Experiment description of studies that identified TARBP1 in exosomes

1 Experiment ID 234 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-C3 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 236 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

3 Experiment ID 254 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|FLOT1|CD81 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25950383     Organism Homo sapiens Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L" Journal name Pigment Cell Melanoma Res Publication year 2015 Sample Melanoma cells Sample name MNT-1 Isolation/purification methods Differential centrifugation Unltracentrifugation Sucrose density gradient Flotation density 1.13 - 1.19 g/mL Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

4 Experiment ID 258 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|FLOT1|CD81 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25950383     Organism Homo sapiens Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L" Journal name Pigment Cell Melanoma Res Publication year 2015 Sample Melanoma cells Sample name SKMEL28 Isolation/purification methods Differential centrifugation Unltracentrifugation Sucrose density gradient Flotation density 1.13 - 1.19 g/mL Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

5 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

6 Experiment ID 217 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|CD81|CD9|CD63 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23844026     Organism Homo sapiens Experiment description Characterization of human thymic exosomes. Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O." Journal name PLoS One Publication year 2013 Sample Thymus Sample name Normal-Thymus Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for TARBP1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 SLC2A12 154091 Affinity Capture-MS Homo sapiens 2 GYPA   Affinity Capture-MS Homo sapiens 3 HNRNPD 3184 Affinity Capture-MS Homo sapiens 4 SLA2 84174 Affinity Capture-MS Homo sapiens 5 LYPD3 27076 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 7 FASN 2194 Co-fractionation Homo sapiens 8 OCIAD1 54940 Affinity Capture-MS Homo sapiens 9 GMNN   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 10 EFNA4   Affinity Capture-MS Homo sapiens 11 FAF2 23197 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 SREK1 140890 Two-hybrid Homo sapiens 13 C19orf45   Affinity Capture-MS Homo sapiens 14 GPR17 2840 Affinity Capture-MS Homo sapiens 15 HSF4   Affinity Capture-Luminescence Homo sapiens Affinity Capture-MS Homo sapiens 16 KIF14 9928 Affinity Capture-MS Homo sapiens 17 IFT20 90410 Affinity Capture-MS Homo sapiens 18 DLG3 1741 Affinity Capture-MS Homo sapiens 19 OPALIN   Affinity Capture-MS Homo sapiens 20 CD79B 974 Affinity Capture-MS Homo sapiens 21 HCST   Affinity Capture-MS Homo sapiens 22 BSG 682 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 OSTM1 28962 Affinity Capture-MS Homo sapiens 24 NPTN 27020 Affinity Capture-MS Homo sapiens 25 VSIG1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 RP2 6102 Affinity Capture-MS Homo sapiens 27 CMKLR1 1240 Affinity Capture-MS Homo sapiens 28 CUL3 8452 Affinity Capture-MS Homo sapiens 29 NR3C1 2908 Proximity Label-MS Homo sapiens 30 Paxip1   Affinity Capture-MS Mus musculus 31 CTDP1 9150 Affinity Capture-MS Homo sapiens 32 PNMAL1   Affinity Capture-MS Homo sapiens 33 LOC102724334 102724334 Cross-Linking-MS (XL-MS) Homo sapiens 34 HIST1H3A 8350 Cross-Linking-MS (XL-MS) Homo sapiens 35 RAB6B 51560 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 36 TARS 6897 Co-fractionation Homo sapiens 37 SASS6 163786 Proximity Label-MS Homo sapiens 38 NEFH 4744 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 BAG6 7917 Affinity Capture-MS Homo sapiens 40 TNFRSF17   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 41 ASNA1 439 Co-fractionation Homo sapiens 42 ATXN7L1 222255 Affinity Capture-MS Homo sapiens 43 FAM19A3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 44 ABLIM3 22885 Affinity Capture-MS Homo sapiens 45 DLK2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 46 WDR48 57599 Affinity Capture-MS Homo sapiens 47 CHMP4B 128866 Affinity Capture-MS Homo sapiens 48 PBXIP1 57326 Affinity Capture-MS Homo sapiens 49 H2AFZ 3015 Cross-Linking-MS (XL-MS) Homo sapiens 50 CYB5B 80777 Affinity Capture-MS Homo sapiens 51 SCGB2A2   Affinity Capture-MS Homo sapiens 52 GPR182   Affinity Capture-MS Homo sapiens 53 CIT 11113 Affinity Capture-MS Homo sapiens 54 SYNCRIP 10492 Affinity Capture-MS Homo sapiens 55 H2AFV 94239 Cross-Linking-MS (XL-MS) Homo sapiens 56 SCN2B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 57 C3orf18   Affinity Capture-MS Homo sapiens 58 CREB3L3   Affinity Capture-MS Homo sapiens 59 RASL10B   Affinity Capture-MS Homo sapiens 60 CXCR4 7852 Affinity Capture-MS Homo sapiens 61 SCN3B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 62 CSPG5 10675 Affinity Capture-MS Homo sapiens 63 AKAP1 8165 Proximity Label-MS Homo sapiens 64 RGS20 8601 Affinity Capture-MS Homo sapiens 65 HYPM   Affinity Capture-MS Homo sapiens 66 FIS1 51024 Affinity Capture-MS Homo sapiens 67 ITFG3 83986 Affinity Capture-MS Homo sapiens 68 PLA2G10   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 69 Zbtb2 381990 Affinity Capture-MS Mus musculus View the network

Pathways in which TARBP1 is involved

No pathways found