Gene description for FAM20B
Gene name family with sequence similarity 20, member B
Gene symbol FAM20B
Other names/aliases gxk1
Species Homo sapiens
 Database cross references - FAM20B
ExoCarta ExoCarta_9917
Vesiclepedia VP_9917
Entrez Gene 9917
HGNC 23017
MIM 611063
UniProt O75063  
 FAM20B identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for FAM20B
Molecular Function
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    kinase activity GO:0016301 IEA
    phosphotransferase activity, alcohol group as acceptor GO:0016773 IBA
    phosphotransferase activity, alcohol group as acceptor GO:0016773 IDA
    metal ion binding GO:0046872 IEA
Biological Process
    proteoglycan biosynthetic process GO:0030166 IBA
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    nucleoplasm GO:0005654 IDA
    Golgi apparatus GO:0005794 IDA
 Experiment description of studies that identified FAM20B in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for FAM20B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 NUPL2 11097
Affinity Capture-MS Homo sapiens
2 P2RX4 5025
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 BSCL2  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
4 ATP2A3 489
Affinity Capture-MS Homo sapiens
5 TOR1A 1861
Affinity Capture-MS Homo sapiens
6 UBL4A 8266
Affinity Capture-MS Homo sapiens
7 CHRNA4  
Affinity Capture-MS Homo sapiens
8 TMEM80  
Two-hybrid Homo sapiens
9 FFAR2  
Two-hybrid Homo sapiens
10 GOLPH3 64083
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
11 CD79B 974
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 PEX19 5824
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 P2RX1 5023
Affinity Capture-MS Homo sapiens
14 Tbck  
Affinity Capture-MS Mus musculus
15 SLC39A7 7922
Affinity Capture-MS Homo sapiens
16 LPAR2 9170
Affinity Capture-MS Homo sapiens
17 GPR152  
Two-hybrid Homo sapiens
18 CENPH  
Affinity Capture-MS Homo sapiens
19 SYNE4  
Affinity Capture-MS Homo sapiens
20 KRTAP15-1  
Affinity Capture-MS Homo sapiens
21 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
22 PARK2  
Affinity Capture-MS Homo sapiens
23 PHAX  
Affinity Capture-MS Homo sapiens
24 B3GAT2  
Affinity Capture-MS Homo sapiens
25 P2RY8  
Affinity Capture-MS Homo sapiens
26 FFAR1  
Affinity Capture-MS Homo sapiens
27 LPAR1 1902
Affinity Capture-MS Homo sapiens
28 METTL9 51108
Affinity Capture-MS Homo sapiens
29 KCNJ6  
Two-hybrid Homo sapiens
30 CD27  
Affinity Capture-MS Homo sapiens
31 FAM209A 200232
Two-hybrid Homo sapiens
32 SAAL1 113174
Affinity Capture-MS Homo sapiens
33 GOLPH3L 55204
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
34 PBXIP1 57326
Affinity Capture-MS Homo sapiens
35 GALNT6 11226
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 SPPL2B 56928
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 TMEM130  
Affinity Capture-MS Homo sapiens
38 HTR1B  
Affinity Capture-MS Homo sapiens
39 TIMMDC1  
Two-hybrid Homo sapiens
40 FAM174A 345757
Affinity Capture-MS Homo sapiens
41 IPPK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 CLEC2B  
Affinity Capture-MS Homo sapiens
43 PVR 5817
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 ENTPD2 954
Affinity Capture-MS Homo sapiens
45 KLRC1  
Affinity Capture-MS Homo sapiens
46 TRAV20  
Affinity Capture-MS Homo sapiens
47 SCN3B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 AVPR2  
Affinity Capture-MS Homo sapiens
49 ASPHD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 CHRNA3 1136
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 DKKL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which FAM20B is involved
No pathways found





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