Gene description for MAPK9
Gene name	mitogen-activated protein kinase 9
Gene symbol	MAPK9
Other names/aliases	JNK-55 JNK2 JNK2A JNK2ALPHA JNK2B JNK2BETA PRKM9 SAPK SAPK1a p54a p54aSAPK
Species	Homo sapiens
Database cross references - MAPK9
ExoCarta	ExoCarta_5601
Entrez Gene	5601
HGNC	6886
MIM	602896
UniProt	P45984
MAPK9 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for MAPK9

Molecular Function     cysteine-type endopeptidase activator activity involved in apoptotic process GO:0008656 IEA     transcription factor binding GO:0008134 IDA     ATP binding GO:0005524 IEA     mitogen-activated protein kinase kinase kinase binding GO:0031435 IEA     protein binding GO:0005515 IPI     JUN kinase activity GO:0004705 IDA Biological Process     JNK cascade GO:0007254 TAS     rhythmic process GO:0048511 IEA     protein targeting to mitochondrion GO:0006626 IEA     TRIF-dependent toll-like receptor signaling pathway GO:0035666 TAS     Fc-epsilon receptor signaling pathway GO:0038095 TAS     positive regulation of cell morphogenesis involved in differentiation GO:0010770 IEA     regulation of JNK cascade GO:0046328 IEA     positive regulation of chemokine production GO:0032722 IEA     toll-like receptor 2 signaling pathway GO:0034134 TAS     positive regulation of nitric oxide biosynthetic process GO:0045429 IEA     cellular response to tumor necrosis factor GO:0071356 IEA     response to drug GO:0042493 IEA     MyD88-independent toll-like receptor signaling pathway GO:0002756 TAS     toll-like receptor 5 signaling pathway GO:0034146 TAS     cellular response to lipopolysaccharide GO:0071222 IEA     regulation of protein ubiquitination GO:0031396 IEA     neuron projection development GO:0031175 IEA     response to mechanical stimulus GO:0009612 IEA     positive regulation of prostaglandin biosynthetic process GO:0031394 IEA     MyD88-dependent toll-like receptor signaling pathway GO:0002755 TAS     toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 TAS     positive regulation of prostaglandin secretion GO:0032308 IEA     response to stress GO:0006950 TAS     activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 IEA     positive regulation of macrophage derived foam cell differentiation GO:0010744 IMP     cellular response to UV GO:0034644 IEA     innate immune response GO:0045087 TAS     regulation of circadian rhythm GO:0042752 ISS     release of cytochrome c from mitochondria GO:0001836 IEA     central nervous system development GO:0007417 IEA     toll-like receptor signaling pathway GO:0002224 TAS     toll-like receptor 3 signaling pathway GO:0034138 TAS     cellular response to growth factor stimulus GO:0071363 IEA     toll-like receptor 9 signaling pathway GO:0034162 TAS     JUN phosphorylation GO:0007258 IEA     regulation of sequence-specific DNA binding transcription factor activity GO:0051090 TAS     toll-like receptor 4 signaling pathway GO:0034142 TAS     positive regulation of apoptotic signaling pathway GO:2001235 IEA     protein phosphorylation GO:0006468 IMP     toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 TAS     positive regulation of gene expression GO:0010628 IMP     cellular response to interleukin-1 GO:0071347 IEA     stress-activated MAPK cascade GO:0051403 TAS     positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 IEA     response to amine GO:0014075 IEA     positive regulation of protein phosphorylation GO:0001934 IEA     response to cadmium ion GO:0046686 IEA     response to toxic substance GO:0009636 IEA     positive regulation of transcription, DNA-templated GO:0045893 IEA     toll-like receptor 10 signaling pathway GO:0034166 TAS Subcellular Localization     nucleoplasm GO:0005654 TAS     cytosol GO:0005829 TAS     mitochondrion GO:0005739 IEA