Gene description for P2RX1
Gene name	purinergic receptor P2X, ligand gated ion channel, 1
Gene symbol	P2RX1
Other names/aliases	P2X1
Species	Homo sapiens
Database cross references - P2RX1
ExoCarta	ExoCarta_5023
Vesiclepedia	VP_5023
Entrez Gene	5023
HGNC	8533
MIM	600845
UniProt	P51575
P2RX1 identified in exosomes derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for P2RX1

Molecular Function     purinergic nucleotide receptor activity GO:0001614 IDA     extracellular ATP-gated cation channel activity GO:0004931 IEA     zinc ion binding GO:0008270 IEA     drug binding GO:0008144 IEA     calcium channel activity GO:0005262 TAS     ATP binding GO:0005524 IEA     cation channel activity GO:0005261 IDA Biological Process     serotonin secretion by platelet GO:0002554 IEA     transport GO:0006810 TAS     protein heterooligomerization GO:0051291 IEA     signal transduction GO:0007165 TAS     platelet activation GO:0030168 IEA     synaptic transmission, glutamatergic GO:0035249 IEA     insemination GO:0007320 IEA     ion transport GO:0006811 IDA     positive regulation of ion transport GO:0043270 IEA     ceramide biosynthetic process GO:0046513 IEA     purinergic nucleotide receptor signaling pathway GO:0035590 IEA     neuronal action potential GO:0019228 IEA     regulation of vascular smooth muscle contraction GO:0003056 IEA     protein homooligomerization GO:0051260 IEA     calcium ion transmembrane transport GO:0070588 TAS     regulation of calcium ion transport GO:0051924 IEA     activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 IEA     vasoconstriction GO:0042310 IEA     regulation of blood pressure GO:0008217 IEA     blood coagulation GO:0007596 TAS     response to ATP GO:0033198 IEA Subcellular Localization     plasma membrane GO:0005886 TAS     external side of cell outer membrane GO:0031240 IEA     postsynaptic membrane GO:0045211 IEA     integral component of nuclear inner membrane GO:0005639 IBA     integral component of plasma membrane GO:0005887 IEA     membrane raft GO:0045121 IEA     protein complex GO:0043234 IEA     neuron projection GO:0043005 IEA