Gene description for PIGR
Gene name polymeric immunoglobulin receptor
Gene symbol PIGR
Other names/aliases -
Species Homo sapiens
 Database cross references - PIGR
ExoCarta ExoCarta_5284
Vesiclepedia VP_5284
Entrez Gene 5284
HGNC 8968
MIM 173880
UniProt P01833  
 PIGR identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast milk 17641064    
Breast milk 17641064    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Liver cancer cells 25265333    
Mesenchymal stem cells Unpublished / Not applicable
Plasma 19028452    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Saliva 18520029    
Saliva 19199708    
Urine 15326289    
Urine 19056867    
Urine 21595033    
Urine 21595033    
Urine 21595033    
Urine 25452312    
 Gene ontology annotations for PIGR
Molecular Function
    polymeric immunoglobulin binding GO:0001790 IDA
    polymeric immunoglobulin receptor activity GO:0001792 IDA
    transmembrane signaling receptor activity GO:0004888 IBA
Biological Process
    detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 IDA
    immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor GO:0002415 IBA
    immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor GO:0002415 IDA
    signal transduction GO:0007165 IBA
    epidermal growth factor receptor signaling pathway GO:0007173 IDA
    Fc receptor signaling pathway GO:0038093 IDA
    receptor clustering GO:0043113 IDA
Subcellular Localization
    extracellular space GO:0005615 HDA
    extracellular space GO:0005615 IDA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    azurophil granule membrane GO:0035577 TAS
    receptor complex GO:0043235 IDA
    extracellular exosome GO:0070062 HDA
    secretory IgA immunoglobulin complex GO:0071751 IDA
 Experiment description of studies that identified PIGR in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 46
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
HSC70|CD63|MHCII|CD81|CD86
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17641064    
Organism Homo sapiens
Experiment description Exosomes with immune modulatory features are present in human breast milk.
Authors "Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S"
Journal name JIMMU
Publication year 2007
Sample Breast milk
Sample name Breast milk - Colostrum
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.10-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
FACS
6
Experiment ID 48
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
HSC70|CD63|CD86|MHCII
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17641064    
Organism Homo sapiens
Experiment description Exosomes with immune modulatory features are present in human breast milk.
Authors "Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S"
Journal name JIMMU
Publication year 2007
Sample Breast milk
Sample name Breast milk - Mature milk
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.10-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
FACS
7
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 267
MISEV standards
✘ Biophysical techniques
✔
TSG101|Alix
Enriched markers
✔
CANX|HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Authors "Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J"
Journal name J Proteome Res
Publication year 2014
Sample Liver cancer cells
Sample name Huh-7 - Transfected with HBx plasmids
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
12
Experiment ID 44
MISEV standards
✔
IEM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19028452    
Organism Homo sapiens
Experiment description Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein.
Authors "Looze C, Yui D, Leung L, Ingham M, Kaler M, Yao X, Wu WW, Shen RF, Daniels MP, Levine SJ"
Journal name BBRC
Publication year 2009
Sample Plasma
Sample name Plasma
Isolation/purification methods Filtration
Size exclusion
Sucrose density gradient
Flotation density 1.15-1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
13
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 64
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method N-terminal animo acid sequencing
PubMed ID 18520029    
Organism Homo sapiens
Experiment description Exosome-like vesicles with dipeptidyl peptidase IV in human saliva.
Authors "Ogawa Y, Kanai-Azuma M, Akimoto Y, Kawakami H, Yanoshita R"
Journal name BPB
Publication year 2008
Sample Saliva
Sample name Saliva
Isolation/purification methods Filtration
Diafiltration
Gel filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Immunoelectron Microscopy
N-terminal animo acid sequencing
17
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
18
Experiment ID 13
MISEV standards
✔
IEM
Biophysical techniques
✔
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors "Pisitkun T, Shen RF, Knepper MA"
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
19
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
20
Experiment ID 193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 194
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 195
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 238
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25452312    
Organism Homo sapiens
Experiment description N-linked (N-) glycoproteomics of urimary exosomes
Authors "Saraswat M, Joenvaara S, Musante L, Peltoniemi H4, Holthofer H, Renkonen R."
Journal name Mol Cell Proteomics
Publication year 2014
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Filtration
Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for PIGR
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
2 MIS12  
Affinity Capture-MS Homo sapiens
3 KMT2C 58508
Affinity Capture-MS Homo sapiens
4 KRT1 3848
Affinity Capture-MS Homo sapiens
5 FCN1 2219
Affinity Capture-MS Homo sapiens
6 CRYGN  
Affinity Capture-MS Homo sapiens
7 LGALS1 3956
Affinity Capture-MS Homo sapiens
8 MCCC1 56922
Affinity Capture-MS Homo sapiens
9 EBF2  
Affinity Capture-MS Homo sapiens
10 NOX4  
Affinity Capture-MS Homo sapiens
11 LOXL4 84171
Affinity Capture-MS Homo sapiens
12 SNRPF 6636
Affinity Capture-MS Homo sapiens
13 FNDC5  
Affinity Capture-MS Homo sapiens
14 POTEF 728378
Affinity Capture-MS Homo sapiens
15 USP36  
Affinity Capture-MS Homo sapiens
16 RAB3B 5865
Reconstituted Complex Homo sapiens
17 LAMA2 3908
Affinity Capture-MS Homo sapiens
18 B3GNT2 10678
Affinity Capture-MS Homo sapiens
19 PC 5091
Affinity Capture-MS Homo sapiens
20 SDHB 6390
Affinity Capture-MS Homo sapiens
21 GKN1  
Affinity Capture-MS Homo sapiens
22 SEC24C 9632
Affinity Capture-MS Homo sapiens
23 EGFL8  
Affinity Capture-MS Homo sapiens
24 HINT2 84681
Affinity Capture-MS Homo sapiens
25 SCRIB 23513
Affinity Capture-MS Homo sapiens
26 KCTD21 283219
Affinity Capture-MS Homo sapiens
27 KLF15  
Affinity Capture-MS Homo sapiens
28 SFXN4  
Affinity Capture-MS Homo sapiens
29 NXT1  
Affinity Capture-MS Homo sapiens
30 TATDN1 83940
Affinity Capture-MS Homo sapiens
31 ZNF202  
Affinity Capture-MS Homo sapiens
32 UGT3A2  
Affinity Capture-MS Homo sapiens
33 SNX27 81609
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 C10orf53  
Affinity Capture-MS Homo sapiens
35 ICE2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 NOTCH2 4853
Affinity Capture-MS Homo sapiens
37 LUM 4060
Affinity Capture-MS Homo sapiens
38 EPB41L3 23136
Affinity Capture-MS Homo sapiens
39 PMEPA1 56937
Affinity Capture-MS Homo sapiens
40 DDX31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 GNG8  
Affinity Capture-MS Homo sapiens
42 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
43 PCK2 5106
Affinity Capture-MS Homo sapiens
44 ZDHHC19  
Affinity Capture-MS Homo sapiens
45 SPNS3  
Affinity Capture-MS Homo sapiens
46 GOLGA8A 23015
Affinity Capture-MS Homo sapiens
47 TUFM 7284
Affinity Capture-MS Homo sapiens
48 CHAC2 494143
Affinity Capture-MS Homo sapiens
49 ACACA 31
Affinity Capture-MS Homo sapiens
50 TUBA1B 10376
Affinity Capture-MS Homo sapiens
51 PCCA 5095
Affinity Capture-MS Homo sapiens
52 ITLN2  
Affinity Capture-MS Homo sapiens
53 SCAMP2 10066
Affinity Capture-MS Homo sapiens
54 KRT9 3857
Affinity Capture-MS Homo sapiens
55 LRRC8E 80131
Affinity Capture-MS Homo sapiens
56 KRT2 3849
Affinity Capture-MS Homo sapiens
57 RAB11FIP5 26056
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
58 DDX39B 7919
Affinity Capture-MS Homo sapiens
59 GJB5  
Affinity Capture-MS Homo sapiens
60 RAD21 5885
Affinity Capture-Western Homo sapiens
61 PRSS58  
Affinity Capture-MS Homo sapiens
62 RPL11 6135
Affinity Capture-MS Homo sapiens
63 PLEKHG6  
Affinity Capture-MS Homo sapiens
64 RING1 6015
Affinity Capture-MS Homo sapiens
65 NUMA1 4926
Affinity Capture-MS Homo sapiens
66 TUBB 203068
Affinity Capture-MS Homo sapiens
67 FANCD2  
Affinity Capture-MS Homo sapiens
68 NBEA  
Affinity Capture-MS Homo sapiens
69 TMEM176B 28959
Affinity Capture-MS Homo sapiens
70 MAGEB4  
Affinity Capture-MS Homo sapiens
71 UCP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 COG2 22796
Affinity Capture-MS Homo sapiens
73 ARMC6 93436
Affinity Capture-MS Homo sapiens
74 FRMD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 TMEM237 65062
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 ZNF491  
Affinity Capture-MS Homo sapiens
77 SLC3A2 6520
Affinity Capture-MS Homo sapiens
78 FN3KRP 79672
Affinity Capture-MS Homo sapiens
79 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
80 RIBC1  
Affinity Capture-MS Homo sapiens
81 HBM  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 RHOBTB1  
Affinity Capture-MS Homo sapiens
83 EEF1A2 1917
Affinity Capture-MS Homo sapiens
84 TWF1 5756
Affinity Capture-MS Homo sapiens
85 Dynll1 56455
Affinity Capture-MS Mus musculus
86 SMAD6  
Affinity Capture-MS Homo sapiens
87 NPB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 MAPK15  
Affinity Capture-MS Homo sapiens
89 CLCN2  
Affinity Capture-MS Homo sapiens
90 PIGR 5284
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 COMMD1 150684
Affinity Capture-MS Homo sapiens
92 HVCN1 84329
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 FAM122C  
Affinity Capture-MS Homo sapiens
94 SGK1  
Affinity Capture-MS Homo sapiens
95 MYRFL  
Affinity Capture-MS Homo sapiens
96 ZNF695  
Affinity Capture-MS Homo sapiens
97 SSFA2 6744
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 DDX3X 1654
Affinity Capture-MS Homo sapiens
99 USB1  
Affinity Capture-MS Homo sapiens
100 TIMM10  
Affinity Capture-MS Homo sapiens
101 NHLRC2 374354
Affinity Capture-MS Homo sapiens
102 CDK6 1021
Affinity Capture-MS Homo sapiens
103 GTF2B 2959
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 RAB11FIP1 80223
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
105 FKBP14  
Affinity Capture-MS Homo sapiens
106 HBQ1  
Affinity Capture-MS Homo sapiens
107 TMEM257  
Affinity Capture-MS Homo sapiens
108 KLK10 5655
Affinity Capture-MS Homo sapiens
109 FLNA 2316
Affinity Capture-MS Homo sapiens
110 PRDX1 5052
Affinity Capture-MS Homo sapiens
111 FOXN3 1112
Affinity Capture-MS Homo sapiens
112 KRT10 3858
Affinity Capture-MS Homo sapiens
113 STK11 6794
Affinity Capture-MS Homo sapiens
114 PRKX 5613
Affinity Capture-MS Homo sapiens
115 ATP11C 286410
Affinity Capture-MS Homo sapiens
116 CUL4A 8451
Affinity Capture-MS Homo sapiens
117 KIAA0922  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PIGR is involved
PathwayEvidenceSource
Immune System TAS Reactome
Innate Immune System TAS Reactome
Neutrophil degranulation TAS Reactome





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