Gene ontology annotations for APOM
Experiment description of studies that identified APOM in exosomes
1
Experiment ID
497
MISEV standards
✘
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
T/C-28a2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
2
Experiment ID
498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
T/C-28a2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
3
Experiment ID
488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Homo sapiens
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Mesenchymal stem cells
Sample name
UCMSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
4
Experiment ID
275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25844599
Organism
Homo sapiens
Experiment description
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors
"Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name
Oncotarget
Publication year
2015
Sample
Prostate cancer cells
Sample name
DU145 - Docetaxel sensitive
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.12-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry/Flow cytometry/Western blotting
5
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
6
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for APOM
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
SEC11C
90701
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
2
DCBLD2
131566
Affinity Capture-MS
Homo sapiens
3
HFE
Affinity Capture-MS
Homo sapiens
4
MR1
Affinity Capture-MS
Homo sapiens
5
GPX8
493869
Affinity Capture-MS
Homo sapiens
6
ESYT2
57488
Affinity Capture-MS
Homo sapiens
7
SLC7A11
23657
Affinity Capture-MS
Homo sapiens
8
CLGN
1047
Affinity Capture-MS
Homo sapiens
9
CNTNAP3
Affinity Capture-MS
Homo sapiens
10
SCNN1A
Affinity Capture-MS
Homo sapiens
11
CACNA2D2
9254
Affinity Capture-MS
Homo sapiens
12
ENTPD6
Affinity Capture-MS
Homo sapiens
13
TCTN3
Affinity Capture-MS
Homo sapiens
14
PPM1B
5495
Affinity Capture-MS
Homo sapiens
15
CLPTM1
1209
Affinity Capture-MS
Homo sapiens
16
TUBB8
347688
Affinity Capture-MS
Homo sapiens
17
HSPA13
6782
Affinity Capture-MS
Homo sapiens
18
USP16
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
19
ADPGK
83440
Affinity Capture-MS
Homo sapiens
20
ITGA6
3655
Affinity Capture-MS
Homo sapiens
21
GGT7
2686
Affinity Capture-MS
Homo sapiens
22
HGH1
51236
Two-hybrid
Homo sapiens
23
CYB5D2
Affinity Capture-MS
Homo sapiens
24
TMEM67
91147
Affinity Capture-MS
Homo sapiens
25
HS6ST1
Affinity Capture-MS
Homo sapiens
26
CNNM3
26505
Affinity Capture-MS
Homo sapiens
27
CDYL
9425
Affinity Capture-MS
Homo sapiens
28
ADAM21
Affinity Capture-MS
Homo sapiens
29
ITGA7
3679
Affinity Capture-MS
Homo sapiens
30
B3GNT2
10678
Affinity Capture-MS
Homo sapiens
31
CNTNAP3B
Affinity Capture-MS
Homo sapiens
32
CLSTN3
9746
Affinity Capture-MS
Homo sapiens
33
ASIC1
Affinity Capture-MS
Homo sapiens
34
CT45A2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
35
KLF6
Two-hybrid
Homo sapiens
36
ADGRG6
57211
Affinity Capture-MS
Homo sapiens
37
HLA-DQB1
3119
Affinity Capture-MS
Homo sapiens
38
PLXNA3
55558
Affinity Capture-MS
Homo sapiens
39
BDH1
622
Affinity Capture-MS
Homo sapiens
40
SEMA4C
54910
Affinity Capture-MS
Homo sapiens
41
KIAA0922
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which APOM is involved