Gene description for RTN1
Gene name reticulon 1
Gene symbol RTN1
Other names/aliases NSP
Species Homo sapiens
 Database cross references - RTN1
ExoCarta ExoCarta_6252
Vesiclepedia VP_6252
Entrez Gene 6252
HGNC 10467
MIM 600865
UniProt Q16799  
 RTN1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for RTN1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    neuron differentiation GO:0030182 IEP
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IDA
    endomembrane system GO:0012505 IBA
    integral component of endoplasmic reticulum membrane GO:0030176 TAS
 Experiment description of studies that identified RTN1 in exosomes
1
Experiment ID 488
MISEV standards
EM
EV Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
CANX
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for RTN1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 BCL2L1 598
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
2 FAM160A2 84067
Two-hybrid Homo sapiens
3 UGCG 7357
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
4 PLEKHF2 79666
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which RTN1 is involved
No pathways found





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