Gene description for NIPBL
Gene name	Nipped-B homolog (Drosophila)
Gene symbol	NIPBL
Other names/aliases	CDLS CDLS1 IDN3 IDN3-B Scc2
Species	Homo sapiens
Database cross references - NIPBL
ExoCarta	ExoCarta_25836
Entrez Gene	25836
HGNC	28862
MIM	608667
UniProt	Q6KC79
NIPBL identified in exosomes derived from the following tissue/cell type
Plasma	19028452
Urine	19056867

Gene ontology annotations for NIPBL

Molecular Function     protein binding GO:0005515 IPI     protein N-terminus binding GO:0047485 IPI     chromatin binding GO:0003682 IEA     protein C-terminus binding GO:0008022 IPI     chromo shadow domain binding GO:0070087 IPI     mediator complex binding GO:0036033 IEA     histone deacetylase binding GO:0042826 IPI Biological Process     uterus morphogenesis GO:0061038 IMP     outflow tract morphogenesis GO:0003151 IMP     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IDA     cognition GO:0050890 IMP     metanephros development GO:0001656 NAS     embryonic digestive tract morphogenesis GO:0048557 IMP     cellular protein localization GO:0034613 IMP     fat cell differentiation GO:0045444 IEA     cellular response to X-ray GO:0071481 IMP     embryonic forelimb morphogenesis GO:0035115 IMP     eye morphogenesis GO:0048592 IMP     mitotic sister chromatid cohesion GO:0007064 IMP     sensory perception of sound GO:0007605 IMP     regulation of hair cycle GO:0042634 IMP     brain development GO:0007420 IMP     positive regulation of ossification GO:0045778 IEA     forelimb morphogenesis GO:0035136 IMP     negative regulation of transcription, DNA-templated GO:0045892 IDA     external genitalia morphogenesis GO:0035261 IMP     maintenance of mitotic sister chromatid cohesion GO:0034088 IMP     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IEA     embryonic viscerocranium morphogenesis GO:0048703 IEA     positive regulation of multicellular organism growth GO:0040018 IEA     cellular response to DNA damage stimulus GO:0006974 IMP     mitotic cell cycle GO:0000278 TAS     stem cell maintenance GO:0019827 IEA     face morphogenesis GO:0060325 IMP     positive regulation of histone deacetylation GO:0031065 IDA     ear morphogenesis GO:0042471 IMP     developmental growth GO:0048589 IMP     gall bladder development GO:0061010 IMP     regulation of developmental growth GO:0048638 IMP     heart morphogenesis GO:0003007 IMP     regulation of embryonic development GO:0045995 IMP Subcellular Localization     SMC loading complex GO:0032116 IDA     extracellular exosome GO:0070062 IDA     chromatin GO:0000785 IEA     nucleoplasm GO:0005654 TAS     nucleus GO:0005634 IDA