Gene description for RNASEH2A |
Gene name |
ribonuclease H2, subunit A |
Gene symbol |
RNASEH2A |
Other names/aliases |
AGS4 JUNB RNASEHI RNHIA RNHL |
Species |
Homo sapiens |
Database cross references - RNASEH2A |
ExoCarta |
ExoCarta_10535 |
Vesiclepedia |
VP_10535 |
Entrez Gene |
10535 |
HGNC |
18518 |
MIM |
606034 |
UniProt |
O75792
|
RNASEH2A identified in exosomes derived from the following tissue/cell type |
Hepatocellular carcinoma cells
|
26054723
|
Thymus
|
23844026
|
Gene ontology annotations for RNASEH2A |
|
Experiment description of studies that identified RNASEH2A in exosomes |
1 |
Experiment ID |
236 |
MISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|Alix|HSC70|GAPDH
|
EV Enriched markers |
✔
HSP90B1
|
EV Negative markers |
✔
qNano
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
26054723
|
Organism |
Homo sapiens |
Experiment description |
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs |
Authors |
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N |
Journal name |
Carcinogenesis
|
Publication year |
2015 |
Sample |
Hepatocellular carcinoma cells |
Sample name |
MHCC97L |
Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient |
Flotation density |
1.13-1.19 g/mL
|
Molecules identified in the study |
Protein RNA |
Methods used in the study |
Western blotting Mass spectrometry RT-PCR RNA Sequencing |
|
|
2 |
Experiment ID |
217 |
MISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|CD81|CD9|CD63
|
EV Enriched markers |
✘
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23844026
|
Organism |
Homo sapiens |
Experiment description |
Characterization of human thymic exosomes. |
Authors |
Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. |
Journal name |
PLoS One
|
Publication year |
2013 |
Sample |
Thymus |
Sample name |
Normal-Thymus |
Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
Protein-protein interactions for RNASEH2A |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which RNASEH2A is involved |
No pathways found
|
|
|