Experiment description of studies that identified RNASEH2A in sEVs

1 Experiment ID 236 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 217 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|CD81|CD9|CD63 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23844026     Organism Homo sapiens Experiment description Characterization of human thymic exosomes. Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O." Journal name PLoS One Publication year 2013 Sample Thymus Sample name Normal-Thymus Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for RNASEH2A

Protein Interactor ExoCarta ID Identification method PubMed Species 1 UBE2H 7328 Affinity Capture-MS Homo sapiens 2 KLHL36   Affinity Capture-MS Homo sapiens 3 INADL 10207 Affinity Capture-MS Homo sapiens 4 KPTN   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 OSBP2   Affinity Capture-MS Homo sapiens 6 FBXW11   Affinity Capture-MS Homo sapiens 7 RAD51   Affinity Capture-MS Homo sapiens 8 RNASEH2B   Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 SMARCA2 6595 Affinity Capture-MS Homo sapiens 10 ITSN1 6453 Co-fractionation Homo sapiens 11 AGPAT1 10554 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 PSRC1   Affinity Capture-MS Homo sapiens 13 FAS 355 Proximity Label-MS Homo sapiens 14 ITLN1 55600 Affinity Capture-MS Homo sapiens 15 RIN3   Affinity Capture-MS Homo sapiens 16 DDX39B 7919 Affinity Capture-MS Homo sapiens 17 DNAJA2 10294 Affinity Capture-MS Homo sapiens 18 PRDX2 7001 Affinity Capture-MS Homo sapiens 19 PHF20L1   Affinity Capture-MS Homo sapiens 20 NUBP2 10101 Affinity Capture-MS Homo sapiens 21 AP1M1 8907 Co-fractionation Homo sapiens 22 CUL3 8452 Affinity Capture-MS Homo sapiens 23 IPO7 10527 Co-fractionation Homo sapiens 24 DMXL1 1657 Affinity Capture-MS Homo sapiens 25 RNASEH2C 84153 Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 NANS 54187 Affinity Capture-MS Homo sapiens 27 BPNT1 10380 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 28 COG2 22796 Affinity Capture-MS Homo sapiens 29 SHMT2 6472 Affinity Capture-RNA Homo sapiens 30 MAMDC2 256691 Affinity Capture-MS Homo sapiens 31 DUSP16   Affinity Capture-MS Homo sapiens 32 FEN1 2237 Affinity Capture-MS Homo sapiens 33 N6AMT1 29104 Affinity Capture-MS Homo sapiens 34 PCNA 5111 Affinity Capture-MS Homo sapiens 35 KLHL1   Affinity Capture-MS Homo sapiens 36 C6orf141   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 37 UGDH 7358 Co-fractionation Homo sapiens 38 C19orf47   Affinity Capture-MS Homo sapiens 39 TTF1   Affinity Capture-MS Homo sapiens 40 DECR2 26063 Affinity Capture-MS Homo sapiens 41 MOV10 4343 Affinity Capture-RNA Homo sapiens 42 NDOR1   Co-fractionation Homo sapiens 43 IARS2 55699 Affinity Capture-MS Homo sapiens 44 PAPSS1 9061 Affinity Capture-MS Homo sapiens 45 HSPA1A 3303 Affinity Capture-MS Homo sapiens 46 DNAJA1 3301 Affinity Capture-MS Homo sapiens 47 NOX5   Affinity Capture-MS Homo sapiens 48 LGMN 5641 Affinity Capture-MS Homo sapiens 49 EDF1 8721 Co-fractionation Homo sapiens 50 C9orf72   Affinity Capture-MS Homo sapiens 51 FYTTD1   Affinity Capture-MS Homo sapiens 52 INPP5B 3633 Affinity Capture-MS Homo sapiens 53 CDK10   Affinity Capture-MS Homo sapiens 54 SETD3 84193 Co-fractionation Homo sapiens 55 ICAM5 7087 Affinity Capture-MS Homo sapiens 56 DOCK6 57572 Affinity Capture-MS Homo sapiens 57 LAMA5 3911 Affinity Capture-MS Homo sapiens 58 NDUFA3   Affinity Capture-MS Homo sapiens 59 FAM136A 84908 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 60 POLDIP3 84271 Affinity Capture-MS Homo sapiens View the network

Pathways in which RNASEH2A is involved

No pathways found