Gene description for ADPGK
Gene name ADP-dependent glucokinase
Gene symbol ADPGK
Other names/aliases 2610017G09Rik
ADP-GK
Species Homo sapiens
 Database cross references - ADPGK
ExoCarta ExoCarta_83440
Vesiclepedia VP_83440
Entrez Gene 83440
HGNC 25250
MIM 611861
UniProt Q9BRR6  
 ADPGK identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for ADPGK
Molecular Function
    ADP-specific glucokinase activity GO:0043843 EXP
    ADP-specific glucokinase activity GO:0043843 IBA
    ADP-specific glucokinase activity GO:0043843 IDA
    metal ion binding GO:0046872 IEA
Biological Process
    glucose metabolic process GO:0006006 IBA
    glucose metabolic process GO:0006006 IDA
    glycolytic process through glucose-6-phosphate GO:0061620 TAS
Subcellular Localization
    extracellular region GO:0005576 IEA
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum membrane GO:0005789 TAS
    membrane GO:0016020 HDA
 Experiment description of studies that identified ADPGK in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ADPGK
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UPK2 7379
Affinity Capture-MS Homo sapiens
2 SLC39A12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 C1GALT1C1 29071
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
5 CSGALNACT2 55454
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 KLK15  
Affinity Capture-MS Homo sapiens
7 UBQLN4 56893
Two-hybrid Homo sapiens
8 TMEM30A 55754
Affinity Capture-MS Homo sapiens
9 REEP5 7905
Affinity Capture-MS Homo sapiens
10 ABCB8 11194
Co-fractionation Homo sapiens
11 STX12 23673
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 KIF14 9928
Affinity Capture-MS Homo sapiens
13 LRRC59 55379
Proximity Label-MS Homo sapiens
14 TMEM214 54867
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 MFSD4  
Affinity Capture-MS Homo sapiens
16 HPN  
Affinity Capture-MS Homo sapiens
17 RPA2 6118
Proximity Label-MS Homo sapiens
18 HMOX2 3163
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 FAM213A 84293
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 DPEP2  
Affinity Capture-MS Homo sapiens
21 MIPEP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 EXTL2 2135
Affinity Capture-MS Homo sapiens
23 TOR1B 27348
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 EMC1 23065
Affinity Capture-MS Homo sapiens
25 COL18A1 80781
Affinity Capture-MS Homo sapiens
26 PARK2  
Affinity Capture-MS Homo sapiens
27 DLK1  
Affinity Capture-MS Homo sapiens
28 TIMP3 7078
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 TOR1AIP1 26092
Affinity Capture-MS Homo sapiens
30 ARMC6 93436
Affinity Capture-MS Homo sapiens
31 APOM 55937
Affinity Capture-MS Homo sapiens
32 KIAA1467 57613
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 APEX1 328
Affinity Capture-RNA Homo sapiens
34 GALNT7 51809
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 ST3GAL4 6484
Affinity Capture-MS Homo sapiens
36 PLTP 5360
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 TPST2 8459
Affinity Capture-MS Homo sapiens
38 GALNT4 8693
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 RPA3 6119
Proximity Label-MS Homo sapiens
40 C16orf58 64755
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 B4GALT7 11285
Affinity Capture-MS Homo sapiens
42 OGT 8473
Reconstituted Complex Homo sapiens
43 PXDN 7837
Affinity Capture-MS Homo sapiens
44 PAM 5066
Affinity Capture-MS Homo sapiens
45 PDIA5 10954
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 HLA-C 3107
Affinity Capture-MS Homo sapiens
47 GPR182  
Affinity Capture-MS Homo sapiens
48 PTPRN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 GXYLT1 283464
Affinity Capture-MS Homo sapiens
50 NUP35 129401
Proximity Label-MS Homo sapiens
51 CLEC2B  
Affinity Capture-MS Homo sapiens
52 STX7 8417
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 HK1 3098
Co-fractionation Homo sapiens
54 P2RX2  
Affinity Capture-MS Homo sapiens
55 HTR1B  
Affinity Capture-MS Homo sapiens
56 ST14 6768
Affinity Capture-MS Homo sapiens
57 CKAP4 10970
Affinity Capture-MS Homo sapiens
58 CCPG1 9236
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 MGAT1 4245
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 LMNA 4000
Proximity Label-MS Homo sapiens
61 HLA-DPA1  
Affinity Capture-MS Homo sapiens
62 DPAGT1 1798
Affinity Capture-MS Homo sapiens
63 CCDC47 57003
Affinity Capture-MS Homo sapiens
64 SEC61B 10952
Proximity Label-MS Homo sapiens
65 TMPRSS13  
Affinity Capture-MS Homo sapiens
66 UGT8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 EPHB4 2050
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 RNF139  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ADPGK is involved
PathwayEvidenceSource
Glucose metabolism TAS Reactome
Glycolysis TAS Reactome
Metabolism TAS Reactome
Metabolism of carbohydrates TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here