Gene description for GIPC2
Gene name GIPC PDZ domain containing family, member 2
Gene symbol GIPC2
Other names/aliases SEMCAP-2
SEMCAP2
Species Homo sapiens
 Database cross references - GIPC2
ExoCarta ExoCarta_54810
Entrez Gene 54810
HGNC 18177
UniProt Q8TF65  
 GIPC2 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for GIPC2
Molecular Function
    molecular_function GO:0003674 ND
    protein binding GO:0005515 IPI
Biological Process
    biological_process GO:0008150 ND
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified GIPC2 in exosomes
1
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for GIPC2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MGC15730  
Two-hybrid Homo sapiens
2 PTN  
Two-hybrid Homo sapiens
3 UNC119  
Two-hybrid Homo sapiens
4 SETDB1  
Two-hybrid Homo sapiens
5 FZD3  
Invivo Homo sapiens
View the network image/svg+xml
 Pathways in which GIPC2 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here