Gene description for SREBF1
Gene name	sterol regulatory element binding transcription factor 1
Gene symbol	SREBF1
Other names/aliases	SREBP-1c SREBP1 bHLHd1
Species	Homo sapiens
Database cross references - SREBF1
ExoCarta	ExoCarta_6720
Entrez Gene	6720
HGNC	11289
MIM	184756
UniProt	P36956
SREBF1 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for SREBF1

Molecular Function     sterol response element binding GO:0032810 IDA     protein binding GO:0005515 IPI     DNA binding GO:0003677 ISS     protein kinase binding GO:0019901 IEA     protein complex binding GO:0032403 IEA     protein dimerization activity GO:0046983 IEA     sequence-specific DNA binding transcription factor activity GO:0003700 IDA     sequence-specific DNA binding GO:0043565 IEA     chromatin binding GO:0003682 IEA Biological Process     response to drug GO:0042493 IEA     circadian rhythm GO:0007623 TAS     regulation of protein targeting to mitochondrion GO:1903214 IMP     regulation of fatty acid metabolic process GO:0019217 IEA     positive regulation of histone deacetylation GO:0031065 IEA     response to progesterone GO:0032570 IEA     regulation of protein stability GO:0031647 IMP     response to glucose GO:0009749 IEA     aging GO:0007568 IEA     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IEA     lipid biosynthetic process GO:0008610 ISS     response to food GO:0032094 IEA     transcription, DNA-templated GO:0006351 IEA     cellular response to fatty acid GO:0071398 IEA     negative regulation of insulin secretion GO:0046676 IEA     response to retinoic acid GO:0032526 IEA     regulation of mitochondrion degradation GO:1903146 IMP     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IEA     regulation of heart rate by chemical signal GO:0003062 IEA     response to glucagon GO:0033762 IEA     positive regulation of triglyceride biosynthetic process GO:0010867 ISS     small molecule metabolic process GO:0044281 TAS     cholesterol metabolic process GO:0008203 IEA     insulin receptor signaling pathway GO:0008286 IEA     response to cAMP GO:0051591 IEA     lipid metabolic process GO:0006629 TAS     positive regulation of cholesterol biosynthetic process GO:0045542 IEA     lung development GO:0030324 IEA     cellular response to starvation GO:0009267 ISS     regulation of transcription from RNA polymerase II promoter GO:0006357 TAS Subcellular Localization     cytosol GO:0005829 TAS     cytoplasm GO:0005737 ISS     endoplasmic reticulum membrane GO:0005789 TAS     nucleoplasm GO:0005654 TAS     integral component of membrane GO:0016021 IEA     Golgi membrane GO:0000139 TAS     endoplasmic reticulum GO:0005783 IDA     nucleus GO:0005634 IDA     nuclear envelope GO:0005635 TAS     ER to Golgi transport vesicle membrane GO:0012507 IEA     protein complex GO:0043234 IEA