    chromosome organization GO:0051276 IEA
    nucleic acid phosphodiester bond hydrolysis GO:0090305 IEA
    cell division GO:0051301 IEA
    nuclear-transcribed mRNA catabolic process, non-stop decay GO:0070481 IEA
    RNA surveillance GO:0071025 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified PELO in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PELO
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SLC25A12  
Affinity Capture-MS Homo sapiens
2 HACD3 51495
Affinity Capture-MS Homo sapiens
3 MCM7 4176
Affinity Capture-MS Homo sapiens
4 AIFM1  
Affinity Capture-MS Homo sapiens
5 ABCD3 5825
Affinity Capture-MS Homo sapiens
6 TIMM50 92609
Affinity Capture-MS Homo sapiens
7 RUVBL1 8607
Affinity Capture-MS Homo sapiens
8 MYO1D 4642
Affinity Capture-MS Homo sapiens
9 HEATR1 55127
Affinity Capture-MS Homo sapiens
10 FANCI 55215
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PELO is involved
No pathways found

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