Experiment description of studies that identified TMEM176B in exosomes

1 Experiment ID 1203 MISEV standards ✔ EM Biophysical techniques ✔ SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 34887515     Organism Homo sapiens Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ." Journal name Nat Cell Biol Publication year 2021 Sample Colorectal cancer cells Sample name DiFi Isolation/purification methods Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation OptiPrep density gradient centrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Mass spectrometry RNA sequencing

Protein-protein interactions for TMEM176B

Protein Interactor ExoCarta ID Identification method PubMed Species 1 JCHAIN 3512 Affinity Capture-MS Homo sapiens 2 IGLC2 3538 Affinity Capture-MS Homo sapiens 3 BPIFA1 51297 Affinity Capture-MS Homo sapiens 4 LYZ 4069 Affinity Capture-MS Homo sapiens 5 RBM45   Affinity Capture-MS Homo sapiens 6 IGHA1 3493 Affinity Capture-MS Homo sapiens 7 IGLL5 100423062 Affinity Capture-MS Homo sapiens 8 IGHM 3507 Affinity Capture-MS Homo sapiens 9 IGHA2 3494 Affinity Capture-MS Homo sapiens 10 AZGP1 563 Affinity Capture-MS Homo sapiens 11 HP 3240 Affinity Capture-MS Homo sapiens 12 CST4 1472 Affinity Capture-MS Homo sapiens 13 LACRT 90070 Affinity Capture-MS Homo sapiens 14 BPIFB1 92747 Affinity Capture-MS Homo sapiens 15 SCGB2A1 4246 Affinity Capture-MS Homo sapiens 16 PRR4 11272 Affinity Capture-MS Homo sapiens 17 LCN1 3933 Affinity Capture-MS Homo sapiens 18 LCN2 3934 Affinity Capture-MS Homo sapiens 19 LTF 4057 Affinity Capture-MS Homo sapiens 20 SERPINA3 12 Affinity Capture-MS Homo sapiens 21 PIGR 5284 Affinity Capture-MS Homo sapiens 22 DMBT1 1755 Affinity Capture-MS Homo sapiens View the network

Pathways in which TMEM176B is involved

No pathways found