Gene description for CD79B
Gene name CD79b molecule, immunoglobulin-associated beta
Gene symbol CD79B
Other names/aliases AGM6
B29
IGB
Species Homo sapiens
 Database cross references - CD79B
ExoCarta ExoCarta_974
Vesiclepedia VP_974
Entrez Gene 974
HGNC 1699
MIM 147245
UniProt P40259  
 CD79B identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
 Gene ontology annotations for CD79B
Molecular Function
    transmembrane signaling receptor activity GO:0004888 IEA
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IDA
    identical protein binding GO:0042802 IPI
Biological Process
    adaptive immune response GO:0002250 IEA
    immune response GO:0006955 TAS
    signal transduction GO:0007165 TAS
    B cell differentiation GO:0030183 IBA
    B cell receptor signaling pathway GO:0050853 IBA
Subcellular Localization
    plasma membrane GO:0005886 TAS
    external side of plasma membrane GO:0009897 IBA
    B cell receptor complex GO:0019815 IBA
    B cell receptor complex GO:0019815 IDA
    extracellular exosome GO:0070062 HDA
    IgM B cell receptor complex GO:0071755 IDA
 Experiment description of studies that identified CD79B in sEVs
1
Experiment ID 80
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 81
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
 Protein-protein interactions for CD79B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DPY19L1 23333
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 INTS4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 LGR4 55366
Affinity Capture-MS Homo sapiens
4 MFAP3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 TSC2 7249
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 NUP188 23511
Affinity Capture-MS Homo sapiens
7 CCDC132 55610
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 ATP13A2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 MAN1B1 11253
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 GRAMD1A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 CD79A  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
12 PDE3B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 LTN1 26046
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 FAM20B 9917
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 PI4KA 5297
Affinity Capture-MS Homo sapiens
16 VANGL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 ABCA3 21
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 SLC25A14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 B3GNT2 10678
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 TRPM4 54795
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 ZRANB3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 D2HGDH 728294
Affinity Capture-MS Homo sapiens
23 FAM8A1 51439
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 SYK 6850
Reconstituted Complex Homo sapiens
25 PNPLA6 10908
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 SLC12A6 9990
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 ACVR2B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 HELLS 3070
Affinity Capture-MS Homo sapiens
29 C3orf52  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 SLC30A5 64924
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 TMTC4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 ATG16L1 55054
Affinity Capture-MS Homo sapiens
33 SLC25A25  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 TUBA1A 7846
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 ARFGEF2 10564
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 ERBB2 2064
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 FGFR1 2260
Affinity Capture-MS Homo sapiens
38 PTPRC 5788
Affinity Capture-Western Homo sapiens
39 MELK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 GOLIM4 27333
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 EXTL3 2137
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 AP3M1 26985
Affinity Capture-MS Homo sapiens
43 ATP8B2 57198
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 NF1 4763
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 RUFY1 80230
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 VPS51 738
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 NLRX1 79671
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 TUBA1C 84790
Affinity Capture-MS Homo sapiens
49 SREBF2 6721
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 CYBA 1535
Affinity Capture-MS Homo sapiens
51 INTS7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 MICU1 10367
Affinity Capture-MS Homo sapiens
53 C17orf62 79415
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 GOLGA5 9950
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 SGK3 23678
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 STAM 8027
Affinity Capture-Western Homo sapiens
57 HEATR6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 WDFY3 23001
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 FAM189B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 PLAA 9373
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 HUS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 CXCR4 7852
Affinity Capture-MS Homo sapiens
63 POLE2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 TARBP1 6894
Affinity Capture-MS Homo sapiens
65 POMK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 SLC30A6 55676
Affinity Capture-MS Homo sapiens
67 MYO19  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 ITPRIP  
Affinity Capture-MS Homo sapiens
69 RABGAP1 23637
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 RIPK4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 SLC25A23  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 C17orf80 55028
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 BLK 640
Affinity Capture-Western Homo sapiens
74 TUBA4A 7277
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 BIRC6 57448
Affinity Capture-MS Homo sapiens
76 KIRREL 55243
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 EXT1 2131
Affinity Capture-MS Homo sapiens
78 ALG8  
Affinity Capture-MS Homo sapiens
79 CDC45  
Affinity Capture-MS Homo sapiens
80 DSE 29940
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 SGTA 6449
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
82 PARL  
Affinity Capture-MS Homo sapiens
83 KIDINS220 57498
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 ALG2 85365
Affinity Capture-MS Homo sapiens
85 INTS5 80789
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 SLC25A30 253512
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 ADCY3 109
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 MANEA 79694
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 SLC25A16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 COLEC12 81035
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 SLC25A6 293
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 CD19 930
Affinity Capture-Western Homo sapiens
93 VPS52 6293
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 PIGA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 DSTYK 25778
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 ATL2 64225
Affinity Capture-MS Homo sapiens
97 XPR1 9213
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 RPTOR 57521
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 TUBB3 10381
Affinity Capture-MS Homo sapiens
101 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
102 UBE3C 9690
Affinity Capture-MS Homo sapiens
103 TMUB2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 TBRG4 9238
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 FAM69A 388650
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 C19orf52  
Affinity Capture-MS Homo sapiens
107 ATP2B2 491
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 TMED7 51014
Affinity Capture-MS Homo sapiens
109 ABHD17B 51104
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 ENTPD4 9583
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
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