Gene description for MAP3K1
Gene name	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
Gene symbol	MAP3K1
Other names/aliases	MAPKKK1 MEKK MEKK 1 MEKK1 SRXY6
Species	Homo sapiens
Database cross references - MAP3K1
ExoCarta	ExoCarta_4214
Vesiclepedia	VP_4214
Entrez Gene	4214
HGNC	6848
MIM	600982
UniProt	Q13233
MAP3K1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for MAP3K1

Molecular Function     protein kinase activity GO:0004672 IDA     protein serine/threonine kinase activity GO:0004674 EXP     protein serine/threonine kinase activity GO:0004674 IBA     JUN kinase kinase kinase activity GO:0004706 IEA     MAP kinase kinase kinase activity GO:0004709 NAS     MAP kinase kinase kinase activity GO:0004709 TAS     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     zinc ion binding GO:0008270 IEA     protein kinase binding GO:0019901 IPI     protein serine kinase activity GO:0106310 IEA Biological Process     MAPK cascade GO:0000165 IEA     protein phosphorylation GO:0006468 NAS     Fc-epsilon receptor signaling pathway GO:0038095 TAS     cellular response to mechanical stimulus GO:0071260 IEP Subcellular Localization     cytoplasm GO:0005737 IBA     cytosol GO:0005829 TAS     tight junction GO:0070160 IDA