Gene description for CD80
Gene name	CD80 molecule
Gene symbol	CD80
Other names/aliases	B7 B7-1 B7.1 BB1 CD28LG CD28LG1 LAB7
Species	Homo sapiens
Database cross references - CD80
ExoCarta	ExoCarta_941
Entrez Gene	941
HGNC	1700
MIM	112203
UniProt	P33681
CD80 identified in exosomes derived from the following tissue/cell type
B cells	17641064
Dendritic cells	14582906

Gene ontology annotations for CD80

Molecular Function     coreceptor activity GO:0015026 NAS     protein binding GO:0005515 IPI Biological Process     positive regulation of T-helper 1 cell differentiation GO:0045627 NAS     intracellular signal transduction GO:0035556 NAS     positive regulation of signal transduction GO:0009967 NAS     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IDA     positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process GO:0045425 NAS     positive regulation of transcription, DNA-templated GO:0045893 NAS     T cell activation GO:0042110 IC     innate immune response GO:0045087 TAS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     positive regulation of interleukin-2 biosynthetic process GO:0045086 NAS     epidermal growth factor receptor signaling pathway GO:0007173 TAS     cell-cell signaling GO:0007267 IC     positive regulation of alpha-beta T cell proliferation GO:0046641 IEA     Fc-epsilon receptor signaling pathway GO:0038095 TAS     T cell costimulation GO:0031295 TAS     viral process GO:0016032 IEA     phosphatidylinositol-mediated signaling GO:0048015 TAS     fibroblast growth factor receptor signaling pathway GO:0008543 TAS Subcellular Localization     intracellular GO:0005622 TAS     cell surface GO:0009986 IDA     external side of plasma membrane GO:0009897 IEA     integral component of membrane GO:0016021 IC     plasma membrane GO:0005886 TAS