Gene description for GGT7
Gene name gamma-glutamyltransferase 7
Gene symbol GGT7
Other names/aliases D20S101
GGT4
GGTL3
GGTL5
dJ18C9.2
Species Homo sapiens
 Database cross references - GGT7
ExoCarta ExoCarta_2686
Vesiclepedia VP_2686
Entrez Gene 2686
HGNC 4259
MIM 612342
UniProt Q9UJ14  
 GGT7 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for GGT7
Molecular Function
    protein binding GO:0005515 IPI
    glutathione hydrolase activity GO:0036374 IBA
    leukotriene C4 gamma-glutamyl transferase activity GO:0103068 IEA
Biological Process
    glutathione biosynthetic process GO:0006750 IEA
    glutathione catabolic process GO:0006751 IBA
    leukotriene D4 biosynthetic process GO:1901750 ISS
    negative regulation of response to oxidative stress GO:1902883 IMP
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified GGT7 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for GGT7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RAMP3  
Affinity Capture-MS Homo sapiens
2 GJD3  
Proximity Label-MS Homo sapiens
3 METTL7A 25840
Proximity Label-MS Homo sapiens
4 KLK5 25818
Affinity Capture-MS Homo sapiens
5 MANEAL 149175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 ALG12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 TUSC3 7991
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 HSD17B11 51170
Proximity Label-MS Homo sapiens
9 B3GALT4  
Affinity Capture-MS Homo sapiens
10 ST6GALNAC3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 FFAR1  
Affinity Capture-MS Homo sapiens
12 NAALAD2 10003
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 RIPK3 11035
Affinity Capture-MS Homo sapiens
14 PPTC7 160760
Affinity Capture-MS Homo sapiens
15 HYAL1 3373
Affinity Capture-MS Homo sapiens
16 NDRG2 57447
Affinity Capture-MS Homo sapiens
17 GCAT  
Affinity Capture-MS Homo sapiens
18 TSPO2  
Two-hybrid Homo sapiens
19 ABHD14A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 SEC11C 90701
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 FAHD2B  
Affinity Capture-MS Homo sapiens
22 POMT1 10585
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 COMMD4 54939
Affinity Capture-MS Homo sapiens
24 DHDH  
Affinity Capture-MS Homo sapiens
25 ZDHHC9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 ACADS 35
Affinity Capture-MS Homo sapiens
27 MTNR1B  
Two-hybrid Homo sapiens
28 PNPLA5  
Affinity Capture-MS Homo sapiens
29 NUBP2 10101
Affinity Capture-MS Homo sapiens
30 GPR25  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
31 EMD 2010
Proximity Label-MS Homo sapiens
32 GGT7 2686
Co-purification Homo sapiens
Co-purification Homo sapiens
33 FAM96B 51647
Affinity Capture-MS Homo sapiens
34 PIGM  
Affinity Capture-MS Homo sapiens
35 PIGB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 WNT5A 7474
Affinity Capture-MS Homo sapiens
37 ARL17A  
Affinity Capture-MS Homo sapiens
38 RPN1 6184
Proximity Label-MS Homo sapiens
39 CLDN19  
Two-hybrid Homo sapiens
40 LHFPL5  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
41 SEC61B 10952
Proximity Label-MS Homo sapiens
42 UPK2 7379
Affinity Capture-MS Homo sapiens
43 BCAP31 10134
Proximity Label-MS Homo sapiens
44 RPN2 6185
Proximity Label-MS Homo sapiens
45 LRRC59 55379
Proximity Label-MS Homo sapiens
46 LMNB1 4001
Proximity Label-MS Homo sapiens
47 TM4SF18  
Affinity Capture-MS Homo sapiens
48 RNF130  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 MGARP  
Affinity Capture-MS Homo sapiens
50 HSD3B7 80270
Proximity Label-MS Homo sapiens
51 CTAG1B  
Affinity Capture-MS Homo sapiens
52 TMEM242  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
53 CMTM7  
Two-hybrid Homo sapiens
54 ARMC6 93436
Affinity Capture-MS Homo sapiens
55 LNPEP 4012
Two-hybrid Homo sapiens
56 C1orf210  
Affinity Capture-MS Homo sapiens
57 CNR2  
Affinity Capture-MS Homo sapiens
58 SLC35A4  
Two-hybrid Homo sapiens
59 NAAA  
Affinity Capture-MS Homo sapiens
60 MPZL1 9019
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 OBSCN 84033
Affinity Capture-MS Homo sapiens
62 HOXB1  
Affinity Capture-MS Homo sapiens
63 CST9L  
Affinity Capture-MS Homo sapiens
64 ALG9 79796
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 MALL  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
66 LYZL2  
Affinity Capture-MS Homo sapiens
67 MANEA 79694
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 SPCS3 60559
Affinity Capture-MS Homo sapiens
69 STK16 8576
Affinity Capture-MS Homo sapiens
70 HLA-G 3135
Affinity Capture-MS Homo sapiens
71 LSR 51599
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 COMMD5 28991
Affinity Capture-MS Homo sapiens
73 ASIC4  
Affinity Capture-MS Homo sapiens
74 DCP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 ASPDH  
Affinity Capture-MS Homo sapiens
76 APOM 55937
Affinity Capture-MS Homo sapiens
77 GZMH  
Affinity Capture-MS Homo sapiens
78 ST3GAL4 6484
Affinity Capture-MS Homo sapiens
79 DDX11 1663
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 SEC62 7095
Proximity Label-MS Homo sapiens
81 FAM69A 388650
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 HTR4  
Two-hybrid Homo sapiens
83 ENTPD6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 TCTEX1D4  
Affinity Capture-MS Homo sapiens
85 HYI 81888
Affinity Capture-MS Homo sapiens
86 CLEC2D  
Affinity Capture-MS Homo sapiens
87 CKAP4 10970
Proximity Label-MS Homo sapiens
88 PLD6  
Affinity Capture-MS Homo sapiens
89 CHSY3 337876
Affinity Capture-MS Homo sapiens
90 CLEC4E  
Affinity Capture-MS Homo sapiens
91 ATP2A1 487
Proximity Label-MS Homo sapiens
View the network image/svg+xml



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