Gene description for ARHGAP4
Gene name	Rho GTPase activating protein 4
Gene symbol	ARHGAP4
Other names/aliases	C1 RGC1 RhoGAP4 SrGAP4 p115
Species	Homo sapiens
Database cross references - ARHGAP4
ExoCarta	ExoCarta_393
Entrez Gene	393
HGNC	674
MIM	300023
UniProt	P98171
ARHGAP4 identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for ARHGAP4

Molecular Function     GTPase activator activity GO:0005096 IEA     protein binding GO:0005515 IPI     Rac GTPase binding GO:0048365 IBA     SH3/SH2 adaptor activity GO:0005070 TAS Biological Process     small GTPase mediated signal transduction GO:0007264 TAS     negative regulation of cell migration GO:0030336 IBA     apoptotic signaling pathway GO:0097190 TAS     regulation of small GTPase mediated signal transduction GO:0051056 TAS     Rho protein signal transduction GO:0007266 TAS     cytoskeleton organization GO:0007010 TAS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     positive regulation of apoptotic process GO:0043065 TAS     positive regulation of signal transduction GO:0009967 TAS     negative regulation of axon extension GO:0030517 IEA     negative regulation of fibroblast migration GO:0010764 IEA     positive regulation of GTPase activity GO:0043547 TAS Subcellular Localization     cytoplasm GO:0005737 IDA     focal adhesion GO:0005925 IDA     nucleoplasm GO:0005654 IDA     growth cone GO:0030426 IEA     Golgi apparatus GO:0005794 IEA     microtubule GO:0005874 IEA     cytosol GO:0005829 TAS