Experiment description of studies that identified XPR1 in exosomes

1 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

2 Experiment ID 211 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|EpCAM|TFRC Enriched markers ✔ cytochrome c|GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name IGROV1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 212 MISEV standards ✔ CEM Biophysical techniques ✔ TSG101|Alix|EpCAM|TFRC Enriched markers ✔ Cytochrome C|GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23333927     Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K." Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name OVCAR-3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.09-1.15 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

4 Experiment ID 191 MISEV standards ✘ Biophysical techniques ✔ Alix|CD81|CD9 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 20124223     Organism Homo sapiens Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK." Journal name Mol Cell Proteomics Publication year 2010 Sample Squamous carcinoma cells Sample name Squamous carcinoma cell (A431) Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for XPR1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 TGOLN2 10618 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 GJD3   Proximity Label-MS Homo sapiens 3 Tmed2 56334 Affinity Capture-MS Mus musculus 4 UTRN 7402 Affinity Capture-MS Homo sapiens 5 OCLN 100506658 Proximity Label-MS Homo sapiens 6 VAPA 9218 Affinity Capture-MS Homo sapiens 7 LAMP3   Proximity Label-MS Homo sapiens 8 PDCD1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 DBN1 1627 Affinity Capture-MS Homo sapiens 10 LAMP2 3920 Proximity Label-MS Homo sapiens 11 Actb 11461 Affinity Capture-MS Mus musculus 12 STX4 6810 Proximity Label-MS Homo sapiens 13 MLLT4 4301 Proximity Label-MS Homo sapiens 14 CTLA4   Affinity Capture-MS Homo sapiens 15 KIF5B 3799 Affinity Capture-MS Homo sapiens 16 SNX27 81609 Affinity Capture-MS Homo sapiens 17 GAK 2580 Affinity Capture-MS Homo sapiens 18 C3orf52   Affinity Capture-MS Homo sapiens 19 STX6 10228 Proximity Label-MS Homo sapiens 20 DGCR2 9993 Affinity Capture-MS Homo sapiens 21 RAB35 11021 Proximity Label-MS Homo sapiens 22 KIAA1161 57462 Affinity Capture-MS Homo sapiens 23 FAF2 23197 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 EBAG9 9166 Proximity Label-MS Homo sapiens 25 AMOT   Proximity Label-MS Homo sapiens 26 NUP155 9631 Proximity Label-MS Homo sapiens 27 VSIG1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 28 C19orf38   Affinity Capture-MS Homo sapiens 29 CEACAM21   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 30 LYN 4067 Proximity Label-MS Homo sapiens 31 Sec24c   Affinity Capture-MS Mus musculus 32 MCAM 4162 Proximity Label-MS Homo sapiens 33 VSIG4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 34 DNAJC5 80331 Proximity Label-MS Homo sapiens 35 PBXIP1 57326 Affinity Capture-MS Homo sapiens 36 DIRAS3   Proximity Label-MS Homo sapiens 37 BACE2 25825 Affinity Capture-MS Homo sapiens 38 GPR182   Affinity Capture-MS Homo sapiens 39 Coro1c 23790 Affinity Capture-MS Mus musculus 40 UPK1A 11045 Affinity Capture-MS Homo sapiens 41 VSTM1   Affinity Capture-MS Homo sapiens 42 RHOT2 89941 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 43 Chmp4b 75608 Affinity Capture-MS Mus musculus 44 PTGIR   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 45 Rab5c 19345 Affinity Capture-MS Mus musculus 46 NTRK1 4914 Affinity Capture-MS Homo sapiens 47 SLC15A1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 48 EFNA4   Affinity Capture-MS Homo sapiens 49 APLNR   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 50 TTYH1   Affinity Capture-MS Homo sapiens 51 CD79B 974 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 52 EPB41L4A 64097 Proximity Label-MS Homo sapiens 53 LAMP1 3916 Proximity Label-MS Homo sapiens 54 PTH2R   Affinity Capture-MS Homo sapiens 55 Bmpr1a   Affinity Capture-MS Mus musculus 56 CMKLR1 1240 Affinity Capture-MS Homo sapiens 57 GOLT1B 51026 Affinity Capture-MS Homo sapiens 58 Rmdn3   Affinity Capture-MS Mus musculus 59 TNFRSF1A 7132 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 60 EGFR 1956 Negative Genetic Homo sapiens 61 TMEM74   Affinity Capture-MS Homo sapiens 62 CD226 10666 Affinity Capture-MS Homo sapiens 63 Kif5b 16573 Affinity Capture-MS Mus musculus 64 FGFR2 2263 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 65 SLC3A2 6520 Affinity Capture-MS Homo sapiens 66 RHOB 388 Proximity Label-MS Homo sapiens 67 CLTC 1213 Affinity Capture-MS Homo sapiens 68 KIDINS220 57498 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 69 FLOT1 10211 Proximity Label-MS Homo sapiens 70 TACC3   Affinity Capture-MS Homo sapiens 71 SLC4A2 6522 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 72 MAGEA8   Affinity Capture-MS Homo sapiens 73 TMEM9 252839 Affinity Capture-MS Homo sapiens 74 KCNA2   Affinity Capture-MS Homo sapiens 75 RNF19B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 76 OR10H2   Affinity Capture-MS Homo sapiens 77 RYK 6259 Affinity Capture-MS Homo sapiens 78 LCK 3932 Proximity Label-MS Homo sapiens 79 B4GAT1 11041 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 80 ELAVL1 1994 Affinity Capture-RNA Homo sapiens 81 C11orf52 91894 Proximity Label-MS Homo sapiens 82 DNAJC5B   Proximity Label-MS Homo sapiens 83 RAB7A 7879 Affinity Capture-MS Homo sapiens 84 Flot1 14251 Affinity Capture-MS Mus musculus 85 EPHA2 1969 Proximity Label-MS Homo sapiens 86 NLGN3   Affinity Capture-MS Homo sapiens 87 DNAJC1 64215 Proximity Label-MS Homo sapiens 88 KRAS 3845 Proximity Label-MS Homo sapiens Negative Genetic Homo sapiens 89 RAB5C 5878 Affinity Capture-MS Homo sapiens 90 Ptpn23 104831 Affinity Capture-MS Mus musculus 91 DKKL1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens View the network

Pathways in which XPR1 is involved

No pathways found