Gene description for GOLPH3L
Gene name golgi phosphoprotein 3-like
Gene symbol GOLPH3L
Other names/aliases GPP34R
Species Homo sapiens
 Database cross references - GOLPH3L
ExoCarta ExoCarta_55204
Vesiclepedia VP_55204
Entrez Gene 55204
HGNC 24882
MIM 612208
UniProt Q9H4A5  
 GOLPH3L identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for GOLPH3L
Molecular Function
    protein binding GO:0005515 IPI
    phosphatidylinositol-4-phosphate binding GO:0070273 IBA
    phosphatidylinositol-4-phosphate binding GO:0070273 IDA
    cargo adaptor activity GO:0140312 IDA
Biological Process
    retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum GO:0006890 IBA
    Golgi organization GO:0007030 IBA
    Golgi organization GO:0007030 IMP
    Golgi to plasma membrane protein transport GO:0043001 IBA
    Golgi vesicle budding GO:0048194 IBA
    positive regulation of protein secretion GO:0050714 IMP
    protein targeting to Golgi apparatus GO:0140450 IMP
Subcellular Localization
    Golgi membrane GO:0000139 IC
    Golgi apparatus GO:0005794 IDA
    trans-Golgi network GO:0005802 IBA
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    Golgi cisterna GO:0031985 IBA
    Golgi cisterna membrane GO:0032580 IEA
    trans-Golgi network membrane GO:0032588 IC
 Experiment description of studies that identified GOLPH3L in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for GOLPH3L
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 COPB1 1315
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
2 EMC6 83460
Affinity Capture-MS Homo sapiens
3 TMEM246 84302
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
4 COPG2 26958
Affinity Capture-MS Homo sapiens
5 MANEA 79694
Affinity Capture-MS Homo sapiens
6 C5AR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 C5AR1  
Affinity Capture-MS Homo sapiens
8 GPRC5C 55890
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 VNN2  
Affinity Capture-MS Homo sapiens
10 IRF9 10379
Affinity Capture-MS Homo sapiens
11 C1GALT1 56913
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
12 EBAG9 9166
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
13 GOLPH3 64083
Cross-Linking-MS (XL-MS) Homo sapiens
14 CHST6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 C3orf58 205428
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
16 MAPK1 5594
Co-fractionation Homo sapiens
17 GOLIM4 27333
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
18 P2RX1 5023
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 GALNT6 11226
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
20 ZDHHC17 23390
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
21 GALR3  
Affinity Capture-MS Homo sapiens
22 MAN1B1 11253
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
23 TNFRSF10D 8793
Affinity Capture-MS Homo sapiens
24 POMGNT1 55624
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
25 CANT1 124583
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
26 TNFRSF8 943
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 GCNT1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
28 ARCN1 372
Affinity Capture-MS Homo sapiens
29 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
30 MGAT2 4247
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
31 COPE 11316
Affinity Capture-MS Homo sapiens
32 GDF5OS  
Affinity Capture-MS Homo sapiens
33 GLB1L2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 SHMT2 6472
Affinity Capture-RNA Homo sapiens
35 CASC4 113201
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
36 COPA 1314
Affinity Capture-MS Homo sapiens
37 ENTPD7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 COPG1 22820
Affinity Capture-MS Homo sapiens
39 PNKD  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 FAM20B 9917
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
41 HTT 3064
Two-hybrid Homo sapiens
42 KRTCAP3 200634
Affinity Capture-MS Homo sapiens
43 EXT1 2131
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
44 COPB2 9276
Affinity Capture-MS Homo sapiens
45 MOV10 4343
Affinity Capture-RNA Homo sapiens
46 RWDD2B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 FAM69A 388650
Affinity Capture-MS Homo sapiens
48 VCP 7415
Affinity Capture-MS Homo sapiens
49 S1PR1 1901
Affinity Capture-MS Homo sapiens
50 GLT8D1 55830
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
51 SLC39A5 283375
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 ARL6IP1 23204
Two-hybrid Homo sapiens
53 IMPAD1 54928
Affinity Capture-MS Homo sapiens
54 GALNT7 51809
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
55 TPST2 8459
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
56 SERBP1 26135
Affinity Capture-MS Homo sapiens
57 TPST1 8460
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
58 GALNT2 2590
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
59 B4GALT4 8702
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
60 LNX1  
Two-hybrid Homo sapiens
61 COPZ1 22818
Affinity Capture-MS Homo sapiens
62 CD80 941
Affinity Capture-MS Homo sapiens
63 FAM3C 10447
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
64 GLG1 2734
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which GOLPH3L is involved
No pathways found





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