Gene description for CSGALNACT2
Gene name chondroitin sulfate N-acetylgalactosaminyltransferase 2
Gene symbol CSGALNACT2
Other names/aliases CHGN2
GALNACT-2
GALNACT2
PRO0082
Species Homo sapiens
 Database cross references - CSGALNACT2
ExoCarta ExoCarta_55454
Vesiclepedia VP_55454
Entrez Gene 55454
HGNC 24292
UniProt Q8N6G5  
 CSGALNACT2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for CSGALNACT2
Molecular Function
    protein binding GO:0005515 IPI
    acetylgalactosaminyltransferase activity GO:0008376 IDA
    metal ion binding GO:0046872 IEA
    glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity GO:0047237 IEA
    glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity GO:0047238 IBA
    glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity GO:0047238 TAS
Biological Process
    proteoglycan biosynthetic process GO:0030166 IDA
    chondroitin sulfate biosynthetic process GO:0030206 IBA
    chondroitin sulfate biosynthetic process GO:0030206 TAS
    chondroitin sulfate proteoglycan biosynthetic process GO:0050650 IDA
    dermatan sulfate proteoglycan biosynthetic process GO:0050651 IDA
    dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0050652 TAS
    chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0050653 TAS
Subcellular Localization
    Golgi membrane GO:0000139 NAS
    Golgi membrane GO:0000139 TAS
    membrane GO:0016020 HDA
    Golgi cisterna membrane GO:0032580 IEA
 Experiment description of studies that identified CSGALNACT2 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for CSGALNACT2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HSD17B11 51170
Two-hybrid Homo sapiens
2 CX3CL1  
Affinity Capture-MS Homo sapiens
3 CHRNA4  
Affinity Capture-MS Homo sapiens
4 TMEM143  
Two-hybrid Homo sapiens
5 P2RX4 5025
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 KIAA2013 90231
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 MANEAL 149175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 SYNE4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
9 GOSR2 9570
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 TNFSF18 8995
Affinity Capture-MS Homo sapiens
11 MYEOV2 150678
Affinity Capture-MS Homo sapiens
12 MGAT4C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 NDUFB9 4715
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 SULF2 55959
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 GINM1 116254
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 MUC1 4582
Two-hybrid Homo sapiens
17 GPRC5B 51704
Affinity Capture-MS Homo sapiens
18 RHOA 387
Affinity Capture-MS Homo sapiens
19 C3orf52  
Affinity Capture-MS Homo sapiens
20 SUN2 25777
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 HIATL1 84641
Two-hybrid Homo sapiens
22 SLC30A5 64924
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 TMTC4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 LMBRD1 55788
Affinity Capture-MS Homo sapiens
25 TMEM59 9528
Affinity Capture-MS Homo sapiens
26 SSMEM1  
Two-hybrid Homo sapiens
27 CLASP2 23122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 TRIM59  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 GOLIM4 27333
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 SLC30A1 7779
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 CD70 970
Affinity Capture-MS Homo sapiens
32 ATP1B4  
Two-hybrid Homo sapiens
33 LRRC57 255252
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 FUT8 2530
Affinity Capture-MS Homo sapiens
35 ADPGK 83440
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 MCOLN1 57192
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 UGT8  
Affinity Capture-MS Homo sapiens
38 UBE2I 7329
Two-hybrid Homo sapiens
39 TCTN2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 CREB3L1  
Two-hybrid Homo sapiens
41 CCDC8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 SLC35E3  
Two-hybrid Homo sapiens
43 TMX4 56255
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 PIGS 94005
Affinity Capture-MS Homo sapiens
45 STX5 6811
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 ARL13B 200894
Two-hybrid Homo sapiens
47 B3GALNT1 8706
Affinity Capture-MS Homo sapiens
48 RMDN3 55177
Affinity Capture-MS Homo sapiens
49 PNLDC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 UTP15 84135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 TMEM52B 120939
Two-hybrid Homo sapiens
52 CLEC4F  
Affinity Capture-MS Homo sapiens
53 GPAA1 8733
Affinity Capture-MS Homo sapiens
54 EMC3 55831
Affinity Capture-MS Homo sapiens
55 EMC8 10328
Affinity Capture-MS Homo sapiens
56 IQCB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 B3GNT3 10331
Affinity Capture-MS Homo sapiens
58 SLC30A6 55676
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 SLC35A5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 LPAR1 1902
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 GPR152  
Two-hybrid Homo sapiens
62 NADSYN1 55191
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 FAM134C 162427
Two-hybrid Homo sapiens
64 NDUFB3 4709
Affinity Capture-MS Homo sapiens
65 IPPK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 TSPAN1 10103
Affinity Capture-MS Homo sapiens
67 EMC2 9694
Affinity Capture-MS Homo sapiens
68 IMPAD1 54928
Affinity Capture-MS Homo sapiens
69 B3GAT3 26229
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 MPPE1 65258
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 POGLUT1 56983
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 FAM213A 84293
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 NDUFC2 4718
Affinity Capture-MS Homo sapiens
74 B3GALT5  
Affinity Capture-MS Homo sapiens
75 FUT1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 CLDN2 9075
Two-hybrid Homo sapiens
77 DPP6  
Affinity Capture-MS Homo sapiens
78 MANEA 79694
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 SUN1 23353
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 PLB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 TMEM214 54867
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 GOSR1 9527
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 ASIC5  
Affinity Capture-MS Homo sapiens
84 EMC4 51234
Affinity Capture-MS Homo sapiens
85 FKRP 79147
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 CHST5  
Affinity Capture-MS Homo sapiens
87 EXTL2 2135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 FCGR2A 2212
Two-hybrid Homo sapiens
89 CREB1  
Affinity Capture-MS Homo sapiens
90 ATF1  
Affinity Capture-MS Homo sapiens
91 CLEC12B  
Affinity Capture-MS Homo sapiens
92 ST3GAL4 6484
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 BSND  
Two-hybrid Homo sapiens
94 TPST1 8460
Affinity Capture-MS Homo sapiens
95 TPST2 8459
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 SLC8A3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 PRAF2 11230
Affinity Capture-MS Homo sapiens
98 CHSY1 22856
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 CSGALNACT1 55790
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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