Experiment description of studies that identified JUND in exosomes

1 Experiment ID 226 ISEV standards ✔ EM EV Biophysical techniques ✔ GAPDH EV Cytosolic markers ✔ CD9|FLOT1 EV Membrane markers ✔ LMNA|H2AFX|ATP5A1|TOMM20 EV Negative markers ✘ EV Particle analysis Identified molecule mRNA Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa) PubMed ID 26027894     Organism Homo sapiens Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar Journal name Journal of Extracellular Vesicles Publication year 2015 Sample Endothelial cells Sample name HMEC-1 Isolation/purification methods Differential ultracentrifugation Sucrose density gradient Flotation density 1.10 g/mL Molecules identified in the study miRNA Protein snoRNA lncRNA yRNA snRNA mRNA ncRNA mtRNA vtRNA scaRNA lincRNA Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa) Western blotting

2 Experiment ID 237 ISEV standards ✔ EM EV Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH EV Cytosolic markers ✘ EV Membrane markers ✔ HSP90B1 EV Negative markers ✔ qNano EV Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for JUND

Protein Interactor ExoCarta ID Identification method PubMed Species 1 FOS 2353 Invitro Homo sapiens 2 NFE2L2 4780 Invivo Homo sapiens 3 BCL6   Invivo Homo sapiens Invitro Homo sapiens 4 MEN1 4221 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 5 COPS5 10987 Co-localization Homo sapiens 6 BRCA1 672 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 7 DDIT3 1649 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 8 MAPK8 5599 Reconstituted Complex Homo sapiens 9 BATF   Invitro Homo sapiens Two-hybrid Homo sapiens 10 SMAD4   Invitro Homo sapiens 11 ATF3   Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 12 MAPK9 5601 Invitro Homo sapiens 13 NFE2L1   Invivo Homo sapiens Invitro Homo sapiens 14 RFWD2   Affinity Capture-Western Homo sapiens 15 FOSL2   Invitro Homo sapiens View the network

Pathways in which JUND is involved

No pathways found