Gene description for FAM213A
Gene name family with sequence similarity 213, member A
Gene symbol FAM213A
Other names/aliases C10orf58
PAMM
Species Homo sapiens
 Database cross references - FAM213A
ExoCarta ExoCarta_84293
Vesiclepedia VP_84293
Entrez Gene 84293
HGNC 28651
UniProt Q9BRX8  
 FAM213A identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Thymus 23844026    
 Gene ontology annotations for FAM213A
Molecular Function
    antioxidant activity GO:0016209 IBA
    antioxidant activity GO:0016209 IDA
Biological Process
    regulation of osteoclast differentiation GO:0045670 IDA
    cellular oxidant detoxification GO:0098869 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified FAM213A in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FAM213A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GRPR  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 SLC39A12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 CANX 821
Affinity Capture-MS Homo sapiens
4 CES1P1  
Affinity Capture-MS Homo sapiens
5 FAM131B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 CSGALNACT2 55454
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 TMEM106A  
Affinity Capture-MS Homo sapiens
8 TACR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 TMEM30A 55754
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 IVL 3713
Affinity Capture-MS Homo sapiens
11 CCL3  
Affinity Capture-MS Homo sapiens
12 RPN2 6185
Proximity Label-MS Homo sapiens
13 GPR17 2840
Affinity Capture-MS Homo sapiens
14 HLA-G 3135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 PINK1  
Affinity Capture-MS Homo sapiens
16 ADH7  
Affinity Capture-MS Homo sapiens
17 HPN  
Affinity Capture-MS Homo sapiens
18 MME 4311
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 CRYAB 1410
Affinity Capture-MS Homo sapiens
20 SCEL 8796
Affinity Capture-MS Homo sapiens
21 ANXA1 301
Affinity Capture-MS Homo sapiens
22 SPG21 51324
Affinity Capture-MS Homo sapiens
23 PDGFRA 5156
Affinity Capture-MS Homo sapiens
24 TSPAN15 23555
Affinity Capture-MS Homo sapiens
25 IL1RN 3557
Affinity Capture-MS Homo sapiens
26 TLR5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 ADPGK 83440
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 NIPAL1  
Affinity Capture-MS Homo sapiens
29 SERPINB1 1992
Affinity Capture-MS Homo sapiens
30 KLRD1  
Affinity Capture-MS Homo sapiens
31 GPR114  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 COPE 11316
Affinity Capture-MS Homo sapiens
33 COPA 1314
Affinity Capture-MS Homo sapiens
34 APP 351
Reconstituted Complex Homo sapiens
35 EVPL 2125
Affinity Capture-MS Homo sapiens
36 A2ML1 144568
Affinity Capture-MS Homo sapiens
37 UGT1A5  
Affinity Capture-MS Homo sapiens
38 AKR1C2  
Affinity Capture-MS Homo sapiens
39 SRRT 51593
Affinity Capture-MS Homo sapiens
40 CLEC12B  
Affinity Capture-MS Homo sapiens
41 ST3GAL4 6484
Affinity Capture-MS Homo sapiens
42 PPL 5493
Affinity Capture-MS Homo sapiens
43 CHRNB2  
Affinity Capture-MS Homo sapiens
44 HLA-DQA1 3117
Affinity Capture-MS Homo sapiens
45 SLC5A4  
Affinity Capture-MS Homo sapiens
46 SLC3A2 6520
Affinity Capture-MS Homo sapiens
47 GDPD5 81544
Affinity Capture-MS Homo sapiens
48 COQ9  
Affinity Capture-MS Homo sapiens
49 SCGB2A2  
Affinity Capture-MS Homo sapiens
50 A4GNT  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 CENPM  
Affinity Capture-MS Homo sapiens
52 HSPA1A 3303
Affinity Capture-MS Homo sapiens
53 SSUH2  
Affinity Capture-MS Homo sapiens
54 DSG3 1830
Affinity Capture-MS Homo sapiens
55 ALDH3A1 218
Affinity Capture-MS Homo sapiens
56 SLC18A1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 YIPF3 25844
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 S100A16 140576
Affinity Capture-MS Homo sapiens
59 TRIM29 23650
Affinity Capture-MS Homo sapiens
60 HLA-C 3107
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 GLT6D1  
Affinity Capture-MS Homo sapiens
62 TSPAN5 10098
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 SPRR3 6707
Affinity Capture-MS Homo sapiens
64 RTN1 6252
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 AKAP1 8165
Proximity Label-MS Homo sapiens
66 CES1  
Affinity Capture-MS Homo sapiens
67 ENDOU  
Affinity Capture-MS Homo sapiens
68 NXPE2  
Affinity Capture-MS Homo sapiens
69 CHRND  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 CRNN 49860
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FAM213A is involved
No pathways found





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