Gene description for Tmed2
Gene name	transmembrane emp24 domain trafficking protein 2
Gene symbol	Tmed2
Other names/aliases	1110032D12Rik 1810020N21Rik Rnp24 Sid394 p24beta1
Species	Mus musculus
Database cross references - Tmed2
ExoCarta	ExoCarta_56334
Vesiclepedia	VP_56334
Entrez Gene	56334
UniProt	Q9R0Q3
Tmed2 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Tmed2

Molecular Function     frizzled binding GO:0005109 IPI     smoothened binding GO:0005119 IPI     protein binding GO:0005515 IPI Biological Process     in utero embryonic development GO:0001701 IMP     somitogenesis GO:0001756 IMP     neural tube closure GO:0001843 IMP     embryonic placenta development GO:0001892 IMP     maternal placenta development GO:0001893 IMP     heart looping GO:0001947 IMP     intracellular protein transport GO:0006886 IBA     intracellular protein transport GO:0006886 IEA     intracellular protein transport GO:0006886 ISO     endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 IBA     inflammatory response GO:0006954 IMP     endoplasmic reticulum organization GO:0007029 IMP     Golgi organization GO:0007030 IBA     Golgi organization GO:0007030 ISO     Golgi organization GO:0007030 ISS     protein localization GO:0008104 IMP     protein secretion GO:0009306 IMP     positive regulation of gene expression GO:0010628 IMP     vesicle-mediated transport GO:0016192 IEA     somite rostral/caudal axis specification GO:0032525 IMP     negative regulation of GTPase activity GO:0034260 ISO     negative regulation of GTPase activity GO:0034260 ISS     multicellular organism growth GO:0035264 IMP     post-anal tail morphogenesis GO:0036342 IMP     PERK-mediated unfolded protein response GO:0036499 IMP     negative regulation of smoothened signaling pathway GO:0045879 IMP     embryonic morphogenesis GO:0048598 IMP     branching involved in labyrinthine layer morphogenesis GO:0060670 IMP     labyrinthine layer blood vessel development GO:0060716 IMP     chorion development GO:0060717 IMP     maintenance of protein localization in organelle GO:0072595 IMP     protein localization to plasma membrane GO:0072659 ISO     protein localization to plasma membrane GO:0072659 ISS     endoplasmic reticulum membrane organization GO:0090158 IMP     negative regulation of protein localization to plasma membrane GO:1903077 IMP     negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation GO:1903912 IMP     allantois development GO:1905069 IMP     regulation of SREBP signaling pathway GO:2000638 IMP Subcellular Localization     endoplasmic reticulum GO:0005783 IBA     endoplasmic reticulum GO:0005783 ISO     endoplasmic reticulum GO:0005783 ISS     endoplasmic reticulum membrane GO:0005789 IDA     endoplasmic reticulum-Golgi intermediate compartment GO:0005793 IBA     endoplasmic reticulum-Golgi intermediate compartment GO:0005793 IDA     endoplasmic reticulum-Golgi intermediate compartment GO:0005793 ISO     endoplasmic reticulum-Golgi intermediate compartment GO:0005793 ISS     Golgi apparatus GO:0005794 IBA     Golgi apparatus GO:0005794 IDA     Golgi apparatus GO:0005794 IDA     Golgi apparatus GO:0005794 ISO     Golgi apparatus GO:0005794 ISS     membrane GO:0016020 ISO     membrane GO:0016020 ISS     COPII-coated ER to Golgi transport vesicle GO:0030134 IBA     COPI-coated vesicle GO:0030137 ISO     COPI-coated vesicle GO:0030137 ISS     COPI-coated vesicle membrane GO:0030663 IEA     Golgi cisterna membrane GO:0032580 IEA     endoplasmic reticulum-Golgi intermediate compartment membrane GO:0033116 IEA     zymogen granule membrane GO:0042589 ISO     zymogen granule membrane GO:0042589 ISS     intracellular membrane-bounded organelle GO:0043231 ISO