Experiment description of studies that identified TMEM246 in exosomes

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for TMEM246

Protein Interactor ExoCarta ID Identification method PubMed Species 1 SLC39A12   Affinity Capture-MS Homo sapiens 2 P2RX4 5025 Affinity Capture-MS Homo sapiens 3 P2RY2 5029 Affinity Capture-MS Homo sapiens 4 VIPR2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 ADORA2B   Affinity Capture-MS Homo sapiens 6 HLA-B 3106 Affinity Capture-MS Homo sapiens 7 TMEM59 9528 Affinity Capture-MS Homo sapiens 8 TTYH1   Affinity Capture-MS Homo sapiens 9 GP9 2815 Affinity Capture-MS Homo sapiens 10 SLC39A4 55630 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 HCST   Affinity Capture-MS Homo sapiens 12 PEX19 5824 Affinity Capture-MS Homo sapiens 13 FA2H   Affinity Capture-MS Homo sapiens 14 ACKR2   Affinity Capture-MS Homo sapiens 15 KCNK1   Affinity Capture-MS Homo sapiens 16 RTN3 10313 Affinity Capture-MS Homo sapiens 17 ERGIC3 51614 Affinity Capture-MS Homo sapiens 18 BSCL2   Affinity Capture-MS Homo sapiens 19 TSPAN15 23555 Affinity Capture-MS Homo sapiens 20 GOLPH3 64083 Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens 21 TYROBP   Affinity Capture-MS Homo sapiens 22 NIPAL1   Affinity Capture-MS Homo sapiens 23 AQP3   Affinity Capture-MS Homo sapiens 24 OPRL1 4987 Affinity Capture-MS Homo sapiens 25 LPAR1 1902 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 KIR2DS2   Affinity Capture-MS Homo sapiens 27 ARMC6 93436 Affinity Capture-MS Homo sapiens 28 GOLPH3L 55204 Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens 29 PIGN 23556 Affinity Capture-MS Homo sapiens 30 HLA-DQA1 3117 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 31 TMED10 10972 Affinity Capture-MS Homo sapiens 32 B3GNT2 10678 Two-hybrid Homo sapiens 33 HLA-DPA1   Affinity Capture-MS Homo sapiens 34 SPPL2B 56928 Affinity Capture-MS Homo sapiens 35 UGT1A7 54577 Affinity Capture-MS Homo sapiens 36 CMTM5   Affinity Capture-MS Homo sapiens 37 POMK   Affinity Capture-MS Homo sapiens 38 SLC39A5 283375 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 PTAFR   Affinity Capture-MS Homo sapiens 40 TSPAN8 7103 Affinity Capture-MS Homo sapiens 41 GPR55   Affinity Capture-MS Homo sapiens 42 SLC1A1 6505 Affinity Capture-MS Homo sapiens 43 Clspn   Affinity Capture-MS Mus musculus 44 PTPRO 5800 Affinity Capture-MS Homo sapiens 45 KIAA1644   Affinity Capture-MS Homo sapiens 46 TSPAN3 10099 Affinity Capture-MS Homo sapiens 47 HLA-C 3107 Affinity Capture-MS Homo sapiens View the network

Pathways in which TMEM246 is involved

No pathways found