Gene description for CD80
Gene name	CD80 molecule
Gene symbol	CD80
Other names/aliases	B7 B7-1 B7.1 BB1 CD28LG CD28LG1 LAB7
Species	Homo sapiens
Database cross references - CD80
ExoCarta	ExoCarta_941
Vesiclepedia	VP_941
Entrez Gene	941
HGNC	1700
MIM	112203
UniProt	P33681
CD80 identified in exosomes derived from the following tissue/cell type
B cells	17641064
Dendritic cells	14582906

Gene ontology annotations for CD80

Molecular Function     virus receptor activity GO:0001618 IEA     protein binding GO:0005515 IPI     coreceptor activity GO:0015026 NAS     receptor ligand activity GO:0048018 IDA Biological Process     negative regulation of T cell mediated immunity GO:0002710 IDA     immune response GO:0006955 IBA     cell surface receptor signaling pathway GO:0007166 IBA     positive regulation of signal transduction GO:0009967 NAS     T cell costimulation GO:0031295 IBA     positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032725 NAS     positive regulation of interleukin-2 production GO:0032743 NAS     intracellular signal transduction GO:0035556 NAS     positive regulation of T cell proliferation GO:0042102 IBA     T cell activation GO:0042110 IDA     negative regulation of T cell proliferation GO:0042130 IBA     positive regulation of T-helper 1 cell differentiation GO:0045627 NAS     positive regulation of DNA-templated transcription GO:0045893 NAS     symbiont entry into host cell GO:0046718 IEA     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IDA     cellular response to lipopolysaccharide GO:0071222 IBA Subcellular Localization     plasma membrane GO:0005886 IC     plasma membrane GO:0005886 TAS     external side of plasma membrane GO:0009897 IBA     cell surface GO:0009986 HDA     protein complex involved in cell adhesion GO:0098636 IDA