Gene description for FGFR2
Gene name	fibroblast growth factor receptor 2
Gene symbol	FGFR2
Other names/aliases	BBDS BEK BFR-1 CD332 CEK3 CFD1 ECT1 JWS K-SAM KGFR TK14 TK25
Species	Homo sapiens
Database cross references - FGFR2
ExoCarta	ExoCarta_2263
Vesiclepedia	VP_2263
Entrez Gene	2263
HGNC	3689
MIM	176943
UniProt	P21802
FGFR2 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for FGFR2

Molecular Function     fibroblast growth factor binding GO:0017134 IPI     protein tyrosine kinase activity GO:0004713 NAS     heparin binding GO:0008201 IEA     ATP binding GO:0005524 IEA     fibroblast growth factor-activated receptor activity GO:0005007 NAS     protein binding GO:0005515 IPI     protein homodimerization activity GO:0042803 IPI Biological Process     lung development GO:0030324 ISS     regulation of branching involved in prostate gland morphogenesis GO:0060687 ISS     positive regulation of phospholipase activity GO:0010518 IMP     organ morphogenesis GO:0009887 ISS     positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 ISS     angiogenesis GO:0001525 ISS     epidermis morphogenesis GO:0048730 ISS     multicellular organism growth GO:0035264 ISS     epithelial cell differentiation GO:0030855 ISS     positive regulation of cell cycle GO:0045787 ISS     lateral sprouting from an epithelium GO:0060601 ISS     prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis GO:0060527 ISS     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISS     fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow GO:0035602 ISS     protein autophosphorylation GO:0046777 IDA     fibroblast growth factor receptor signaling pathway involved in hemopoiesis GO:0035603 ISS     Fc-epsilon receptor signaling pathway GO:0038095 TAS     innate immune response GO:0045087 TAS     positive regulation of smooth muscle cell proliferation GO:0048661 IEA     bone mineralization GO:0030282 ISS     fibroblast growth factor receptor signaling pathway GO:0008543 TAS     ventricular cardiac muscle tissue morphogenesis GO:0055010 ISS     negative regulation of mitotic nuclear division GO:0045839 IEA     regulation of ERK1 and ERK2 cascade GO:0070372 ISS     epidermal growth factor receptor signaling pathway GO:0007173 TAS     pyramidal neuron development GO:0021860 ISS     lacrimal gland development GO:0032808 ISS     mesenchymal cell proliferation involved in lung development GO:0060916 ISS     bud elongation involved in lung branching GO:0060449 ISS     neuromuscular junction development GO:0007528 IEA     coronal suture morphogenesis GO:0060365 IEA     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 ISS     embryonic cranial skeleton morphogenesis GO:0048701 IMP     squamous basal epithelial stem cell differentiation involved in prostate gland acinus development GO:0060529 ISS     positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISS     embryonic pattern specification GO:0009880 ISS     branching involved in labyrinthine layer morphogenesis GO:0060670 ISS     epithelial to mesenchymal transition GO:0001837 IEA     odontogenesis GO:0042476 ISS     branching morphogenesis of a nerve GO:0048755 ISS     mesenchymal cell differentiation involved in lung development GO:0060915 ISS     epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 ISS     lens fiber cell development GO:0070307 IEA     embryonic digestive tract morphogenesis GO:0048557 ISS     inner ear morphogenesis GO:0042472 ISS     branching involved in prostate gland morphogenesis GO:0060442 ISS     reproductive structure development GO:0048608 ISS     outflow tract septum morphogenesis GO:0003148 ISS     cell fate commitment GO:0045165 ISS     prostate epithelial cord elongation GO:0060523 ISS     regulation of fibroblast growth factor receptor signaling pathway GO:0040036 ISS     in utero embryonic development GO:0001701 ISS     post-embryonic development GO:0009791 ISS     positive regulation of cardiac muscle cell proliferation GO:0060045 ISS     regulation of osteoblast differentiation GO:0045667 TAS     digestive tract development GO:0048565 ISS     mesenchymal cell differentiation GO:0048762 ISS     positive regulation of Wnt signaling pathway GO:0030177 ISS     regulation of osteoblast proliferation GO:0033688 TAS     synaptic vesicle transport GO:0048489 IEA     positive regulation of mesenchymal cell proliferation GO:0002053 ISS     positive regulation of canonical Wnt signaling pathway GO:0090263 ISS     positive regulation of cell division GO:0051781 ISS     organ growth GO:0035265 ISS     regulation of multicellular organism growth GO:0040014 ISS     orbitofrontal cortex development GO:0021769 ISS     ureteric bud development GO:0001657 ISS     regulation of smooth muscle cell differentiation GO:0051150 ISS     phosphatidylinositol-mediated signaling GO:0048015 TAS     membranous septum morphogenesis GO:0003149 ISS     regulation of smoothened signaling pathway GO:0008589 ISS     branch elongation involved in salivary gland morphogenesis GO:0060667 ISS     negative regulation of transcription from RNA polymerase II promoter GO:0000122 ISS     fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development GO:0035607 ISS     mesodermal cell differentiation GO:0048333 IEA     lung-associated mesenchyme development GO:0060484 ISS     mammary gland bud formation GO:0060615 ISS     branching involved in salivary gland morphogenesis GO:0060445 ISS     embryonic organ morphogenesis GO:0048562 ISS     gland morphogenesis GO:0022612 ISS     otic vesicle formation GO:0030916 ISS     positive regulation of MAPK cascade GO:0043410 IMP     hair follicle morphogenesis GO:0031069 ISS     positive regulation of epithelial cell proliferation GO:0050679 ISS     regulation of morphogenesis of a branching structure GO:0060688 ISS     morphogenesis of embryonic epithelium GO:0016331 ISS     prostate gland morphogenesis GO:0060512 ISS     embryonic organ development GO:0048568 ISS     cell-cell signaling GO:0007267 ISS     positive regulation of cell proliferation GO:0008284 IMP     bone development GO:0060348 ISS     skeletal system morphogenesis GO:0048705 TAS     lung lobe morphogenesis GO:0060463 ISS     fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow GO:0035604 ISS     negative regulation of epithelial cell proliferation GO:0050680 IEA     insulin receptor signaling pathway GO:0008286 TAS     limb bud formation GO:0060174 ISS     bone morphogenesis GO:0060349 ISS     midbrain development GO:0030901 ISS     peptidyl-tyrosine phosphorylation GO:0018108 IDA     ventricular zone neuroblast division GO:0021847 ISS     apoptotic process GO:0006915 IEA     regulation of cell fate commitment GO:0010453 ISS     lung alveolus development GO:0048286 ISS     axonogenesis GO:0007409 ISS     endodermal digestive tract morphogenesis GO:0061031 IEA Subcellular Localization     extracellular matrix GO:0031012 IDA     integral component of membrane GO:0016021 NAS     extracellular region GO:0005576 IEA     nucleoplasm GO:0005654 IDA     cell surface GO:0009986 IDA     nucleus GO:0005634 IDA     cytoplasmic membrane-bounded vesicle GO:0016023 IEA     integral component of plasma membrane GO:0005887 IDA     membrane GO:0016020 NAS     cytoplasm GO:0005737 IDA     cell cortex GO:0005938 IDA     plasma membrane GO:0005886 TAS     excitatory synapse GO:0060076 ISS     Golgi apparatus GO:0005794 IEA     intracellular membrane-bounded organelle GO:0043231 IDA