Gene description for GIPC2
Gene name GIPC PDZ domain containing family, member 2
Gene symbol GIPC2
Other names/aliases SEMCAP-2
SEMCAP2
Species Homo sapiens
 Database cross references - GIPC2
ExoCarta ExoCarta_54810
Vesiclepedia VP_54810
Entrez Gene 54810
HGNC 18177
UniProt Q8TF65  
 GIPC2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
Urine 19056867    
 Gene ontology annotations for GIPC2
Molecular Function
    molecular_function GO:0003674 ND
    protein binding GO:0005515 IPI
Biological Process
    biological_process GO:0008150 ND
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified GIPC2 in exosomes
1
Experiment ID 488
MISEV standards
EM
EV Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
CANX
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 63
MISEV standards
EV Biophysical techniques
AQP2
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for GIPC2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MGC15730  
Two-hybrid Homo sapiens
2 PTN  
Two-hybrid Homo sapiens
3 UNC119 9094
Two-hybrid Homo sapiens
4 SETDB1  
Two-hybrid Homo sapiens
5 FZD3  
Invivo Homo sapiens
View the network image/svg+xml
 Pathways in which GIPC2 is involved
No pathways found





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