Gene description for COG2
Gene name component of oligomeric golgi complex 2
Gene symbol COG2
Other names/aliases LDLC
Species Homo sapiens
 Database cross references - COG2
ExoCarta ExoCarta_22796
Entrez Gene 22796
HGNC 6546
MIM 606974
UniProt Q14746  
 COG2 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for COG2
Molecular Function
    protein transporter activity GO:0008565 IMP
    protein complex binding GO:0032403 IEA
    protein binding GO:0005515 IPI
Biological Process
    intra-Golgi vesicle-mediated transport GO:0006891 IMP
    Golgi organization GO:0007030 IMP
    protein glycosylation GO:0006486 TAS
    intracellular protein transport GO:0006886 TAS
    oligosaccharide biosynthetic process GO:0009312 TAS
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    Golgi transport complex GO:0017119 IMP
    cytosol GO:0005829 IEA
    Golgi stack GO:0005795 IDA
 Experiment description of studies that identified COG2 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COG2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 COG3 83548
Invivo Homo sapiens
Invivo Homo sapiens
Invitro Homo sapiens
Invitro Homo sapiens
2 COG4 25839
Invivo Homo sapiens
Invivo Homo sapiens
Invitro Homo sapiens
Invitro Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which COG2 is involved
No pathways found





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