Gene description for TSC2
Gene name tuberous sclerosis 2
Gene symbol TSC2
Other names/aliases LAM
PPP1R160
TSC4
Species Homo sapiens
 Database cross references - TSC2
ExoCarta ExoCarta_7249
Vesiclepedia VP_7249
Entrez Gene 7249
HGNC 12363
MIM 191092
UniProt P49815  
 TSC2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for TSC2
Molecular Function
    GTPase activator activity GO:0005096 IBA
    GTPase activator activity GO:0005096 IDA
    protein binding GO:0005515 IPI
    phosphatase binding GO:0019902 IDA
    small GTPase binding GO:0031267 IPI
    protein homodimerization activity GO:0042803 IPI
    Hsp90 protein binding GO:0051879 IPI
Biological Process
    neural tube closure GO:0001843 ISS
    negative regulation of protein kinase activity GO:0006469 ISS
    protein import into nucleus GO:0006606 ISS
    endocytosis GO:0006897 TAS
    heart development GO:0007507 ISS
    protein localization GO:0008104 ISS
    negative regulation of cell population proliferation GO:0008285 ISS
    cellular response to starvation GO:0009267 IDA
    vesicle-mediated transport GO:0016192 TAS
    positive regulation of macroautophagy GO:0016239 IGI
    regulation of endocytosis GO:0030100 ISS
    negative regulation of Wnt signaling pathway GO:0030178 IBA
    negative regulation of TOR signaling GO:0032007 IBA
    negative regulation of TOR signaling GO:0032007 IDA
    negative regulation of TOR signaling GO:0032007 IGI
    anoikis GO:0043276 IGI
    phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0043491 ISS
    regulation of insulin receptor signaling pathway GO:0046626 ISS
    negative regulation of insulin receptor signaling pathway GO:0046627 IBA
    insulin-like growth factor receptor signaling pathway GO:0048009 ISS
    positive chemotaxis GO:0050918 ISS
    regulation of small GTPase mediated signal transduction GO:0051056 IEA
    regulation of cell cycle GO:0051726 IBA
    negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051898 IBA
    negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051898 ISS
    negative regulation of mitophagy GO:1901525 NAS
    negative regulation of TORC1 signaling GO:1904262 IDA
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 IDA
    lysosome GO:0005764 IDA
    lysosomal membrane GO:0005765 IDA
    Golgi apparatus GO:0005794 IDA
    Golgi apparatus GO:0005794 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    postsynaptic density GO:0014069 EXP
    postsynaptic density GO:0014069 IDA
    membrane GO:0016020 IDA
    TSC1-TSC2 complex GO:0033596 IBA
    TSC1-TSC2 complex GO:0033596 IDA
    TSC1-TSC2 complex GO:0033596 IPI
    perinuclear region of cytoplasm GO:0048471 IDA
 Experiment description of studies that identified TSC2 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 193
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
PHB
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 194
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 195
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TSC2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PRKAA1 5562
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
2 TK1 7083
Two-hybrid Homo sapiens
3 LAMP3  
Proximity Label-MS Homo sapiens
4 HCST  
Affinity Capture-MS Homo sapiens
5 DAPK1 1612
Affinity Capture-Western Homo sapiens
6 YWHAE 7531
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 P4HA2 8974
Affinity Capture-MS Homo sapiens
8 MDFI  
Two-hybrid Homo sapiens
9 UBE3A 7337
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
10 RRAGD 58528
Affinity Capture-Western Homo sapiens
11 LAMP2 3920
Proximity Label-MS Homo sapiens
12 CALM1 801
Protein-peptide Homo sapiens
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
13 TRIM55  
Two-hybrid Homo sapiens
14 CBY1  
Affinity Capture-MS Homo sapiens
15 PNKD  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 CD83  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 Tbc1d7  
Affinity Capture-MS Mus musculus
18 RHEB 6009
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
19 DYRK1A 1859
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 POU5F1  
Affinity Capture-MS Homo sapiens
21 YWHAG 7532
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 SIRT1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
23 SEMA4C 54910
Affinity Capture-MS Homo sapiens
24 APEX1 328
Affinity Capture-RNA Homo sapiens
25 DGCR2 9993
Affinity Capture-MS Homo sapiens
26 YWHAH 7533
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 P4HA3 283208
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 FBXW5  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
29 GPR17 2840
Affinity Capture-MS Homo sapiens
30 GSK3B 2932
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
31 LAMTOR1 55004
Proximity Label-MS Homo sapiens
32 AKT1 207
Affinity Capture-Western Homo sapiens
33 YWHAB 7529
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
34 NUP155 9631
Proximity Label-MS Homo sapiens
35 MAPK1 5594
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
36 PAM 5066
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Two-hybrid Homo sapiens
37 PPP1CA 5499
Reconstituted Complex Homo sapiens
38 FAM96A  
Affinity Capture-MS Homo sapiens
39 CD79B 974
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 CTDP1 9150
Affinity Capture-MS Homo sapiens
41 RALA 5898
Affinity Capture-Western Homo sapiens
42 RRAGB 10325
Affinity Capture-Western Homo sapiens
43 MPL 4352
Affinity Capture-MS Homo sapiens
44 TMED5 50999
Affinity Capture-MS Homo sapiens
45 ARRDC2  
Affinity Capture-MS Homo sapiens
46 NTRK1 4914
Affinity Capture-MS Homo sapiens
47 SPERT  
Two-hybrid Homo sapiens
48 GPR182  
Affinity Capture-MS Homo sapiens
49 RAP1A 5906
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
50 YWHAQ 10971
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
51 SREBF1 6720
Negative Genetic Homo sapiens
52 TRIM63  
Two-hybrid Homo sapiens
53 RPS6KA1 6195
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
54 CBFB 865
Affinity Capture-MS Homo sapiens
55 PTPN11 5781
Reconstituted Complex Homo sapiens
56 CYB5B 80777
Affinity Capture-MS Homo sapiens
57 SIGLECL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 RRAGA 10670
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
59 CIAO1 9391
Affinity Capture-MS Homo sapiens
60 RAB5A 5868
Co-purification Homo sapiens
61 COL20A1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 NPTN 27020
Affinity Capture-MS Homo sapiens
63 FOXO1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
64 CUL3 8452
Affinity Capture-MS Homo sapiens
65 YWHAZ 7534
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
66 PTK2 5747
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
67 METTL21B  
Affinity Capture-MS Homo sapiens
68 MORF4L1  
Affinity Capture-MS Homo sapiens
69 DUSP16  
Affinity Capture-MS Homo sapiens
70 RIPK4  
Affinity Capture-MS Homo sapiens
71 OCIAD1 54940
Affinity Capture-MS Homo sapiens
72 CD226 10666
Affinity Capture-MS Homo sapiens
73 ZP2  
Affinity Capture-MS Homo sapiens
74 MUL1  
Affinity Capture-MS Homo sapiens
75 C3orf18  
Affinity Capture-MS Homo sapiens
76 HECW2  
Affinity Capture-MS Homo sapiens
77 RAB9A 9367
Proximity Label-MS Homo sapiens
78 TIGAR 57103
Co-fractionation Homo sapiens
79 TMEM9 252839
Affinity Capture-MS Homo sapiens
80 OTULIN 90268
Affinity Capture-MS Homo sapiens
81 HAX1  
Proximity Label-MS Homo sapiens
82 CDKN1B 1027
Affinity Capture-Western Homo sapiens
83 CCND1 595
Affinity Capture-Western Homo sapiens
84 TSC2 7249
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 RRAGC 64121
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
86 HUWE1 10075
Affinity Capture-MS Homo sapiens
87 TSPAN10 83882
Affinity Capture-MS Homo sapiens
88 HERC1 8925
Affinity Capture-Western Homo sapiens
89 GYPA  
Affinity Capture-MS Homo sapiens
90 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
91 PRKCSH 5589
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 ALDH3A2 224
Affinity Capture-MS Homo sapiens
93 CCND2  
Affinity Capture-Western Homo sapiens
94 GRB2 2885
Two-hybrid Homo sapiens
95 OPALIN  
Affinity Capture-MS Homo sapiens
96 TBC1D7  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
97 PIN1 5300
Two-hybrid Homo sapiens
98 Tsc1  
Affinity Capture-MS Mus musculus
99 RP2 6102
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 EDEM1  
Affinity Capture-MS Homo sapiens
101 EFNB1 1947
Affinity Capture-MS Homo sapiens
102 RUVBL2 10856
Affinity Capture-MS Homo sapiens
103 TSC1 7248
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
104 FASN 2194
Negative Genetic Homo sapiens
105 AXIN1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
106 NEK1  
Two-hybrid Homo sapiens
107 ESR1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
108 PPP4R1L  
Affinity Capture-MS Homo sapiens
109 FAM221B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 SUPT6H 6830
Reconstituted Complex Homo sapiens
111 RAB7A 7879
Proximity Label-MS Homo sapiens
112 WDR92 116143
Affinity Capture-MS Homo sapiens
113 STK11 6794
Negative Genetic Homo sapiens
114 C9orf72  
Affinity Capture-MS Homo sapiens
115 MEN1 4221
Affinity Capture-MS Homo sapiens
116 SPINT2 10653
Affinity Capture-MS Homo sapiens
117 DNAI2  
Affinity Capture-MS Homo sapiens
118 CAV1 857
Co-purification Homo sapiens
119 LNX1  
Two-hybrid Homo sapiens
120 CCND3  
Affinity Capture-Western Homo sapiens
View the network image/svg+xml



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