Gene description for UTP15
Gene name UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
Gene symbol UTP15
Other names/aliases NET21
Species Homo sapiens
 Database cross references - UTP15
ExoCarta ExoCarta_84135
Vesiclepedia VP_84135
Entrez Gene 84135
HGNC 25758
MIM 616194
UniProt Q8TED0  
 UTP15 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for UTP15
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
Biological Process
    rRNA processing GO:0006364 IBA
    ribosomal small subunit biogenesis GO:0042274 IDA
    positive regulation of transcription by RNA polymerase I GO:0045943 IBA
    positive regulation of transcription by RNA polymerase I GO:0045943 IMP
    positive regulation of rRNA processing GO:2000234 IMP
Subcellular Localization
    fibrillar center GO:0001650 IDA
    nucleoplasm GO:0005654 TAS
    nucleolus GO:0005730 IBA
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IDA
    endoplasmic reticulum GO:0005783 IDA
    small-subunit processome GO:0032040 IDA
 Experiment description of studies that identified UTP15 in exosomes
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for UTP15
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TECTB  
Affinity Capture-MS Homo sapiens
2 MNDA 4332
Affinity Capture-MS Homo sapiens
3 ANLN 54443
Affinity Capture-MS Homo sapiens
4 KLHL20  
Affinity Capture-MS Homo sapiens
5 PGK2 5232
Affinity Capture-MS Homo sapiens
6 Sumo3  
Affinity Capture-MS Mus musculus
7 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
8 CSGALNACT2 55454
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 ZBTB2 57621
Affinity Capture-MS Homo sapiens
10 HNRNPCL2 440563
Affinity Capture-MS Homo sapiens
11 NOP58 51602
Co-fractionation Homo sapiens
12 KIF14 9928
Affinity Capture-MS Homo sapiens
13 FTL 2512
Affinity Capture-MS Homo sapiens
14 SORT1 6272
Affinity Capture-MS Homo sapiens
15 RBM19 9904
Co-fractionation Homo sapiens
16 DNAJB6 10049
Proximity Label-MS Homo sapiens
17 LAMP3  
Affinity Capture-MS Homo sapiens
18 XPO1 7514
Affinity Capture-MS Homo sapiens
19 EIF3K 27335
Co-fractionation Homo sapiens
20 ZNF324B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 RIT1 6016
Negative Genetic Homo sapiens
22 SIRT7  
Affinity Capture-MS Homo sapiens
23 HDAC6 10013
Affinity Capture-MS Homo sapiens
24 NLGN3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 SRP9 6726
Affinity Capture-MS Homo sapiens
26 TNFRSF1A 7132
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 CUL3 8452
Affinity Capture-MS Homo sapiens
28 CHCHD1  
Proximity Label-MS Homo sapiens
29 DCAF13 25879
Affinity Capture-MS Homo sapiens
30 MPHOSPH6 10200
Affinity Capture-MS Homo sapiens
31 ATM 472
Affinity Capture-MS Homo sapiens
32 ECT2 1894
Affinity Capture-MS Homo sapiens
33 KRR1 11103
Co-fractionation Homo sapiens
34 TBL3 10607
Co-fractionation Homo sapiens
35 KLHL34  
Affinity Capture-MS Homo sapiens
36 Ncaph  
Affinity Capture-MS Mus musculus
37 KCNE3  
Affinity Capture-MS Homo sapiens
38 RBM4B  
Affinity Capture-MS Homo sapiens
39 SUZ12  
Affinity Capture-MS Homo sapiens
40 BRIX1 55299
Co-fractionation Homo sapiens
41 WDR36 134430
Co-fractionation Homo sapiens
42 NOL11  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
43 SMURF1 57154
Affinity Capture-MS Homo sapiens
44 USP36  
Affinity Capture-MS Homo sapiens
45 NOP2 4839
Affinity Capture-MS Homo sapiens
46 SKAP1 8631
Affinity Capture-MS Homo sapiens
47 RBM4 5936
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 PARK2  
Affinity Capture-MS Homo sapiens
49 UBR5 51366
Co-fractionation Homo sapiens
50 CIRH1A 84916
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 CHMP4B 128866
Affinity Capture-MS Homo sapiens
52 EXOSC2 23404
Affinity Capture-MS Homo sapiens
53 CDH5  
Affinity Capture-MS Homo sapiens
54 NOL7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 HECTD1 25831
Affinity Capture-MS Homo sapiens
56 KIF23 9493
Affinity Capture-MS Homo sapiens
57 DNAJC9 23234
Proximity Label-MS Homo sapiens
58 EGFR 1956
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
59 ANAPC10  
Co-fractionation Homo sapiens
60 NFKBIL1  
Affinity Capture-MS Homo sapiens
61 RPS8 6202
Co-fractionation Homo sapiens
62 EXOSC5 56915
Affinity Capture-MS Homo sapiens
63 WDR75  
Affinity Capture-MS Homo sapiens
64 MPHOSPH10 10199
Co-fractionation Homo sapiens
65 GRSF1 2926
Proximity Label-MS Homo sapiens
66 C1D  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 WDR43 23160
Affinity Capture-MS Homo sapiens
68 RPA4  
Proximity Label-MS Homo sapiens
69 DDRGK1 65992
Affinity Capture-MS Homo sapiens
70 RNF2  
Affinity Capture-MS Homo sapiens
71 RRP9 9136
Affinity Capture-MS Homo sapiens
72 FBL 2091
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 CDH23 64072
Affinity Capture-MS Homo sapiens
74 HEATR1 55127
Co-fractionation Homo sapiens
75 PRC1 9055
Affinity Capture-MS Homo sapiens
76 RTN1 6252
Affinity Capture-MS Homo sapiens
77 KRAS 3845
Negative Genetic Homo sapiens
78 TBC1D15 64786
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 NPM1 4869
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
80 SOX2  
Affinity Capture-MS Homo sapiens
81 PIPSL 266971
Affinity Capture-MS Homo sapiens
82 DGCR2 9993
Affinity Capture-MS Homo sapiens
83 RPA3 6119
Proximity Label-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here