Gene description for P2RX1
Gene name	purinergic receptor P2X, ligand gated ion channel, 1
Gene symbol	P2RX1
Other names/aliases	P2X1
Species	Homo sapiens
Database cross references - P2RX1
ExoCarta	ExoCarta_5023
Vesiclepedia	VP_5023
Entrez Gene	5023
HGNC	8533
MIM	600845
UniProt	P51575
P2RX1 identified in sEVs derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for P2RX1

Molecular Function     purinergic nucleotide receptor activity GO:0001614 IDA     extracellularly ATP-gated monoatomic cation channel activity GO:0004931 IBA     extracellularly ATP-gated monoatomic cation channel activity GO:0004931 IDA     monoatomic cation channel activity GO:0005261 IDA     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     identical protein binding GO:0042802 IEA     suramin binding GO:0043924 IEA     protein-containing complex binding GO:0044877 IEA     ligand-gated calcium channel activity GO:0099604 IDA Biological Process     serotonin secretion by platelet GO:0002554 IEA     regulation of vascular associated smooth muscle contraction GO:0003056 IEA     monoatomic ion transport GO:0006811 IDA     apoptotic process GO:0006915 IEA     signal transduction GO:0007165 TAS     insemination GO:0007320 IEA     regulation of blood pressure GO:0008217 IEA     neuronal action potential GO:0019228 IEA     calcium-mediated signaling GO:0019722 IEA     platelet activation GO:0030168 IEA     response to ATP GO:0033198 IEA     synaptic transmission, glutamatergic GO:0035249 IEA     purinergic nucleotide receptor signaling pathway GO:0035590 IEA     ceramide biosynthetic process GO:0046513 IEA     excitatory postsynaptic potential GO:0060079 IEA     calcium ion transmembrane transport GO:0070588 IBA     regulation of presynaptic cytosolic calcium ion concentration GO:0099509 IEA     positive regulation of calcium ion import across plasma membrane GO:1905665 IEA     regulation of synaptic vesicle exocytosis GO:2000300 IEA Subcellular Localization     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     external side of plasma membrane GO:0009897 IEA     secretory granule membrane GO:0030667 TAS     protein-containing complex GO:0032991 IEA     specific granule membrane GO:0035579 TAS     membrane raft GO:0045121 IDA     postsynaptic membrane GO:0045211 IEA     presynaptic active zone membrane GO:0048787 IEA     glutamatergic synapse GO:0098978 IEA