Gene description for RTN3
Gene name reticulon 3
Gene symbol RTN3
Other names/aliases ASYIP
HAP
NSPL2
NSPLII
RTN3-A1
Species Homo sapiens
 Database cross references - RTN3
ExoCarta ExoCarta_10313
Vesiclepedia VP_10313
Entrez Gene 10313
HGNC 10469
MIM 604249
UniProt O95197  
 RTN3 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Thymus 23844026    
 Gene ontology annotations for RTN3
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    apoptotic process GO:0006915 IEA
    brain development GO:0007420 IBA
    vesicle-mediated transport GO:0016192 IEA
    neuron differentiation GO:0030182 IBA
    endoplasmic reticulum tubular network organization GO:0071786 IMP
    endoplasmic reticulum tubular network formation GO:0071787 IBA
    endoplasmic reticulum tubular network formation GO:0071787 IDA
    negative regulation of amyloid-beta formation GO:1902430 IDA
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    extracellular space GO:0005615 TAS
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 IDA
    Golgi apparatus GO:0005794 IDA
    plasma membrane GO:0005886 TAS
    postsynaptic density GO:0014069 IBA
    neuron projection GO:0043005 IBA
 Experiment description of studies that identified RTN3 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
12
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
16
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RTN3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 COPG2 26958
Affinity Capture-MS Homo sapiens
3 ZNF391  
Two-hybrid Homo sapiens
4 GJD3  
Proximity Label-MS Homo sapiens
5 DERL2 51009
Affinity Capture-MS Homo sapiens
6 MITD1 129531
Two-hybrid Homo sapiens
7 VAPA 9218
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
8 METTL7A 25840
Proximity Label-MS Homo sapiens
9 ARL6IP5 10550
Affinity Capture-MS Homo sapiens
10 RPA2 6118
Proximity Label-MS Homo sapiens
11 GLP1R  
PCA Homo sapiens
12 PTPN9 5780
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
13 COPB2 9276
Affinity Capture-MS Homo sapiens
14 HSD17B11 51170
Proximity Label-MS Homo sapiens
15 PTPN1 5770
Proximity Label-MS Homo sapiens
16 ARL6IP1 23204
Affinity Capture-MS Homo sapiens
17 STX4 6810
Proximity Label-MS Homo sapiens
18 RTN4 57142
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
19 PTRH2 51651
Affinity Capture-MS Homo sapiens
20 TBL2 26608
Affinity Capture-MS Homo sapiens
21 SLC30A8  
Two-hybrid Homo sapiens
22 CCR2  
Two-hybrid Homo sapiens
23 COPE 11316
Affinity Capture-MS Homo sapiens
24 RAB3B 5865
Proximity Label-MS Homo sapiens
25 COL4A3BP 10087
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
26 MMP15 4324
Affinity Capture-MS Homo sapiens
27 TM9SF1 10548
Affinity Capture-MS Homo sapiens
28 SIGMAR1 10280
Affinity Capture-MS Homo sapiens
29 YWHAG 7532
Affinity Capture-MS Homo sapiens
30 SSR1 6745
Proximity Label-MS Homo sapiens
31 C10orf35  
Affinity Capture-MS Homo sapiens
32 AGTR1  
Two-hybrid Homo sapiens
33 COPZ1 22818
Affinity Capture-MS Homo sapiens
34 VAPB 9217
Affinity Capture-MS Homo sapiens
35 SLC25A46 91137
Proximity Label-MS Homo sapiens
36 LETMD1  
Affinity Capture-MS Homo sapiens
37 RAB35 11021
Proximity Label-MS Homo sapiens
38 ESYT2 57488
Affinity Capture-MS Homo sapiens
39 FGFR1 2260
Two-hybrid Homo sapiens
40 SACM1L 22908
Two-hybrid Homo sapiens
41 YWHAB 7529
Affinity Capture-MS Homo sapiens
42 NUP155 9631
Proximity Label-MS Homo sapiens
43 KIAA1715 80856
Proximity Label-MS Homo sapiens
44 PFN1 5216
Proximity Label-MS Homo sapiens
45 LRRC59 55379
Proximity Label-MS Homo sapiens
46 TOLLIP 54472
Proximity Label-MS Homo sapiens
47 EMD 2010
Proximity Label-MS Homo sapiens
48 REEP4  
Affinity Capture-MS Homo sapiens
49 IFITM3 10410
Affinity Capture-MS Homo sapiens
50 PLA2G4A 5321
Co-fractionation Homo sapiens
51 RTN1 6252
Affinity Capture-MS Homo sapiens
52 AMFR 267
Affinity Capture-MS Homo sapiens
53 GPR35  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
54 KDSR 2531
Affinity Capture-MS Homo sapiens
55 SCAMP2 10066
Affinity Capture-MS Homo sapiens
56 RPN1 6184
Proximity Label-MS Homo sapiens
57 TMEM70  
Affinity Capture-MS Homo sapiens
58 SEC61B 10952
Proximity Label-MS Homo sapiens
59 CDIPT 10423
Two-hybrid Homo sapiens
60 TEX2 55852
Affinity Capture-MS Homo sapiens
61 REEP5 7905
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 SNX1 6642
Two-hybrid Homo sapiens
63 PLN  
Two-hybrid Homo sapiens
64 C4orf32  
Affinity Capture-MS Homo sapiens
65 RPN2 6185
Proximity Label-MS Homo sapiens
66 PLEKHF2 79666
Two-hybrid Homo sapiens
67 ATL3 25923
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 XPO1 7514
Affinity Capture-MS Homo sapiens
69 PANX1 24145
Proximity Label-MS Homo sapiens
70 MSMO1 6307
Affinity Capture-MS Homo sapiens
71 DOCK7 85440
Affinity Capture-MS Homo sapiens
72 DHCR24 1718
Affinity Capture-MS Homo sapiens
73 HMOX2 3163
Affinity Capture-MS Homo sapiens
74 GOLT1B 51026
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 BCAP31 10134
Proximity Label-MS Homo sapiens
76 HSD3B7 80270
Proximity Label-MS Homo sapiens
77 RTN2 6253
Affinity Capture-MS Homo sapiens
78 STIM1 6786
Proximity Label-MS Homo sapiens
79 ATP1B3 483
Co-fractionation Homo sapiens
80 TMEM246 84302
Affinity Capture-MS Homo sapiens
81 YIPF5 81555
Affinity Capture-MS Homo sapiens
82 GPR152  
Two-hybrid Homo sapiens
83 FAM134C 162427
Affinity Capture-MS Homo sapiens
84 RABAC1 10567
Affinity Capture-MS Homo sapiens
85 RPA3 6119
Proximity Label-MS Homo sapiens
86 FXR2 9513
Two-hybrid Homo sapiens
87 ATP2A1 487
Proximity Label-MS Homo sapiens
88 RAB9A 9367
Proximity Label-MS Homo sapiens
89 HSPA1A 3303
Cross-Linking-MS (XL-MS) Homo sapiens
90 SLC30A3  
Two-hybrid Homo sapiens
91 RMDN2 151393
Two-hybrid Homo sapiens
92 COPA 1314
Affinity Capture-MS Homo sapiens
93 ANKRD28 23243
Co-fractionation Homo sapiens
94 CCR8  
Two-hybrid Homo sapiens
95 REEP6  
Affinity Capture-MS Homo sapiens
96 DRD2  
Two-hybrid Homo sapiens
97 RAB33A 9363
Two-hybrid Homo sapiens
98 FAM160A2 84067
Two-hybrid Homo sapiens
99 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
100 SPOP  
Two-hybrid Homo sapiens
101 TMEM208  
Affinity Capture-MS Homo sapiens
102 UBA6 55236
Cross-Linking-MS (XL-MS) Homo sapiens
103 TP53 7157
Affinity Capture-MS Homo sapiens
104 PGRMC1 10857
Affinity Capture-MS Homo sapiens
105 RTN3 10313
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
106 TMEM68  
Affinity Capture-MS Homo sapiens
107 EMC7 56851
Affinity Capture-MS Homo sapiens
108 SNX19  
Affinity Capture-MS Homo sapiens
109 PRTFDC1 56952
Co-fractionation Homo sapiens
110 TSPAN15 23555
Affinity Capture-MS Homo sapiens
111 DCTN2 10540
Proximity Label-MS Homo sapiens
112 UGCG 7357
Two-hybrid Homo sapiens
113 STK26 51765
Affinity Capture-MS Homo sapiens
114 DDX58 23586
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
115 TRIM25 7706
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
116 TERF1 7013
Two-hybrid Homo sapiens
117 PPP2R3C  
Two-hybrid Homo sapiens
118 BCL2  
Affinity Capture-Western Homo sapiens
119 SEC62 7095
Proximity Label-MS Homo sapiens
120 RAB7A 7879
Proximity Label-MS Homo sapiens
121 RAB11A 8766
Proximity Label-MS Homo sapiens
122 SMPD2 6610
Affinity Capture-MS Homo sapiens
123 DNAJC1 64215
Proximity Label-MS Homo sapiens
124 CKAP4 10970
Proximity Label-MS Homo sapiens
125 SCAMP3 10067
Affinity Capture-MS Homo sapiens
126 NAGPA 51172
Affinity Capture-MS Homo sapiens
127 ESYT1 23344
Affinity Capture-MS Homo sapiens
128 DERL1 79139
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which RTN3 is involved
PathwayEvidenceSource
Neuronal System TAS Reactome
Protein-protein interactions at synapses TAS Reactome
Synaptic adhesion-like molecules TAS Reactome





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