Gene description for GIPC2
Gene name
GIPC PDZ domain containing family, member 2
Gene symbol
GIPC2
Other names/aliases
SEMCAP-2 SEMCAP2
Species
Homo sapiens
Database cross references - GIPC2
ExoCarta
ExoCarta_54810
Vesiclepedia
VP_54810
Entrez Gene
54810
HGNC
18177
UniProt
Q8TF65
GIPC2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells
36408942
Urine
19056867
Gene ontology annotations for GIPC2
Experiment description of studies that identified GIPC2 in exosomes
1
Experiment ID
488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Homo sapiens
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Mesenchymal stem cells
Sample name
UCMSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
2
Experiment ID
63
MISEV standards
✘
Biophysical techniques
✔
AQP2
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19056867
Organism
Homo sapiens
Experiment description
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors
"Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name
JASN
Publication year
2009
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
Protein-protein interactions for GIPC2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
COL6A1
1291
Co-fractionation
Homo sapiens
2
INADL
10207
Two-hybrid
Homo sapiens
3
PTN
Two-hybrid
Homo sapiens
4
GIPC1
10755
Proximity Label-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
5
IRF4
Two-hybrid
Homo sapiens
6
APPL1
26060
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
7
SH3BP4
23677
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
8
CTRC
Two-hybrid
Homo sapiens
9
ZBTB26
Two-hybrid
Homo sapiens
10
HSP90AB1
3326
Cross-Linking-MS (XL-MS)
Homo sapiens
11
PLEKHA2
59339
Two-hybrid
Homo sapiens
12
ZCCHC7
Two-hybrid
Homo sapiens
13
SETDB1
Two-hybrid
Homo sapiens
14
GIPC2
54810
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
15
PSMD14
10213
Affinity Capture-MS
Homo sapiens
16
COL1A1
1277
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
17
LZTS2
84445
Two-hybrid
Homo sapiens
18
UBE2I
7329
Two-hybrid
Homo sapiens
19
IGSF21
Two-hybrid
Homo sapiens
20
UNC119
9094
Two-hybrid
Homo sapiens
21
ARHGEF12
23365
Proximity Label-MS
Homo sapiens
22
SEMA4C
54910
Affinity Capture-MS
Homo sapiens
23
SP100
6672
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which GIPC2 is involved
No pathways found