Gene description for ARMC6
Gene name armadillo repeat containing 6
Gene symbol ARMC6
Other names/aliases R30923_1
Species Homo sapiens
 Database cross references - ARMC6
ExoCarta ExoCarta_93436
Vesiclepedia VP_93436
Entrez Gene 93436
HGNC 25049
UniProt Q6NXE6  
 ARMC6 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Thymus 23844026    
 Gene ontology annotations for ARMC6
Biological Process
    hematopoietic progenitor cell differentiation GO:0002244 IBA
Subcellular Localization
    cytosol GO:0005829 IDA
 Experiment description of studies that identified ARMC6 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
6
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ARMC6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 C1orf198 84886
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 Cul1 26965
Affinity Capture-MS Mus musculus
3 FOXA3  
Affinity Capture-MS Homo sapiens
4 CCT3 7203
Affinity Capture-MS Homo sapiens
5 TMEM161A  
Affinity Capture-MS Homo sapiens
6 GALNT1 2589
Affinity Capture-MS Homo sapiens
7 CMTM8  
Affinity Capture-MS Homo sapiens
8 SSB 6741
Affinity Capture-MS Homo sapiens
9 LPHN1  
Affinity Capture-MS Homo sapiens
10 UBA1 7317
Co-fractionation Homo sapiens
11 TUBB8 347688
Affinity Capture-MS Homo sapiens
12 F2R 2149
Affinity Capture-MS Homo sapiens
13 SPTLC1 10558
Affinity Capture-MS Homo sapiens
14 SPNS1 83985
Affinity Capture-MS Homo sapiens
15 C4BPA 722
Affinity Capture-MS Homo sapiens
16 PYCR1 5831
Affinity Capture-MS Homo sapiens
17 SLC27A6  
Affinity Capture-MS Homo sapiens
18 STK36  
Affinity Capture-MS Homo sapiens
19 TMEM126A 84233
Affinity Capture-MS Homo sapiens
20 MFSD3  
Affinity Capture-MS Homo sapiens
21 GCN1L1 10985
Affinity Capture-MS Homo sapiens
22 PNKD  
Affinity Capture-MS Homo sapiens
23 SLC16A10 117247
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 SLC38A5 92745
Affinity Capture-MS Homo sapiens
25 MGST1 4257
Affinity Capture-MS Homo sapiens
26 MCU 90550
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 B3GNT2 10678
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 C1orf159 54991
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 FAM57A  
Affinity Capture-MS Homo sapiens
30 SLC27A2 11001
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 RMDN2 151393
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 MAGED2 10916
Affinity Capture-MS Homo sapiens
33 USMG5 84833
Affinity Capture-MS Homo sapiens
34 F2RL1  
Affinity Capture-MS Homo sapiens
35 SLC7A11 23657
Affinity Capture-MS Homo sapiens
36 CCT5 22948
Affinity Capture-MS Homo sapiens
37 GPR17 2840
Affinity Capture-MS Homo sapiens
38 KIF14 9928
Affinity Capture-MS Homo sapiens
39 TMEM246 84302
Affinity Capture-MS Homo sapiens
40 CCT2 10576
Affinity Capture-MS Homo sapiens
41 DDX19B 11269
Affinity Capture-MS Homo sapiens
42 PPM1B 5495
Affinity Capture-MS Homo sapiens
43 TCP1 6950
Affinity Capture-MS Homo sapiens
44 CNNM4 26504
Affinity Capture-MS Homo sapiens
45 PLBD1 79887
Affinity Capture-MS Homo sapiens
46 ADPGK 83440
Affinity Capture-MS Homo sapiens
47 CTDP1 9150
Affinity Capture-MS Homo sapiens
48 GGT7 2686
Affinity Capture-MS Homo sapiens
49 CLU 1191
Affinity Capture-MS Homo sapiens
50 P2RY8  
Affinity Capture-MS Homo sapiens
51 SLC2A8 29988
Affinity Capture-MS Homo sapiens
52 CPS1 1373
Affinity Capture-MS Homo sapiens
53 MICU2 221154
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 SSTR5 6755
Affinity Capture-MS Homo sapiens
55 TUBA1B 10376
Affinity Capture-MS Homo sapiens
56 OGT 8473
Reconstituted Complex Homo sapiens
57 NPTN 27020
Affinity Capture-MS Homo sapiens
58 ENPP1 5167
Affinity Capture-MS Homo sapiens
59 XPOT 11260
Affinity Capture-MS Homo sapiens
60 PIGR 5284
Affinity Capture-MS Homo sapiens
61 LCN1 3933
Affinity Capture-MS Homo sapiens
62 PCSK9 255738
Affinity Capture-MS Homo sapiens
63 SDF4 51150
Affinity Capture-MS Homo sapiens
64 ICAM5 7087
Affinity Capture-MS Homo sapiens
65 SEC61B 10952
Affinity Capture-MS Homo sapiens
66 PSG11  
Affinity Capture-MS Homo sapiens
67 TRIP13 9319
Affinity Capture-MS Homo sapiens
68 TUBB 203068
Affinity Capture-MS Homo sapiens
69 ARL6IP4  
Affinity Capture-MS Homo sapiens
70 CLN3 1201
Affinity Capture-MS Homo sapiens
71 AIFM1 9131
Affinity Capture-MS Homo sapiens
72 XPO1 7514
Affinity Capture-MS Homo sapiens
73 IGHA1 3493
Affinity Capture-MS Homo sapiens
74 HIGD1A 25994
Affinity Capture-MS Homo sapiens
75 SLC20A2 6575
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 CCT6A 908
Affinity Capture-MS Homo sapiens
77 SLC27A4 10999
Affinity Capture-MS Homo sapiens
78 SLC35E1 79939
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 CUL3 8452
Affinity Capture-MS Homo sapiens
80 ARCN1 372
Affinity Capture-MS Homo sapiens
81 WRAP73 49856
Affinity Capture-MS Homo sapiens
82 FUS 2521
Affinity Capture-MS Homo sapiens
83 AQP3  
Affinity Capture-MS Homo sapiens
84 RCN1 5954
Affinity Capture-MS Homo sapiens
85 SLC38A10 124565
Affinity Capture-MS Homo sapiens
86 ATP5J2 9551
Affinity Capture-MS Homo sapiens
87 MICB  
Affinity Capture-MS Homo sapiens
88 ALDH3A2 224
Affinity Capture-MS Homo sapiens
89 GALNT11 63917
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 DNAI2  
Affinity Capture-MS Homo sapiens
91 CCT4 10575
Affinity Capture-MS Homo sapiens
92 GPR45  
Affinity Capture-MS Homo sapiens
93 EGFR 1956
Affinity Capture-MS Homo sapiens
94 CCT8 10694
Affinity Capture-MS Homo sapiens
95 DAAM1 23002
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 B3GAT3 26229
Affinity Capture-MS Homo sapiens
97 METTL9 51108
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 STX10 8677
Affinity Capture-MS Homo sapiens
99 ARL8B 55207
Affinity Capture-MS Homo sapiens
100 PFDN5 5204
Co-fractionation Homo sapiens
101 AP1S1 1174
Affinity Capture-MS Homo sapiens
102 METTL21B  
Affinity Capture-MS Homo sapiens
103 ATP6V1H 51606
Affinity Capture-MS Homo sapiens
104 TRIP6 7205
Affinity Capture-MS Homo sapiens
105 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
106 FBXW11  
Affinity Capture-MS Homo sapiens
107 MUL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 TERF2  
Affinity Capture-MS Homo sapiens
109 ABCB6 10058
Affinity Capture-MS Homo sapiens
110 MFSD4  
Affinity Capture-MS Homo sapiens
111 SLCO4A1 28231
Affinity Capture-MS Homo sapiens
112 EPHA4 2043
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 ACAA2 10449
Affinity Capture-MS Homo sapiens
114 EPHX4 253152
Affinity Capture-MS Homo sapiens
115 SLC25A15  
Affinity Capture-MS Homo sapiens
116 HSPB1 3315
Affinity Capture-MS Homo sapiens
117 CCT7 10574
Affinity Capture-MS Homo sapiens
118 CD80 941
Affinity Capture-MS Homo sapiens
119 LPCAT2 54947
Affinity Capture-MS Homo sapiens
120 PLD3 23646
Affinity Capture-MS Homo sapiens
121 BRD1 23774
Affinity Capture-MS Homo sapiens
122 ZNF146  
Affinity Capture-MS Homo sapiens
123 SLC20A1 6574
Affinity Capture-MS Homo sapiens
124 C9orf72  
Affinity Capture-MS Homo sapiens
125 RPA3 6119
Proximity Label-MS Homo sapiens
126 EP300 2033
Affinity Capture-MS Homo sapiens
127 SCO2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ARMC6 is involved
No pathways found





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