Gene ontology annotations for INADL
Experiment description of studies that identified INADL in exosomes
1
Experiment ID
207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DKO-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
Dks-8
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
209
MISEV standards
✘
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DLD-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
4
Experiment ID
211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
5
Experiment ID
212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
6
Experiment ID
275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25844599
Organism
Homo sapiens
Experiment description
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors
"Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name
Oncotarget
Publication year
2015
Sample
Prostate cancer cells
Sample name
DU145 - Docetaxel sensitive
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.12-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry/Flow cytometry/Western blotting
7
Experiment ID
274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25844599
Organism
Homo sapiens
Experiment description
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors
"Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name
Oncotarget
Publication year
2015
Sample
Prostate cancer cells
Sample name
DU145 - Docetaxel resistant
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.18 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Flow cytometry Western blotting
8
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
9
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
10
Experiment ID
63
MISEV standards
✘
Biophysical techniques
✔
AQP2
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19056867
Organism
Homo sapiens
Experiment description
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors
"Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name
JASN
Publication year
2009
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
Protein-protein interactions for INADL
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
PARD3
56288
Proximity Label-MS
Homo sapiens
2
ARHGAP17
55114
Affinity Capture-MS
Homo sapiens
3
HOMER1
Two-hybrid
Homo sapiens
4
HOMER3
9454
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
5
SNCA
6622
Affinity Capture-MS
Homo sapiens
6
C2CD4B
Affinity Capture-MS
Homo sapiens
7
Tmed2
56334
Affinity Capture-MS
Mus musculus
8
Wwtr1
Affinity Capture-MS
Mus musculus
9
GJB2
Affinity Capture-MS
Homo sapiens
10
Lin7c
22343
Affinity Capture-MS
Mus musculus
11
NECAB2
Two-hybrid
Homo sapiens
12
AMOT
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Proximity Label-MS
Homo sapiens
Proximity Label-MS
Homo sapiens
13
CEP170P1
Affinity Capture-MS
Homo sapiens
14
OCLN
100506658
Proximity Label-MS
Homo sapiens
15
RNF166
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
16
ANLN
54443
Affinity Capture-MS
Homo sapiens
17
CINP
Two-hybrid
Homo sapiens
18
AMOTL2
51421
Affinity Capture-MS
Homo sapiens
19
EPB41L4A
64097
Proximity Label-MS
Homo sapiens
20
ANAPC15
Affinity Capture-MS
Homo sapiens
21
FAM124A
Affinity Capture-MS
Homo sapiens
22
RAB32
10981
Affinity Capture-MS
Homo sapiens
23
GBA
2629
Affinity Capture-MS
Homo sapiens
24
CAPZB
832
Co-fractionation
Homo sapiens
25
METTL21B
Affinity Capture-MS
Homo sapiens
26
PHYH
5264
Two-hybrid
Homo sapiens
27
MPP5
64398
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
28
WWC1
Affinity Capture-MS
Homo sapiens
29
GIPC2
54810
Two-hybrid
Homo sapiens
30
LATS1
Proximity Label-MS
Homo sapiens
Proximity Label-MS
Homo sapiens
31
PSMD14
10213
Affinity Capture-MS
Homo sapiens
32
HSF2
Affinity Capture-MS
Homo sapiens
33
LIN7A
8825
Affinity Capture-MS
Homo sapiens
34
TJP3
Reconstituted Complex
Homo sapiens
35
RNF146
Affinity Capture-Luminescence
Homo sapiens
Proximity Label-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
36
RNASEH2A
10535
Affinity Capture-MS
Homo sapiens
37
CDH1
999
Proximity Label-MS
Homo sapiens
38
MLLT4
4301
Proximity Label-MS
Homo sapiens
39
YAP1
10413
Affinity Capture-MS
Homo sapiens
Proximity Label-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
40
Tpx2
Affinity Capture-MS
Mus musculus
41
C16orf72
29035
Affinity Capture-MS
Homo sapiens
42
FLOT1
10211
Proximity Label-MS
Homo sapiens
43
SAV1
Proximity Label-MS
Homo sapiens
44
LIN7C
55327
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
45
Kif13b
Affinity Capture-MS
Mus musculus
46
CIT
11113
Affinity Capture-MS
Homo sapiens
47
DTX2
113878
Proximity Label-MS
Homo sapiens
48
TP53RK
112858
Affinity Capture-MS
Homo sapiens
49
PRC1
9055
Affinity Capture-MS
Homo sapiens
50
CEP57L1
Two-hybrid
Homo sapiens
51
Yap1
Affinity Capture-MS
Mus musculus
Affinity Capture-MS
Mus musculus
Reconstituted Complex
Mus musculus
52
RHOB
388
Proximity Label-MS
Homo sapiens
53
Nedd1
Affinity Capture-MS
Mus musculus
54
CLDN1
9076
Reconstituted Complex
Homo sapiens
55
Ufl1
Affinity Capture-MS
Mus musculus
56
LATS2
26524
Affinity Capture-MS
Homo sapiens
Proximity Label-MS
Homo sapiens
57
FHL2
2274
Affinity Capture-MS
Homo sapiens
58
LIN7B
Affinity Capture-MS
Homo sapiens
59
Plekhg5
Affinity Capture-MS
Mus musculus
60
SLC33A1
9197
Affinity Capture-MS
Homo sapiens
61
LURAP1
Affinity Capture-MS
Homo sapiens
62
PCDHAC2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
63
BAI1
Protein-peptide
Homo sapiens
View the network
image/svg+xml
Pathways in which INADL is involved
No pathways found