Gene description for ATXN7L1
Gene name ataxin 7-like 1
Gene symbol ATXN7L1
Other names/aliases ATXN7L4
Species Homo sapiens
 Database cross references - ATXN7L1
ExoCarta ExoCarta_222255
Vesiclepedia VP_222255
Entrez Gene 222255
HGNC 22210
UniProt Q9ULK2  
 ATXN7L1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for ATXN7L1
Molecular Function
    protein binding GO:0005515 IPI
 Experiment description of studies that identified ATXN7L1 in exosomes
1
Experiment ID 237
MISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Enriched markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for ATXN7L1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ATXN7L1 is involved
No pathways found





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